Gzmc-ps2 (granzyme C, pseudogene 2) - Rat Genome Database

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Gene: Gzmc-ps2 (granzyme C, pseudogene 2) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Gzmc-ps2
Name: granzyme C, pseudogene 2
RGD ID: 6494774
Description: Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis.
Type: pseudo (Ensembl: protein-coding)
RefSeq Status: MODEL
Previously known as: ENSRNOG00000069194; granzyme C-like; LOC100911163
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81534,359,939 - 34,370,593 (-)NCBIGRCr8
mRatBN7.21530,240,621 - 30,251,275 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1530,240,621 - 30,251,349 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl1530,240,621 - 30,251,349 (-)NCBImRatBN7.2 Ensembl
Rnor_6.01536,247,356 - 36,252,913 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01540,105,838 - 40,110,458 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1529,819,717 - 29,825,802 (-)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
proteolysis  (IEA)

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Gzmc-ps2
191 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15134723002Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)151985656634924750Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)151985656646187442Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000119796   ⟹   ENSRNOP00000078497
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1530,240,621 - 30,251,349 (-)Ensembl
RefSeq Acc Id: XM_003752807   ⟹   XP_003752855
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1529,819,717 - 29,825,802 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008770728   ⟹   XP_008768950
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01536,247,356 - 36,252,913 (-)NCBI
Sequence:
Protein Sequences
Ensembl Protein ENSRNOP00000078497.1
Reference Protein Sequences
RefSeq Acc Id: XP_003752855   ⟸   XM_003752807
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008768950   ⟸   XM_008770728
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000078497   ⟸   ENSRNOT00000119796
Protein Domains
Peptidase S1

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-13644 BioCyc
Ensembl Genes ENSRNOG00000069194 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000119796.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
InterPro Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/TrEMBL
NCBI Gene LOC100911163 ENTREZGENE
PANTHER GRANZYME C UniProtKB/TrEMBL
  KALLIKREIN-RELATED UniProtKB/TrEMBL
Pfam Trypsin UniProtKB/TrEMBL
PhenoGen Gzmc-ps2 PhenoGen
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
PROSITE TRYPSIN_DOM UniProtKB/TrEMBL
RatGTEx ENSRNOG00000069194 RatGTEx
SMART Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/TrEMBL
UniProt A0A8I6G1V5_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-10 Gzmc-ps2  granzyme C, pseudogene 2  LOC100911163  granzyme C-like  Symbol and Name Changed 1299863 APPROVED
2022-06-02 LOC100911163  granzyme C-like  ENSRNOG00000069194    Data merged from RGD:150342764 737654 PROVISIONAL
2021-08-31 ENSRNOG00000069194        Symbol and Name status set to provisional 45752 PROVISIONAL
2012-07-05 LOC100911163  granzyme C-like      Symbol and Name status set to provisional 70820 PROVISIONAL