Gene: Lgi1 (leucine-rich, glioma inactivated 1) Rattus norvegicus
Symbol: Lgi1
Name: leucine-rich, glioma inactivated 1
Description: ENCODES a protein that exhibits receptor binding (ortholog); INVOLVED IN positive regulation of synaptic transmission; protein homooligomerization; axon guidance (ortholog); ASSOCIATED WITH increased susceptibility to induction of seizure by inducing agent; premature death; ASSOCIATED WITH Epilepsy; epilepsy; Epilepsy, Familial Temporal Lobe, 1 (ortholog); FOUND IN extracellular space; synapse; INTERACTS WITH 6-propyl-2-thiouracil; all-trans-retinoic acid; ammonium chloride
Type: protein-coding
Also known as: leucine-rich glioma-inactivated protein 1; leucine-rich glioma-inactivated protein 1-like; leucine-rich repeat LGI family, member 1; MGC105310
Homo sapiens (human) : LGI1 (leucine rich glioma inactivated 1)  HGNC  AGR
Mus musculus (house mouse) : Lgi1 (leucine-rich repeat LGI family, member 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Lgi1 (leucine rich glioma inactivated 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LGI1 (leucine rich glioma inactivated 1)
Canis lupus familiaris (dog) : LGI1 (leucine rich glioma inactivated 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lgi1 (leucine rich glioma inactivated 1)
more info ...
Allele / Splice: Lgi1m1Kyo  
Genetic Models: F344-Lgi1m1Kyo
Is Marker For: Strains:   F344.NER-(D1Mgh6-D1Rat73)(D5Mgh4-D5Rat36)Lgi1m1/Kyo   F344-Lgi1m1Kyo  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01256,955,944 - 256,996,835 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01264,436,441 - 264,477,332 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41242,593,236 - 242,634,141 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11242,809,453 - 242,810,274 (+)NCBI
Celera1233,136,652 - 233,177,516 (+)NCBICelera
Cytogenetic Map1q53NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Lgi1
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 628742
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE