Gene: Dkc1 (dyskerin pseudouridine synthase 1) Rattus norvegicus
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Symbol: Dkc1
Name: dyskerin pseudouridine synthase 1
Description: ENCODES a protein that exhibits box H/ACA snoRNA binding (ortholog); RNA binding (ortholog); telomerase activity (ortholog); INVOLVED IN positive regulation of cell proliferation; snoRNA guided rRNA pseudouridine synthesis; box H/ACA snoRNA metabolic process (ortholog); PARTICIPATES IN ribosome biogenesis pathway; ASSOCIATED WITH Anemia (ortholog); anemia (ortholog); Anemia, Aplastic (ortholog); FOUND IN box H/ACA snoRNP complex; Cajal body; nucleolus; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: dyskeratosis congenita 1, dyskerin; dyskerin; h/ACA ribonucleoprotein complex subunit 4; Nap57; nopp140-associated protein of 57 kDa; nucleolar protein family A member 4; nucleolar protein NAP57; snoRNP protein DKC1
Orthologs:
Homo sapiens (human) : DKC1 (dyskerin pseudouridine synthase 1)  HGNC
Mus musculus (house mouse) : Dkc1 (dyskeratosis congenita 1, dyskerin)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Dkc1 (dyskerin pseudouridine synthase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DKC1 (dyskerin pseudouridine synthase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dkc1 (dyskerin pseudouridine synthase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X155,844,914 - 155,862,363 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01151,564,354 - 151,578,635 (-)NCBIRnor5.0rn5Rnor5.0
Celera1135,295,501 - 135,310,658 (-)ENTREZGENE
Cytogenetic MapXq37NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Dkc1
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RGD Object Information
RGD ID: 621780
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-06-06
Status: ACTIVE