Mtfr2 (mitochondrial fission regulator 2)

Gene: Mtfr2 (mitochondrial fission regulator 2) Rattus norvegicus

Analyze

Symbol:

Mtfr2

Name:

mitochondrial fission regulator 2

RGD ID:

6494892

Description:

Predicted to be involved in aerobic respiration and mitochondrial fission. Predicted to be located in mitochondrion. Orthologous to human MTFR2 (mitochondrial fission regulator 2); INTERACTS WITH diethylstilbestrol; fenvalerate; (-)-demecolcine (ortholog).

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

DUF729 domain containing 1; Dufd1; LOC100911069; protein FAM54A-like

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MTFR2 (mitochondrial fission regulator 2)	HGNC	HomoloGene, Inparanoid, NCBI, Panther, PhylomeDB
Mus musculus (house mouse):	Mtfr2 (mitochondrial fission regulator 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Mtfr2 (mitochondrial fission regulator 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MTFR2 (mitochondrial fission regulator 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MTFR2 (mitochondrial fission regulator 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mtfr2 (mitochondrial fission regulator 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MTFR2 (mitochondrial fission regulator 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MTFR2 (mitochondrial fission regulator 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mtfr2 (mitochondrial fission regulator 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Mtfr2 (mitochondrial fission regulator 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	MTFR2 (mitochondrial fission regulator 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	mtfr2 (mitochondrial fission regulator 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	mtfr2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	16,942,814 - 16,958,218 (+)	NCBI		GRCr8
mRatBN7.2	1	15,123,232 - 15,138,632 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	15,070,894 - 15,148,832 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	14,877,372 - 14,892,479 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	20,879,304 - 20,894,408 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	15,103,132 - 15,118,478 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	15,834,779 - 15,850,424 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	15,782,477 - 15,860,624 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	17,379,823 - 17,394,566 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	1	13,553,856 - 13,569,459 (+)	NCBI		Celera
Cytogenetic Map	1	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Familial Behcet-Like Autoinflammatory Syndrome (ISO)

genetic disease (ISO)

immunodeficiency 27A (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

azathioprine (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (ISO)

caffeine (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

dichloroacetic acid (ISO)

dicrotophos (ISO)

diethylstilbestrol (EXP)

dioxygen (ISO)

epoxiconazole (ISO)

fenvalerate (EXP)

FR900359 (ISO)

isobutanol (ISO)

lucanthone (ISO)

nickel atom (ISO)

ozone (ISO)

paracetamol (ISO)

perfluorononanoic acid (ISO)

quercetin (ISO)

resveratrol (ISO)

rotenone (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

temozolomide (ISO)

teriflunomide (ISO)

testosterone (ISO)

thalidomide (ISO)

Theaflavin 3,3'-digallate (ISO)

trimellitic anhydride (ISO)

triptonide (ISO)

trovafloxacin (ISO)

tungsten (ISO)

urethane (ISO)

valproic acid (ISO)

vincristine (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

aerobic respiration (IBA,IEA,ISO)

mitochondrial fission (IBA,IEA,ISO)

mitochondrion organization (ISO)

positive regulation of transcription by RNA polymerase II (IEA)

Cellular Component

mediator complex (IEA)

mitochondrion (IBA,IEA,ISO)

Molecular Function

protein binding (ISO)

transcription coregulator activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15489334	PMID:20568109

Genomics

Comparative Map Data

Mtfr2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	16,942,814 - 16,958,218 (+)	NCBI		GRCr8
mRatBN7.2	1	15,123,232 - 15,138,632 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	15,070,894 - 15,148,832 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	14,877,372 - 14,892,479 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	20,879,304 - 20,894,408 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	15,103,132 - 15,118,478 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	15,834,779 - 15,850,424 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	15,782,477 - 15,860,624 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	17,379,823 - 17,394,566 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	1	13,553,856 - 13,569,459 (+)	NCBI		Celera
Cytogenetic Map	1	p12	NCBI

MTFR2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	136,231,034 - 136,250,311 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	136,231,024 - 136,250,335 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	136,552,172 - 136,571,449 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	136,593,861 - 136,613,142 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	136,593,860 - 136,613,142	NCBI
Celera	6	137,292,609 - 137,311,889 (-)	NCBI		Celera
Cytogenetic Map	6	q23.3	NCBI
HuRef	6	134,116,804 - 134,136,084 (-)	NCBI		HuRef
CHM1_1	6	136,814,686 - 136,833,971 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	137,419,143 - 137,438,419 (-)	NCBI		T2T-CHM13v2.0

Mtfr2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	20,223,491 - 20,237,415 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	20,223,516 - 20,237,050 (+)	Ensembl		GRCm39 Ensembl
GRCm38	10	20,344,653 - 20,361,669 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	20,347,770 - 20,361,304 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	20,067,625 - 20,081,475 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	20,037,241 - 20,050,735 (+)	NCBI		MGSCv36	mm8
Celera	10	20,236,666 - 20,250,342 (+)	NCBI		Celera
Cytogenetic Map	10	A3	NCBI
cM Map	10	9.75	NCBI

Mtfr2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955439	646,432 - 663,033 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955439	643,289 - 662,921 (+)	NCBI	ChiLan1.0	ChiLan1.0

MTFR2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	156,201,929 - 156,226,277 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	154,100,726 - 154,124,456 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	133,995,679 - 134,014,947 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	138,085,517 - 138,104,764 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	138,084,908 - 138,104,740 (-)	Ensembl	panpan1.1		panPan2

MTFR2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	28,830,818 - 28,844,875 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	28,830,867 - 28,844,710 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	29,708,976 - 29,723,038 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	28,986,198 - 29,000,267 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	28,984,794 - 29,000,115 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	28,872,409 - 28,886,470 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	28,755,384 - 28,769,446 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	29,056,087 - 29,070,152 (-)	NCBI		UU_Cfam_GSD_1.0

Mtfr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	123,881,482 - 123,893,809 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936560	3,660,705 - 3,671,917 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936560	3,656,639 - 3,670,923 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MTFR2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	27,908,824 - 28,015,101 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	27,906,162 - 27,998,861 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	31,398,310 - 31,486,257 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MTFR2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	37,173,430 - 37,192,734 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	37,174,438 - 37,192,790 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	9,361,104 - 9,383,691 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mtfr2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624886	1,434,253 - 1,444,462 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624886	1,431,171 - 1,446,007 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Mtfr2
108 total Variants

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354647	Despr8	Despair related QTL 8		0.0000341	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	1	24744506	Rat
2298546	Neuinf4	Neuroinflammation QTL 4	5.1		nervous system integrity trait (VT:0010566)	spinal cord RT1-B protein level (CMO:0002132)	1	1	28736750	Rat
2313053	Bss51	Bone structure and strength QTL 51	3.8	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	1	32356093	Rat
2313070	Bss52	Bone structure and strength QTL 52	4.4	0.0001	body length (VT:0001256)	body length (CMO:0000013)	1	1	32356093	Rat
2313090	Bmd69	Bone mineral density QTL 69	4.4	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	1	32356093	Rat
738020	Pia8	Pristane induced arthritis QTL 8	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	1	65833076	Rat
1578650	Bmd6	Bone mineral density QTL 6	12.2		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	1	509108	43284926	Rat
1578651	Bmd7	Bone mineral density QTL 7	14.2		femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	1	509108	43284926	Rat
1578669	Bss9	Bone structure and strength QTL 9	6.3		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	1	509108	43284926	Rat
1554320	Bmd1	Bone mineral density QTL 1	12.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	509108	86060548	Rat
1600360	Mcs16	Mammary carcinoma susceptibility QTL 16	2.4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	1	2244390	43433040	Rat
7421626	Bp360	Blood pressure QTL 360		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	4393289	49393289	Rat
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	5925874	115540829	Rat
4889451	Eae29	Experimental allergic encephalomyelitis QTL 29	5.51		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	1	5925877	24697545	Rat
631508	Sald1	Serum aldosterone level QTL 1	3.7		blood aldosterone amount (VT:0005346)	serum aldosterone level (CMO:0000487)	1	9856001	54856001	Rat
2302038	Pia31	Pristane induced arthritis QTL 31	5.5	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	1	10992065	55992065	Rat
1300167	Hrtrt2	Heart rate QTL 2	4.35		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	11481312	75088344	Rat
2313062	Bmd73	Bone mineral density QTL 73	3.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	11481312	82174945	Rat
2313065	Bss67	Bone structure and strength QTL 67	3.1	0.0001	tibia area (VT:1000281)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
2313069	Bss68	Bone structure and strength QTL 68	2.9	0.0001	tibia size trait (VT:0100001)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
2313075	Bss66	Bone structure and strength QTL 66	3.4	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	11481312	82174945	Rat
2313077	Bss69	Bone structure and strength QTL 69	3.5	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	11481312	82174945	Rat
2313092	Bmd72	Bone mineral density QTL 72	2.5	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	11481312	82174945	Rat
2313097	Bss70	Bone structure and strength QTL 70	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
2317755	Glom22	Glomerulus QTL 22	3.8		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	1	11481482	32355910	Rat
1578756	Iddm22	Insulin dependent diabetes mellitus QTL 22	2.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	11835181	56835181	Rat

