Enables ionotropic glutamate receptor binding activity and protein phosphatase 2B binding activity. Predicted to be involved in several processes, including neurotransmitter receptor transport, postsynaptic endosome to lysosome; positive regulation of glutamatergic synaptic transmission; and postsynaptic neurotransmitter receptor diffusion trapping. Located in dendrite membrane and postsynaptic membrane. Part of AMPA glutamate receptor complex. Is active in glutamatergic synapse and postsynaptic density membrane. Orthologous to human CACNG8 (calcium voltage-gated channel auxiliary subunit gamma 8); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; dilated cardiomyopathy pathway; hypertrophic cardiomyopathy pathway; INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; ammonium chloride.
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CACNG8 mRNA
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CACNG8 mRNA
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CACNG8 mRNA
[Toluene co-treated with Xylenes co-treated with ethylbenzene] results in decreased expression of CACNG8 mRNA and [Toluene co-treated with Xylenes co-treated with ethylbenzene] results in increased methylation of CACNG8 gene
[Toluene co-treated with Xylenes co-treated with ethylbenzene] results in decreased expression of CACNG8 mRNA and [Toluene co-treated with Xylenes co-treated with ethylbenzene] results in increased methylation of CACNG8 gene
Patients with Dilated Cardiomyopathy and Sustained Monomorphic Ventricular Tachycardia Show Up-Regulation of KCNN3 and KCNJ2 Genes and CACNG8-Linked Left Ventricular Dysfunction.
