LOC100911093 (CCA tRNA nucleotidyltransferase 1, mitochondrial-like) - Rat Genome Database

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Gene: LOC100911093 (CCA tRNA nucleotidyltransferase 1, mitochondrial-like) Rattus norvegicus
Analyze
No known orthologs.
Symbol: LOC100911093
Name: CCA tRNA nucleotidyltransferase 1, mitochondrial-like
RGD ID: 6494996
Description: Predicted to enable RNA binding activity; nucleotide binding activity; and nucleotidyltransferase activity. Predicted to be involved in tRNA 3'-terminal CCA addition.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: AABR07005533.1
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81180,154,702 - 180,157,040 (-)NCBIGRCr8
mRatBN7.21170,720,730 - 170,722,745 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1170,721,272 - 170,722,576 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01185,171,373 - 185,173,658 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1185,171,547 - 185,172,851 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01192,143,145 - 192,145,139 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1168,540,686 - 168,542,962 (-)NCBICelera
Cytogenetic Map1q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
mitochondrion  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in LOC100911093
3 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1100357752183970443Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1102813953201278233Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1102813953201278233Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat
1300158Bp173Blood pressure QTL 1733.48arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1115540693185145286Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
631199Cm23Cardiac mass QTL 234.60.0004heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1115585465172949803Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118944897199050459Rat
631544Bp84Blood pressure QTL 845.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350408181759564Rat
1358189Cstrr1Cold stress response QTL 10.0001catecholamine amount (VT:0010543)urine norepinephrine level (CMO:0001629)1123350408182418476Rat
1641895Bp298Blood pressure QTL 298arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1123350408182418476Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1123350408182418476Rat
631549Bp89Blood pressure QTL 895.7arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350581201284552Rat
9685802Bp376Blood pressure QTL 376arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1126540680171540680Rat
738006Anxrr14Anxiety related response QTL 1440.00035locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1130636910175636910Rat
738028Anxrr12Anxiety related response QTL 124.90.00001locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1130636910175636910Rat
6893347Bw98Body weight QTL 980.20.53body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
6893361Bw104Body weight QTL 1040.590.27body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
1558645Bw55Body weight QTL 553.20.004body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
71118Thym1Thymus enlargement QTL 110.170.001thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1136829932181829932Rat
724550Thym3Thymus enlargement QTL 37.820.001thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1136829932181829932Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1136830018181830018Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1143506580212458660Rat
61348Bp30Blood pressure QTL 302.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1144017057197814409Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1144267353196383668Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1144267353222987745Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
634315Niddm45Non-insulin dependent diabetes mellitus QTL 457.16blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1144267916172949660Rat
61379Bp44Blood pressure QTL 4419.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1144267916174133260Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1149448574221264292Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1151162512201278233Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512201278233Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1151162512201278233Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1151162512201278233Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1151162766225824951Rat
61343Bp28Blood pressure QTL 28arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1151646613196646613Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
2303622Vencon6Ventilatory control QTL 60.001respiration trait (VT:0001943)respiration rate (CMO:0000289)1154561505199561505Rat
1582204Livw1Liver weight QTL 13.60.0003liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)1155422851172949803Rat
4889428Stresp24Stress response QTL 240.05heart pumping trait (VT:2000009)absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)1155866514200866514Rat
631548Bp88Blood pressure QTL 8850.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1156677124176484451Rat
1354618Kidm15Kidney mass QTL 155kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)1156677124201278233Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1156677124218753816Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
61347Bp197Blood pressure QTL 1974.2arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1158633083203633083Rat
2292222Bp307Blood pressure QTL 3073.060.0014arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393213533942Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393243914901Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164747424209747424Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1164747424209747424Rat
737974Bp161Blood pressure QTL 1610.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1164747558181133855Rat
2312558Glom17Glomerulus QTL 173.90.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1166532971191278129Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1167909849212909849Rat
619614Bp78Blood pressure QTL 780.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1169112897197261052Rat
619614Bp78Blood pressure QTL 780.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1169112897197261052Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1169537671214537671Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1169537671214537671Rat

Markers in Region
RH132465  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21170,720,499 - 170,720,686 (-)MAPPERmRatBN7.2
mRatBN7.24139,703,366 - 139,703,552 (+)MAPPERmRatBN7.2
Rnor_6.04138,868,974 - 138,869,159NCBIRnor6.0
Rnor_5.04203,339,362 - 203,339,547UniSTSRnor5.0
RGSC_v3.44142,138,148 - 142,138,333UniSTSRGSC3.4
RGSC_v3.41174,575,261 - 174,575,446UniSTSRGSC3.4
Celera4128,415,713 - 128,415,898UniSTS
Celera1168,540,712 - 168,540,897UniSTS
RH 3.4 Map4873.02UniSTS
Cytogenetic Map4q41UniSTS
Cytogenetic Map1q35UniSTS
RH143319  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21170,720,508 - 170,720,785 (-)MAPPERmRatBN7.2
mRatBN7.24139,703,268 - 139,703,543 (+)MAPPERmRatBN7.2
Rnor_6.01185,173,338 - 185,173,614NCBIRnor6.0
Rnor_6.04138,868,876 - 138,869,150NCBIRnor6.0
Rnor_5.04203,339,264 - 203,339,538UniSTSRnor5.0
Rnor_5.01192,145,110 - 192,145,386UniSTSRnor5.0
RGSC_v3.41174,575,270 - 174,575,546UniSTSRGSC3.4
RGSC_v3.44142,138,050 - 142,138,324UniSTSRGSC3.4
Celera4128,415,615 - 128,415,889UniSTS
Celera1168,540,721 - 168,540,997UniSTS
Cytogenetic Map4q41UniSTS
Cytogenetic Map1q35UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000027758   ⟹   ENSRNOP00000080338
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1170,721,272 - 170,722,576 (-)Ensembl
RefSeq Acc Id: XM_039101158   ⟹   XP_038957086
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81180,154,702 - 180,157,038 (-)NCBI
mRatBN7.21170,720,730 - 170,722,745 (-)NCBI
RefSeq Acc Id: XM_039101159   ⟹   XP_038957087
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81180,154,702 - 180,157,040 (-)NCBI
mRatBN7.21170,720,730 - 170,722,743 (-)NCBI
Protein Sequences
Protein RefSeqs XP_038957086 (Get FASTA)   NCBI Sequence Viewer  
  XP_038957087 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000080320.1
  ENSRNOP00000080338
  ENSRNOP00000080338.1
Reference Protein Sequences
RefSeq Acc Id: XP_038957086   ⟸   XM_039101158
- UniProtKB: A0A8I5ZQ33 (UniProtKB/TrEMBL),   A0A8I5ZPS5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038957087   ⟸   XM_039101159
- UniProtKB: A0A8I5ZQ33 (UniProtKB/TrEMBL),   A0A8I5ZPS5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000080338   ⟸   ENSRNOT00000027758
Protein Domains
Poly A polymerase head   tRNA nucleotidyltransferase/poly(A) polymerase RNA

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-57714 BioCyc
Ensembl Genes ENSRNOG00000006432 UniProtKB/TrEMBL
  ENSRNOG00000020477 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000027758.5 UniProtKB/TrEMBL
  ENSRNOT00000119654.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.460.10 UniProtKB/TrEMBL
  cca-adding enzyme, domain 2 UniProtKB/TrEMBL
InterPro NT_sf UniProtKB/TrEMBL
  PolA_pol_head_dom UniProtKB/TrEMBL
  PolyA_RNA-bd UniProtKB/TrEMBL
NCBI Gene LOC100911093 ENTREZGENE
PANTHER CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL UniProtKB/TrEMBL
  CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL UniProtKB/TrEMBL
Pfam PolyA_pol UniProtKB/TrEMBL
  PolyA_pol_RNAbd UniProtKB/TrEMBL
PhenoGen LOC100911093 PhenoGen
RatGTEx ENSRNOG00000006432 RatGTEx
  ENSRNOG00000020477 RatGTEx
Superfamily-SCOP Poly A polymerase C-terminal region-like UniProtKB/TrEMBL
  SSF81301 UniProtKB/TrEMBL
UniProt A0A8I5ZPS5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZQ33 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 LOC100911093  CCA tRNA nucleotidyltransferase 1, mitochondrial-like  AABR07005533.1    Data merged from RGD:15003492 737654 PROVISIONAL
2019-11-08 AABR07005533.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2012-07-05 LOC100911093  CCA tRNA nucleotidyltransferase 1, mitochondrial-like      Symbol and Name status set to provisional 70820 PROVISIONAL