Gene: Wnk4 (WNK lysine deficient protein kinase 4) Rattus norvegicus
Analyze
Symbol: Wnk4
Name: WNK lysine deficient protein kinase 4
Description: ENCODES a protein that exhibits protein serine/threonine kinase activity; ATP binding (ortholog); chloride channel inhibitor activity (ortholog); INVOLVED IN negative regulation of sodium ion transport; protein phosphorylation; chloride transport (ortholog); ASSOCIATED WITH autosomal dominant pseudohypoaldosteronism type 1 (ortholog); autosomal recessive pseudohypoaldosteronism type 1 (ortholog); Pseudohypoaldosteronism (ortholog); FOUND IN cytosol; membrane; bicellular tight junction (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 3,3',4,4',5-pentachlorobiphenyl; ammonium chloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ac2-059; Prkwnk4; protein kinase lysine-deficient 4; protein kinase with no lysine 4; protein kinase, lysine deficient 4; protein kinase, lysine-deficient 4; serine/threonine-protein kinase WNK4; WNK4 Ser/Thr kinase
Orthologs:
Homo sapiens (human) : WNK4 (WNK lysine deficient protein kinase 4)  HGNC  AGR
Mus musculus (house mouse) : Wnk4 (WNK lysine deficient protein kinase 4)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Wnk4 (WNK lysine deficient protein kinase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : WNK4 (WNK lysine deficient protein kinase 4)
Canis lupus familiaris (dog) : VPS25 (vacuolar protein sorting 25 homolog)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wnk4 (WNK lysine deficient protein kinase 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01089,181,139 - 89,198,213 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01088,979,661 - 88,997,344 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41090,289,273 - 90,306,225 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11090,303,667 - 90,320,558 (+)NCBI
Celera1084,920,709 - 84,937,662 (+)NCBI
Cytogenetic Map10q31NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Wnk4
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 631401
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE