Wfdc2 (WAP four-disulfide core domain 2) - Rat Genome Database

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Gene: Wfdc2 (WAP four-disulfide core domain 2) Rattus norvegicus
Analyze
Symbol: Wfdc2
Name: WAP four-disulfide core domain 2
RGD ID: 628757
Description: Predicted to enable aspartic-type endopeptidase inhibitor activity and serine-type endopeptidase inhibitor activity. Predicted to be involved in antibacterial humoral response and innate immune response. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human WFDC2 (WAP four-disulfide core domain 2); INTERACTS WITH 1-benzylpiperazine; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: epididymal secretory protein 4; re4; WAP four-disulfide core domain protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83173,706,091 - 173,735,055 (+)NCBIGRCr8
mRatBN7.23153,286,946 - 153,314,832 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3153,286,131 - 153,292,807 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3157,097,084 - 157,102,772 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03165,596,050 - 165,601,738 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03163,339,688 - 163,345,374 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03161,018,497 - 161,045,469 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3161,018,511 - 161,024,209 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03167,197,728 - 167,203,406 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43155,582,378 - 155,588,056 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13155,488,413 - 155,494,091 (+)NCBI
Celera3151,896,564 - 151,902,242 (+)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-benzylpiperazine  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,6-dinitrotoluene  (EXP)
3,7-dihydropurine-6-thione  (EXP)
3-chloropropane-1,2-diol  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP,ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
asbestos  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
calcitriol  (ISO)
camptothecin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
chromium(6+)  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
diazinon  (ISO)
diethylstilbestrol  (ISO)
diquat  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
elemental selenium  (ISO)
entinostat  (ISO)
ethanol  (ISO)
fentin chloride  (EXP)
fonofos  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glycidol  (ISO)
heptachlor  (EXP)
inulin  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
mercaptopurine  (EXP)
mercury dibromide  (ISO)
methapyrilene  (EXP)
methimazole  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (EXP)
Nutlin-3  (ISO)
ozone  (ISO)
panobinostat  (ISO)
parathion  (ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
propiconazole  (ISO)
purine-6-thiol  (EXP)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
tamoxifen  (ISO)
Tanshinone I  (ISO)
tebuconazole  (ISO)
terbufos  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
toluene  (EXP)
trichostatin A  (ISO)
uranium atom  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Information Derived from GenBank Report RGD, Sept. 2003
Additional References at PubMed
PMID:23376485   PMID:23533145   PMID:33903172  


Genomics

Comparative Map Data
Wfdc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83173,706,091 - 173,735,055 (+)NCBIGRCr8
mRatBN7.23153,286,946 - 153,314,832 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3153,286,131 - 153,292,807 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3157,097,084 - 157,102,772 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03165,596,050 - 165,601,738 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03163,339,688 - 163,345,374 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03161,018,497 - 161,045,469 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3161,018,511 - 161,024,209 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03167,197,728 - 167,203,406 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43155,582,378 - 155,588,056 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13155,488,413 - 155,494,091 (+)NCBI
Celera3151,896,564 - 151,902,242 (+)NCBICelera
Cytogenetic Map3q42NCBI
WFDC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382045,469,753 - 45,481,532 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2045,469,753 - 45,481,532 (+)EnsemblGRCh38hg38GRCh38
GRCh372044,098,393 - 44,110,172 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362043,531,808 - 43,543,586 (+)NCBINCBI36Build 36hg18NCBI36
Build 342043,531,807 - 43,541,802NCBI
Celera2040,806,906 - 40,818,684 (+)NCBICelera
Cytogenetic Map20q13.12NCBI
HuRef2040,839,873 - 40,851,651 (+)NCBIHuRef
CHM1_12044,000,939 - 44,012,717 (+)NCBICHM1_1
T2T-CHM13v2.02047,205,608 - 47,217,387 (+)NCBIT2T-CHM13v2.0
Wfdc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392164,404,635 - 164,410,430 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2164,404,333 - 164,410,430 (+)EnsemblGRCm39 Ensembl
GRCm382164,562,715 - 164,568,510 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2164,562,413 - 164,568,510 (+)EnsemblGRCm38mm10GRCm38
MGSCv372164,388,216 - 164,394,006 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362165,511,843 - 165,517,633 (+)NCBIMGSCv36mm8
MGSCv362164,253,921 - 164,259,711 (+)NCBIMGSCv36mm8
Celera2170,502,300 - 170,504,943 (+)NCBICelera
Cytogenetic Map2H3NCBI
cM Map285.2NCBI
Wfdc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544511,721,674 - 11,730,302 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544511,723,634 - 11,730,304 (-)NCBIChiLan1.0ChiLan1.0
WFDC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22151,206,129 - 51,217,927 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12051,199,239 - 51,211,036 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02041,803,624 - 41,815,442 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12042,893,345 - 42,905,122 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2042,893,345 - 42,905,122 (+)Ensemblpanpan1.1panPan2
WFDC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12432,759,763 - 32,764,620 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2432,759,696 - 32,764,620 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2432,404,009 - 32,409,500 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02433,469,523 - 33,475,041 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2433,469,535 - 33,475,038 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12432,730,648 - 32,736,145 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02432,846,352 - 32,851,837 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02433,390,607 - 33,396,114 (+)NCBIUU_Cfam_GSD_1.0
Wfdc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640191,962,842 - 191,968,722 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365147,416,460 - 7,422,366 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365147,416,484 - 7,422,306 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WFDC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1747,816,452 - 47,824,087 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11747,816,452 - 47,824,087 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21753,365,583 - 53,366,448 (-)NCBISscrofa10.2Sscrofa10.2susScr3
WFDC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1218,351,063 - 18,361,893 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl218,351,043 - 18,361,868 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605066,992,165 - 67,003,862 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wfdc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247908,928,002 - 8,934,503 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Wfdc2
106 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:167
Count of miRNA genes:103
Interacting mature miRNAs:108
Transcripts:ENSRNOT00000019804, ENSRNOT00000039664
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145925360166177555Rat
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3145925360166177555Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145956084157309487Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3145925360166177555Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3145925360166177555Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3145925360166177555Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141074471169034231Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3145925360166177555Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3145956084169034231Rat
61335Bp20Blood pressure QTL 203arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141339236155617360Rat
2317883Alcrsp26Alcohol response QTL 261.80.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)3145526770169034231Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141339013162184794Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3145956084161299569Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3121056165157309487Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3130193298161695983Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3149040888168026850Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3138799500169034231Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3145925360166177555Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_173109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001837031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001837032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005501791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005501792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005501795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005501796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005501797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005501798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010064571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010064572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AJ515239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ515241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000019804   ⟹   ENSRNOP00000019804
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3153,287,130 - 153,292,807 (+)Ensembl
Rnor_6.0 Ensembl3161,018,511 - 161,024,209 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000039664   ⟹   ENSRNOP00000032197
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3153,287,557 - 153,292,807 (+)Ensembl
Rnor_6.0 Ensembl3161,018,538 - 161,024,138 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110333   ⟹   ENSRNOP00000077787
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3153,286,131 - 153,292,766 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119981   ⟹   ENSRNOP00000082683
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3153,287,130 - 153,290,306 (+)Ensembl
RefSeq Acc Id: NM_173109   ⟹   NP_775132
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83173,706,475 - 173,712,153 (+)NCBI
mRatBN7.23153,287,130 - 153,292,808 (+)NCBI
Rnor_6.03161,018,502 - 161,024,180 (+)NCBI
Rnor_5.03167,197,728 - 167,203,406 (+)NCBI
RGSC_v3.43155,582,378 - 155,588,056 (+)RGD
Celera3151,896,564 - 151,902,242 (+)RGD
Sequence:
RefSeq Acc Id: XM_039104401   ⟹   XP_038960329
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83173,706,091 - 173,712,163 (+)NCBI
mRatBN7.23153,287,088 - 153,292,818 (+)NCBI
RefSeq Acc Id: XM_063283178   ⟹   XP_063139248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83173,707,282 - 173,712,163 (+)NCBI
RefSeq Acc Id: XR_001837032
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83173,706,133 - 173,735,055 (+)NCBI
mRatBN7.23153,287,088 - 153,314,832 (+)NCBI
Rnor_6.03161,018,497 - 161,045,469 (+)NCBI
Sequence:
RefSeq Acc Id: XR_005501791
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83173,706,133 - 173,735,055 (+)NCBI
mRatBN7.23153,287,088 - 153,314,832 (+)NCBI
RefSeq Acc Id: XR_005501792
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83173,706,133 - 173,735,055 (+)NCBI
mRatBN7.23153,287,088 - 153,314,832 (+)NCBI
RefSeq Acc Id: XR_005501795
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83173,706,133 - 173,735,055 (+)NCBI
mRatBN7.23153,287,047 - 153,314,832 (+)NCBI
RefSeq Acc Id: XR_005501796
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83173,706,133 - 173,735,055 (+)NCBI
mRatBN7.23153,287,048 - 153,314,832 (+)NCBI
RefSeq Acc Id: XR_005501797
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83173,706,133 - 173,735,055 (+)NCBI
mRatBN7.23153,287,048 - 153,314,832 (+)NCBI
RefSeq Acc Id: XR_005501798
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83173,706,133 - 173,735,055 (+)NCBI
mRatBN7.23153,287,048 - 153,314,832 (+)NCBI
RefSeq Acc Id: XR_010064571
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83173,706,133 - 173,735,055 (+)NCBI
RefSeq Acc Id: XR_010064572
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83173,706,133 - 173,735,055 (+)NCBI
RefSeq Acc Id: NP_775132   ⟸   NM_173109
- Peptide Label: precursor
- UniProtKB: Q8CHN1 (UniProtKB/Swiss-Prot),   Q8CHN3 (UniProtKB/Swiss-Prot),   A6JX96 (UniProtKB/TrEMBL),   A0A8L2Q9W6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000019804   ⟸   ENSRNOT00000019804
Ensembl Acc Id: ENSRNOP00000032197   ⟸   ENSRNOT00000039664
RefSeq Acc Id: XP_038960329   ⟸   XM_039104401
- Peptide Label: isoform X2
- UniProtKB: A6JX97 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000082683   ⟸   ENSRNOT00000119981
Ensembl Acc Id: ENSRNOP00000077787   ⟸   ENSRNOT00000110333
RefSeq Acc Id: XP_063139248   ⟸   XM_063283178
- Peptide Label: isoform X1
Protein Domains
WAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8CHN3-F1-model_v2 AlphaFold Q8CHN3 1-168 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692657
Promoter ID:EPDNEW_R3181
Type:multiple initiation site
Name:Wfdc2_1
Description:WAP four-disulfide core domain 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03161,018,527 - 161,018,587EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628757 AgrOrtholog
BioCyc Gene G2FUF-46849 BioCyc
Ensembl Genes ENSRNOG00000014739 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019804.9 UniProtKB/TrEMBL
  ENSRNOT00000039664.6 UniProtKB/TrEMBL
  ENSRNOT00000110333.1 UniProtKB/Swiss-Prot
  ENSRNOT00000119981.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.75.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Elafin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WAP_four-disulfide_core UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:286888 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 286888 ENTREZGENE
PANTHER WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WHEY ACDIC PROTEIN WAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam WAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Wfdc2 PhenoGen
PRINTS 4DISULPHCORE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE WAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014739 RatGTEx
SMART WAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57256 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZTZ2_RAT UniProtKB/TrEMBL
  A0A8L2Q9W6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QHW6_RAT UniProtKB/TrEMBL
  A6JX96 ENTREZGENE, UniProtKB/TrEMBL
  A6JX97 ENTREZGENE, UniProtKB/TrEMBL
  A6JX98_RAT UniProtKB/TrEMBL
  Q8CHN1 ENTREZGENE
  Q8CHN3 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q8CHN1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Wfdc2  WAP four-disulfide core domain 2  re4  epididymal secretory protein 4  Symbol and Name updated 1299863 APPROVED
2003-02-27 re4  epididymal secretory protein 4      Symbol and Name status set to provisional 70820 PROVISIONAL