Markers in Region

RH132072

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	1	p12	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	41	56	40	19	40	8	10	74	35	41	11	8
Low		2	1	1		1		1
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001290110	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039103500	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063284133	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC159435	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000078589 ⟹ ENSRNOP00000068911

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	15,088,575 - 15,115,298 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000079069 ⟹ ENSRNOP00000072258

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	15,123,232 - 15,138,630 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000088025 ⟹ ENSRNOP00000071825

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	15,070,894 - 15,148,832 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000089966 ⟹ ENSRNOP00000072352

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	15,070,894 - 15,146,586 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000094509 ⟹ ENSRNOP00000097938

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	15,086,571 - 15,117,520 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000100188 ⟹ ENSRNOP00000076713

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	15,088,529 - 15,117,519 (+)	Ensembl

RefSeq Acc Id:

NM_001290110 ⟹ NP_001277039

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	16,942,814 - 16,958,214 (+)	NCBI
mRatBN7.2	1	15,123,232 - 15,138,632 (+)	NCBI
Rnor_6.0	1	15,834,779 - 15,850,424 (+)	NCBI
Celera	1	13,553,856 - 13,569,459 (+)	NCBI

Sequence:

show sequence

CGAGCGGTTCCGGTACGAAGTTGCTTGGCGGCTGTCGGCGGGCCGGCCGCCCCGCTTTGCGTCT
AGAGAGTTTCCCCGGCCGCCGGCGGCGTGCAATGCAGCGGGACGGTACCAACGAACAATGTTTT
CTTGAACTTGCTTCACCAATGTCTTTCATTCTGAATATATTAAGAAACATGCTGGCATATTTTG
GTGTTCCCGTAGATCAGGATTTGCTGATTTTTCAAAATAAAGATTATGGGTCAGCTCGGAGTAT
TGTCCGTGTTATTGGAAGAATGCTTCCTTTAGAGCCTTGCCGAAGACCTCGTTTTGAGTTGACC
CCACCTGCGAACGCTAAGGAGGTGGATGACTATGAACTTGCGGTTCCGTCTTTTGCTGATGTTT
TGTGTGTGGCAGATGATGGAGAAGCCGGTTGTCTCAGATTTCGACACAGTCTATGGAAAAAGGC
GGAAGGGAAAGCTGCTCTCTTCCATCCTTCAAAACTACCTTGGGACCTGTCGTCCCCTGCTCTA
AGTCAGAACAGAACAGTGGCCGATGACCTTCCTGTAAGCGAAGCTGCCATTAAAAAGATAGCCG
CCCTTGAAGATGAGCTGACTTCTCTCCGGGCTCAGATCGCGGCCATTGTGGCCATGCAGGACCT
GGGAGGGGGTGGGGAGACTGGCTTCATCAGCTTGAGCGATGGACCCAGCATGGAGCAGGTGCCA
CCATCATCAGCGACCGCTCGGCTGAGTGTGGAACCAGACCATGTTCCAAGTGTGGTGCTTTCTC
CTCCTCCCCTTCCTCCTCCTCCTCCCCCACTTCCTCCTCCTCAGTTTTCTCTGCAGCCTCCCAG
TTCTCTTCCCGTGCCACCCGGATCTGCGAATACACGTGGCATAGATAATCTGGCTGCTGAAATG
AAAAAGCGCCCTTCTGGTGTTAAGAAGACTGACGGCAGCCATCATTCAGAAAGCCAGAGAGTAA
GTGACGTTCCGAACATGTTGGATGTTCTGAAGGACATGAATAAGGTCAAACTTCGGCCAGTGGA
AAGGTCACCGGGTGGTAGACCCATTCAGAAGAGGAGAAGACAGAGTTCACAATGGGATCCAGTG
TCTCTAATTTCTAATGCACTGAAACAGAAGTTTGCCTTTCAAGATGATTCCTTTGATAGTGAAA
ATAGGTCTTGGCAAGGTTCTCCATTTTCTAGTCCAGAAACTTCCAGAAATGGTTCCAGGTTTTG
ACGTCACATTACTCCACCAGAGAGTCAGCGAGTGACCTAAGGGAAGGACCGATGATATAAAAGC
CGTAATCCAGGGTATCAGAAGCAAAAGCTGGACTACACTTGGAAGGACAGATCAGGCTTGCCCT
GTGGTATCCTTCACTGCCTGTCAGGGAATTACCACCTCTGTTAGGGTCATCAGGCTGTACTCTG
GGACCAGTATCCGCCCAGCCCGAGGAAGACATCTGTGAACACTGTCTCTGCTTTTGGAAGATGT
GGCATTTGACTGACTACTGAAAAGAGTTGGGTGTAGATTCCCCATATGAGTGCTACTGAAATAC
GTGGTTCCGTGATGTTCCTAAAACTATGGCTTCCTACGGAGGCTCCTTTCAGTCTTGTGAGTTG
CTGTGATACAGTTTACGTGGCTTTCAGTAACTTGTAGATTTCTTAGTGAGCAGAAGATGATGAT
TTTCATTAAGATAGAGTTTTAGTCACATAGGGCTGAACTTCCTAGAACTTCCTGCAGTAGTAAA
TTATTTGATCGTAAAGTACTACACGTAGAAGTAGACCCTTGATAGATTTCCTGCACACTGGCTT
TGCACACGCAGATGGCTTTGGTGTGTTCCCTTTGTTCTCTGTTATGTTTATAACCTGTATATAT
GTATATTCTTTTGTAAGTAGATTTTATAATAAATGGATCTTTTGAAAAAAAAAAAAAAAAAAAA
AAAAA

hide sequence

RefSeq Acc Id:

XM_039103500 ⟹ XP_038959428

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	16,949,195 - 16,958,218 (+)	NCBI
mRatBN7.2	1	15,129,992 - 15,138,322 (+)	NCBI

RefSeq Acc Id:

XM_063284133 ⟹ XP_063140203

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	16,949,079 - 16,958,218 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001277039	(Get FASTA)	NCBI Sequence Viewer
	XP_038959428	(Get FASTA)	NCBI Sequence Viewer
	XP_063140203	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI59436	(Get FASTA)	NCBI Sequence Viewer
	B0K035	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000068911.2
	ENSRNOP00000071825.2
	ENSRNOP00000072258
	ENSRNOP00000072258.1
	ENSRNOP00000072352.2
	ENSRNOP00055041048
	ENSRNOP00060005846
	ENSRNOP00065020861

RefSeq Acc Id:

NP_001277039 ⟸ NM_001290110

- UniProtKB:

B0K035 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MQRDGTNEQCFLELASPMSFILNILRNMLAYFGVPVDQDLLIFQNKDYGSARSIVRVIGRMLPL
EPCRRPRFELTPPANAKEVDDYELAVPSFADVLCVADDGEAGCLRFRHSLWKKAEGKAALFHPS
KLPWDLSSPALSQNRTVADDLPVSEAAIKKIAALEDELTSLRAQIAAIVAMQDLGGGGETGFIS
LSDGPSMEQVPPSSATARLSVEPDHVPSVVLSPPPLPPPPPPLPPPQFSLQPPSSLPVPPGSAN
TRGIDNLAAEMKKRPSGVKKTDGSHHSESQRVSDVPNMLDVLKDMNKVKLRPVERSPGGRPIQK
RRRQSSQWDPVSLISNALKQKFAFQDDSFDSENRSWQGSPFSSPETSRNGSRF

hide sequence

RefSeq Acc Id:	XP_038959428 ⟸ XM_039103500
- Peptide Label:	isoform X1

RefSeq Acc Id:

ENSRNOP00000072352 ⟸ ENSRNOT00000089966

RefSeq Acc Id:

ENSRNOP00000072258 ⟸ ENSRNOT00000079069

RefSeq Acc Id:

ENSRNOP00000071825 ⟸ ENSRNOT00000088025

RefSeq Acc Id:

ENSRNOP00000097938 ⟸ ENSRNOT00000094509

RefSeq Acc Id:

ENSRNOP00000068911 ⟸ ENSRNOT00000078589

RefSeq Acc Id:

ENSRNOP00000076713 ⟸ ENSRNOT00000100188

RefSeq Acc Id:	XP_063140203 ⟸ XM_063284133
- Peptide Label:	isoform X1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B0K035-F1-model_v2	AlphaFold	B0K035	1-373	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:6494892	AgrOrtholog
BioCyc Gene	G2FUF-62194	BioCyc
Ensembl Genes	ENSRNOG00000058050	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSRNOG00055028774	UniProtKB/Swiss-Prot
	ENSRNOG00060004654	UniProtKB/Swiss-Prot
	ENSRNOG00065015991	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000078589.2	UniProtKB/TrEMBL
	ENSRNOT00000079069	ENTREZGENE
	ENSRNOT00000079069.2	UniProtKB/Swiss-Prot
	ENSRNOT00000088025.2	UniProtKB/TrEMBL
	ENSRNOT00000089966.2	UniProtKB/TrEMBL
	ENSRNOT00055049850	UniProtKB/Swiss-Prot
	ENSRNOT00060007783	UniProtKB/Swiss-Prot
	ENSRNOT00065026587	UniProtKB/Swiss-Prot
InterPro	Mtfr1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	THRAP3_BCLAF1	UniProtKB/TrEMBL
KEGG Report	rno:100911069	UniProtKB/Swiss-Prot
NCBI Gene	LOC100911069	ENTREZGENE
PANTHER	MITOCHONDRIAL FISSION REGULATOR 2	UniProtKB/Swiss-Prot
	PTHR14215	UniProtKB/Swiss-Prot
	PTHR15268	UniProtKB/TrEMBL
	PTHR15268:SF4	UniProtKB/TrEMBL
Pfam	Mito_fiss_reg	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	THRAP3_BCLAF1	UniProtKB/TrEMBL
PhenoGen	Mtfr2	PhenoGen
RatGTEx	ENSRNOG00000058050	RatGTEx
	ENSRNOG00055028774	RatGTEx
	ENSRNOG00060004654	RatGTEx
	ENSRNOG00065015991	RatGTEx
UniProt	A0A0G2JU04_RAT	UniProtKB/TrEMBL
	A0A0G2K1G0_RAT	UniProtKB/TrEMBL
	A0A0G2K2S3_RAT	UniProtKB/TrEMBL
	B0K035	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-06-12	Mtfr2	mitochondrial fission regulator 2	LOC100911069	protein FAM54A-like	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-07-05	LOC100911069	protein FAM54A-like			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar