Grip1 (glutamate receptor interacting protein 1) - Rat Genome Database

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Gene: Grip1 (glutamate receptor interacting protein 1) Rattus norvegicus
Analyze
Symbol: Grip1
Name: glutamate receptor interacting protein 1
RGD ID: 621667
Description: Enables GTPase binding activity; PDZ domain binding activity; and ionotropic glutamate receptor binding activity. Involved in several processes, including cellular response to brain-derived neurotrophic factor stimulus; nervous system development; and positive regulation of cell projection organization. Located in several cellular components, including dendrite; spine synapse; and synaptic membrane. Part of exocyst. Is active in glutamatergic synapse and postsynaptic density. Human ortholog(s) of this gene implicated in Fraser syndrome 3. Orthologous to human GRIP1 (glutamate receptor interacting protein 1); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-Tetrachlorodibenzofuran; 2,3-Dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: AMPA receptor-interacting protein GRIP1; Glutamate receptor interacting protein; glutamate receptor-interacting protein 1; GRIP-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8756,820,501 - 57,477,877 (+)NCBIGRCr8
mRatBN7.2754,934,856 - 55,592,274 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl754,934,250 - 55,592,273 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx757,218,667 - 57,489,247 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0759,421,818 - 59,692,413 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0759,199,652 - 59,469,780 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0764,672,723 - 64,854,939 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl764,672,722 - 64,864,404 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0764,890,319 - 65,072,097 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4759,157,276 - 59,306,131 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1759,170,845 - 59,326,858 (+)NCBI
Celera752,073,046 - 52,340,208 (+)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,4,5-tetrachlorophenol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,3-Dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acetohydrazide  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
amiloride  (ISO)
amitrole  (EXP)
androgen antagonist  (EXP)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
butanal  (ISO)
Butylparaben  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cannabidiol  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
cocaine  (EXP,ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
DDE  (EXP)
dibutyl phthalate  (EXP)
doxorubicin  (ISO)
entinostat  (ISO)
enzacamene  (EXP)
epoxiconazole  (EXP)
ethanol  (EXP)
folic acid  (ISO)
FR900359  (ISO)
genistein  (ISO)
L-methionine  (ISO)
linuron  (EXP)
methimazole  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
O-methyleugenol  (ISO)
ozone  (ISO)
paracetamol  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
phenobarbital  (EXP)
pirinixic acid  (ISO)
PK-11195  (ISO)
potassium chromate  (ISO)
prochloraz  (EXP)
procymidone  (EXP)
rac-lactic acid  (ISO)
sulfadimethoxine  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Postsynaptic ephrinB3 promotes shaft glutamatergic synapse formation. Aoto J, etal., J Neurosci. 2007 Jul 11;27(28):7508-19. doi: 10.1523/JNEUROSCI.0705-07.2007.
2. A novel Wnt5a-Frizzled4 signaling pathway mediates activity-independent dendrite morphogenesis via the distal PDZ motif of Frizzled 4. Bian WJ, etal., Dev Neurobiol. 2015 Aug;75(8):805-22. doi: 10.1002/dneu.22250. Epub 2014 Dec 1.
3. PIKE-mediated PI3-kinase activity is required for AMPA receptor surface expression. Chan CB, etal., EMBO J. 2011 Aug 16;30(20):4274-86. doi: 10.1038/emboj.2011.281.
4. A four PDZ domain-containing splice variant form of GRIP1 is localized in GABAergic and glutamatergic synapses in the brain. Charych EI, etal., J Biol Chem. 2004 Sep 10;279(37):38978-90. doi: 10.1074/jbc.M405786200. Epub 2004 Jun 29.
5. Identification and characterization of two novel splice forms of GRIP1 in the rat brain. Charych EI, etal., J Neurochem. 2006 May;97(3):884-98. doi: 10.1111/j.1471-4159.2006.03795.x. Epub 2006 Mar 15.
6. Phosphorylation of the AMPA receptor subunit GluR2 differentially regulates its interaction with PDZ domain-containing proteins. Chung HJ, etal., J Neurosci. 2000 Oct 1;20(19):7258-67.
7. Differential palmitoylation directs the AMPA receptor-binding protein ABP to spines or to intracellular clusters. DeSouza S, etal., J Neurosci 2002 May 1;22(9):3493-503.
8. Characterization of the glutamate receptor-interacting proteins GRIP1 and GRIP2. Dong H, etal., J Neurosci 1999 Aug 15;19(16):6930-41.
9. GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors. Dong H, etal., Nature 1997 Mar 20;386(6622):279-84.
10. PDZ7 of glutamate receptor interacting protein binds to its target via a novel hydrophobic surface area. Feng W, etal., J Biol Chem 2002 Oct 25;277(43):41140-6.
11. Association of the AMPA receptor-related postsynaptic density proteins GRIP and ABP with subsets of glutamate-sensitive neurons in the rat retina. Gabriel R, etal., J Comp Neurol 2002 Jul 22;449(2):129-40.
12. Activity-dependent synaptic GRIP1 accumulation drives synaptic scaling up in response to action potential blockade. Gainey MA, etal., Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):E3590-9. doi: 10.1073/pnas.1510754112. Epub 2015 Jun 24.
13. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
14. Glutamate stimulates glutamate receptor interacting protein 1 degradation by ubiquitin-proteasome system to regulate surface expression of GluR2. Guo L and Wang Y, Neuroscience. 2007 Mar 2;145(1):100-9. doi: 10.1016/j.neuroscience.2006.11.042. Epub 2007 Jan 3.
15. The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs. Hirbec H, etal., J Biol Chem. 2002 May 3;277(18):15221-4. Epub 2002 Mar 12.
16. Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP. Hirbec H, etal., Neuron. 2003 Feb 20;37(4):625-38. doi: 10.1016/s0896-6273(02)01191-1.
17. CASK associates with glutamate receptor interacting protein and signaling molecules. Hong CJ and Hsueh YP, Biochem Biophys Res Commun. 2006 Dec 22;351(3):771-6. Epub 2006 Oct 30.
18. GRIP1 controls dendrite morphogenesis by regulating EphB receptor trafficking. Hoogenraad CC, etal., Nat Neurosci. 2005 Jul;8(7):906-15. doi: 10.1038/nn1487.
19. Roles that nurses in the community can play in nursing research. Johnson MN and Okunade AO, Int Nurs Rev. 1975 Sep-Oct;22(5):147-9.
20. Acute BDNF treatment upregulates GluR1-SAP97 and GluR2-GRIP1 interactions: implications for sustained AMPA receptor expression. Jourdi H and Kabbaj M, PLoS One. 2013;8(2):e57124. doi: 10.1371/journal.pone.0057124. Epub 2013 Feb 27.
21. Brain-derived neurotrophic factor signal enhances and maintains the expression of AMPA receptor-associated PDZ proteins in developing cortical neurons. Jourdi H, etal., Dev Biol. 2003 Nov 15;263(2):216-30. doi: 10.1016/j.ydbio.2003.07.008.
22. The GIT family of proteins forms multimers and associates with the presynaptic cytomatrix protein Piccolo. Kim S, etal., J Biol Chem. 2003 Feb 21;278(8):6291-300. Epub 2002 Dec 6.
23. Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting. Ko J, etal., J Neurosci. 2003 Mar 1;23(5):1667-77.
24. CIPP, a novel multivalent PDZ domain protein, selectively interacts with Kir4.0 family members, NMDA receptor subunits, neurexins, and neuroligins. Kurschner C, etal., Mol Cell Neurosci. 1998 Jun;11(3):161-72.
25. GRIP1 in GABAergic synapses. Li RW, etal., J Comp Neurol. 2005 Jul 18;488(1):11-27.
26. PICK1 interacts with ABP/GRIP to regulate AMPA receptor trafficking. Lu W and Ziff EB, Neuron. 2005 Aug 4;47(3):407-21.
27. GRIP1 and 2 regulate activity-dependent AMPA receptor recycling via exocyst complex interactions. Mao L, etal., Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19038-43. doi: 10.1073/pnas.1013494107. Epub 2010 Oct 18.
28. NMDA receptor activation potentiates inhibitory transmission through GABA receptor-associated protein-dependent exocytosis of GABA(A) receptors. Marsden KC, etal., J Neurosci. 2007 Dec 26;27(52):14326-37.
29. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
30. Generation of lentiviral transgenic rats expressing glutamate receptor interacting protein 1 (GRIP1) in brain, spinal cord and testis. Nakagawa T, etal., J Neurosci Methods. 2006 Apr 15;152(1-2):1-9. doi: 10.1016/j.jneumeth.2005.08.001. Epub 2005 Sep 12.
31. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
32. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
33. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
34. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
35. Novel anchorage of GluR2/3 to the postsynaptic density by the AMPA receptor-binding protein ABP. Srivastava S, etal., Neuron 1998 Sep;21(3):581-91.
36. Interactions between NEEP21, GRIP1 and GluR2 regulate sorting and recycling of the glutamate receptor subunit GluR2. Steiner P, etal., EMBO J. 2005 Aug 17;24(16):2873-84. Epub 2005 Jul 21.
37. GRIP1 is required for homeostatic regulation of AMPAR trafficking. Tan HL, etal., Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):10026-31. doi: 10.1073/pnas.1512786112. Epub 2015 Jul 27.
38. Ribosomal S6 kinase 2 interacts with and phosphorylates PDZ domain-containing proteins and regulates AMPA receptor transmission. Thomas GM, etal., Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15006-11. Epub 2005 Oct 10.
39. Interaction between GRIP and liprin-alpha/SYD2 is required for AMPA receptor targeting. Wyszynski M, etal., Neuron 2002 Mar 28;34(1):39-52.
40. GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex. Ye B, etal., Neuron 2000 Jun;26(3):603-17.
41. Gephyrin interacts with the glutamate receptor interacting protein 1 isoforms at GABAergic synapses. Yu W, etal., J Neurochem. 2008 Jun 1;105(6):2300-14. doi: 10.1111/j.1471-4159.2008.05311.x.
42. The AAA+ ATPase Thorase regulates AMPA receptor-dependent synaptic plasticity and behavior. Zhang J, etal., Cell. 2011 Apr 15;145(2):284-99. doi: 10.1016/j.cell.2011.03.016.
Additional References at PubMed
PMID:10197531   PMID:10414981   PMID:11178875   PMID:12458226   PMID:14730302   PMID:15207857   PMID:15458844   PMID:15684087   PMID:15750591   PMID:15769988   PMID:15895086   PMID:16344550  
PMID:17110338   PMID:17121843   PMID:19534762   PMID:20837103   PMID:22342749   PMID:22980744   PMID:28821652  


Genomics

Comparative Map Data
Grip1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8756,820,501 - 57,477,877 (+)NCBIGRCr8
mRatBN7.2754,934,856 - 55,592,274 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl754,934,250 - 55,592,273 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx757,218,667 - 57,489,247 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0759,421,818 - 59,692,413 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0759,199,652 - 59,469,780 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0764,672,723 - 64,854,939 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl764,672,722 - 64,864,404 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0764,890,319 - 65,072,097 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4759,157,276 - 59,306,131 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1759,170,845 - 59,326,858 (+)NCBI
Celera752,073,046 - 52,340,208 (+)NCBICelera
Cytogenetic Map7q22NCBI
GRIP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381266,347,431 - 67,069,338 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1266,347,431 - 67,069,162 (-)EnsemblGRCh38hg38GRCh38
GRCh371266,741,211 - 67,463,118 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361265,029,066 - 65,359,020 (-)NCBINCBI36Build 36hg18NCBI36
Build 341265,028,871 - 65,145,401NCBI
Celera1266,405,432 - 66,737,052 (-)NCBICelera
Cytogenetic Map12q14.3NCBI
HuRef1263,792,018 - 64,123,720 (-)NCBIHuRef
CHM1_11266,708,221 - 67,039,968 (-)NCBICHM1_1
T2T-CHM13v2.01266,326,883 - 67,048,770 (-)NCBIT2T-CHM13v2.0
Grip1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910119,289,810 - 119,923,172 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10119,289,735 - 119,923,166 (+)EnsemblGRCm39 Ensembl
GRCm3810119,453,238 - 120,087,267 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10119,453,830 - 120,087,261 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710118,891,370 - 119,512,653 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610118,857,374 - 119,478,657 (+)NCBIMGSCv36mm8
Celera10121,814,033 - 122,436,941 (+)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1067.33NCBI
Grip1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545812,967,089 - 13,214,838 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545812,970,858 - 13,179,369 (-)NCBIChiLan1.0ChiLan1.0
GRIP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21027,286,061 - 28,012,479 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11227,282,825 - 28,004,487 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01221,841,611 - 22,562,418 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11222,826,257 - 23,069,480 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1222,744,177 - 23,069,480 (+)Ensemblpanpan1.1panPan2
GRIP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1108,801,023 - 9,187,684 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl108,802,529 - 9,063,848 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha108,731,329 - 9,389,361 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0108,912,752 - 9,572,589 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl108,914,210 - 9,176,615 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1108,789,226 - 9,449,620 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0109,034,586 - 9,695,263 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0109,155,858 - 9,816,627 (-)NCBIUU_Cfam_GSD_1.0
Grip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494549,107,221 - 49,757,054 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365454,353,040 - 5,002,725 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365454,353,056 - 4,606,196 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GRIP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl530,697,040 - 31,020,901 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1530,697,018 - 31,175,412 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2533,972,164 - 34,714,229 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GRIP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11162,018,037 - 62,464,440 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1162,015,463 - 62,335,876 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037182,985,387 - 183,705,463 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Grip1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248021,264,833 - 1,964,202 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248021,558,364 - 1,954,695 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Grip1
4415 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:195
Count of miRNA genes:111
Interacting mature miRNAs:139
Transcripts:ENSRNOT00000005539, ENSRNOT00000005545, ENSRNOT00000064448
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72673740163902784Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)72940968374409683Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73111283276112832Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73429328279293282Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73429328279293282Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73796056982960569Rat
2303629Vencon3Ventilatory control QTL 37.25respiration trait (VT:0001943)respiration rate (CMO:0000289)74110969256793354Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74659007091590070Rat
10059605Kidm47Kidney mass QTL 472.910.05kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)74725178365728867Rat
2293696Bmd32Bone mineral density QTL 325.10.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)74765143992651439Rat
2293707Bss32Bone structure and strength QTL 327.640.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)74765143992651439Rat
2300178Bmd54Bone mineral density QTL 545.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)74765143992651439Rat
2293644Bmd29Bone mineral density QTL 295.40.0001femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)74765143992651439Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
2293685Bmd21Bone mineral density QTL 214.20.0003femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)74765143992651439Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)753612714103945643Rat

Markers in Region
D7Got206  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2755,393,141 - 55,393,316 (+)MAPPERmRatBN7.2
Rnor_6.0114,611,841 - 14,612,015NCBIRnor6.0
Rnor_6.0764,669,331 - 64,669,505NCBIRnor6.0
Rnor_5.0764,886,927 - 64,887,101UniSTSRnor5.0
Rnor_5.0116,161,696 - 16,161,870UniSTSRnor5.0
Celera752,155,851 - 52,156,025UniSTS
Cytogenetic Map7q22UniSTS
AW530851  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2755,551,489 - 55,551,685 (+)MAPPERmRatBN7.2
Rnor_6.0764,826,962 - 64,827,157NCBIRnor6.0
Rnor_5.0765,044,120 - 65,044,315UniSTSRnor5.0
RGSC_v3.4759,274,596 - 59,274,791UniSTSRGSC3.4
Celera752,312,966 - 52,313,161UniSTS
RH 3.4 Map7489.8UniSTS
Cytogenetic Map7q22UniSTS
AU049021  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2755,414,629 - 55,414,796 (+)MAPPERmRatBN7.2
Rnor_6.0764,690,095 - 64,690,261NCBIRnor6.0
Rnor_5.0764,908,037 - 64,908,203UniSTSRnor5.0
Celera752,177,253 - 52,177,419UniSTS
Cytogenetic Map7q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 54 8 16
Low 1 24 31 18 12 18 20 27 23 8
Below cutoff 2 10 19 16 7 16 6 6 2 3 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_032069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005486730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB636265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY437398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ227255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ227256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U88572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000005539   ⟹   ENSRNOP00000005539
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl754,934,250 - 55,592,096 (+)Ensembl
Rnor_6.0 Ensembl764,672,722 - 64,864,227 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000005545   ⟹   ENSRNOP00000005545
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl755,493,231 - 55,592,273 (+)Ensembl
Rnor_6.0 Ensembl764,768,742 - 64,864,404 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000064448   ⟹   ENSRNOP00000059908
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl755,397,072 - 55,581,859 (+)Ensembl
Rnor_6.0 Ensembl764,672,722 - 64,864,155 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000088861   ⟹   ENSRNOP00000073984
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl755,312,410 - 55,582,808 (+)Ensembl
Rnor_6.0 Ensembl764,769,089 - 64,854,248 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000095939   ⟹   ENSRNOP00000086684
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl755,194,360 - 55,582,808 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000103170   ⟹   ENSRNOP00000089072
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl754,935,257 - 55,582,808 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000104327   ⟹   ENSRNOP00000093733
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl755,397,045 - 55,582,808 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000107252   ⟹   ENSRNOP00000091086
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl755,312,227 - 55,582,808 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116059   ⟹   ENSRNOP00000076991
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl754,934,250 - 55,582,808 (+)Ensembl
RefSeq Acc Id: NM_032069   ⟹   NP_114458
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8757,197,852 - 57,468,413 (+)NCBI
mRatBN7.2755,312,227 - 55,582,808 (+)NCBI
Rnor_6.0764,672,723 - 64,854,939 (+)NCBI
Rnor_5.0764,890,319 - 65,072,097 (+)NCBI
RGSC_v3.4759,157,276 - 59,306,131 (+)RGD
Celera752,073,046 - 52,340,208 (+)RGD
Sequence:
RefSeq Acc Id: XM_039079958   ⟹   XP_038935886
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8757,225,885 - 57,477,877 (+)NCBI
mRatBN7.2755,339,602 - 55,592,274 (+)NCBI
RefSeq Acc Id: XM_039079960   ⟹   XP_038935888
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8756,820,501 - 57,469,058 (+)NCBI
mRatBN7.2754,934,856 - 55,583,453 (+)NCBI
RefSeq Acc Id: XM_039079961   ⟹   XP_038935889
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8757,194,132 - 57,469,058 (+)NCBI
mRatBN7.2755,310,970 - 55,583,453 (+)NCBI
RefSeq Acc Id: XM_039079962   ⟹   XP_038935890
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8757,059,719 - 57,469,058 (+)NCBI
mRatBN7.2755,190,642 - 55,583,453 (+)NCBI
RefSeq Acc Id: XM_039079963   ⟹   XP_038935891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8757,194,132 - 57,477,877 (+)NCBI
mRatBN7.2755,310,970 - 55,592,274 (+)NCBI
RefSeq Acc Id: XM_039079964   ⟹   XP_038935892
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8757,225,892 - 57,469,058 (+)NCBI
mRatBN7.2755,339,604 - 55,583,453 (+)NCBI
RefSeq Acc Id: XM_039079965   ⟹   XP_038935893
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8756,820,501 - 57,469,058 (+)NCBI
mRatBN7.2754,934,856 - 55,583,453 (+)NCBI
RefSeq Acc Id: XM_039079966   ⟹   XP_038935894
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8757,194,132 - 57,469,058 (+)NCBI
mRatBN7.2755,310,970 - 55,583,453 (+)NCBI
RefSeq Acc Id: XM_039079967   ⟹   XP_038935895
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8757,375,296 - 57,469,058 (+)NCBI
mRatBN7.2755,489,649 - 55,583,453 (+)NCBI
RefSeq Acc Id: XM_039079968   ⟹   XP_038935896
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8757,375,305 - 57,469,058 (+)NCBI
mRatBN7.2755,489,651 - 55,583,453 (+)NCBI
RefSeq Acc Id: XM_039079969   ⟹   XP_038935897
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8757,375,301 - 57,477,877 (+)NCBI
mRatBN7.2755,489,650 - 55,592,274 (+)NCBI
RefSeq Acc Id: XM_039079970   ⟹   XP_038935898
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8757,385,637 - 57,469,058 (+)NCBI
mRatBN7.2755,500,025 - 55,583,453 (+)NCBI
RefSeq Acc Id: XM_063264313   ⟹   XP_063120383
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8757,225,891 - 57,477,877 (+)NCBI
RefSeq Acc Id: XM_063264314   ⟹   XP_063120384
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8757,059,719 - 57,469,058 (+)NCBI
RefSeq Acc Id: XM_063264315   ⟹   XP_063120385
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8757,059,716 - 57,469,058 (+)NCBI
RefSeq Acc Id: XM_063264316   ⟹   XP_063120386
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8757,059,724 - 57,469,058 (+)NCBI
RefSeq Acc Id: XM_063264317   ⟹   XP_063120387
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8757,059,720 - 57,477,877 (+)NCBI
RefSeq Acc Id: XM_063264318   ⟹   XP_063120388
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8757,194,133 - 57,469,058 (+)NCBI
RefSeq Acc Id: XM_063264319   ⟹   XP_063120389
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8757,194,132 - 57,477,877 (+)NCBI
RefSeq Acc Id: XM_063264320   ⟹   XP_063120390
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8757,059,724 - 57,469,058 (+)NCBI
RefSeq Acc Id: XM_063264321   ⟹   XP_063120391
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8757,194,132 - 57,477,877 (+)NCBI
RefSeq Acc Id: XR_005486730
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8757,225,219 - 57,407,504 (+)NCBI
mRatBN7.2755,339,598 - 55,521,892 (+)NCBI
Protein Sequences
Protein RefSeqs NP_114458 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935886 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935888 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935889 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935890 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935891 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935892 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935893 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935894 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935895 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935896 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935897 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935898 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120383 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120384 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120385 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120386 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120387 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120388 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120389 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120390 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120391 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB51689 (Get FASTA)   NCBI Sequence Viewer  
  AAR08916 (Get FASTA)   NCBI Sequence Viewer  
  ABB46288 (Get FASTA)   NCBI Sequence Viewer  
  ABB46289 (Get FASTA)   NCBI Sequence Viewer  
  BAK38490 (Get FASTA)   NCBI Sequence Viewer  
  EDM16576 (Get FASTA)   NCBI Sequence Viewer  
  EDM16577 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000005539.6
  ENSRNOP00000005545
  ENSRNOP00000005545.3
  ENSRNOP00000059908.4
  ENSRNOP00000073984
  ENSRNOP00000073984.2
  ENSRNOP00000076991
  ENSRNOP00000076991.1
  ENSRNOP00000086684.1
  ENSRNOP00000089072
  ENSRNOP00000089072.1
  ENSRNOP00000091086
  ENSRNOP00000091086.1
  ENSRNOP00000093733.1
GenBank Protein P97879 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_114458   ⟸   NM_032069
- UniProtKB: P97879 (UniProtKB/Swiss-Prot),   A6IGX1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000005539   ⟸   ENSRNOT00000005539
RefSeq Acc Id: ENSRNOP00000005545   ⟸   ENSRNOT00000005545
RefSeq Acc Id: ENSRNOP00000073984   ⟸   ENSRNOT00000088861
RefSeq Acc Id: ENSRNOP00000059908   ⟸   ENSRNOT00000064448
RefSeq Acc Id: XP_038935888   ⟸   XM_039079960
- Peptide Label: isoform X4
- UniProtKB: F1LMX8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935893   ⟸   XM_039079965
- Peptide Label: isoform X10
- UniProtKB: F1LMX8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935890   ⟸   XM_039079962
- Peptide Label: isoform X6
- UniProtKB: A0A8I6GEA5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935891   ⟸   XM_039079963
- Peptide Label: isoform X7
- UniProtKB: Q30A71 (UniProtKB/TrEMBL),   A6IGX1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935889   ⟸   XM_039079961
- Peptide Label: isoform X5
- UniProtKB: A0A8I6AEY6 (UniProtKB/TrEMBL),   A6IGX0 (UniProtKB/TrEMBL),   A6IGX1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935894   ⟸   XM_039079966
- Peptide Label: isoform X11
- UniProtKB: A6IGX1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935886   ⟸   XM_039079958
- Peptide Label: isoform X1
- UniProtKB: F1LMX8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935892   ⟸   XM_039079964
- Peptide Label: isoform X8
- UniProtKB: A0A8I5Y580 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935895   ⟸   XM_039079967
- Peptide Label: isoform X18
- UniProtKB: Q30A72 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935897   ⟸   XM_039079969
- Peptide Label: isoform X20
- UniProtKB: A0A140TA96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935896   ⟸   XM_039079968
- Peptide Label: isoform X19
RefSeq Acc Id: XP_038935898   ⟸   XM_039079970
- Peptide Label: isoform X21
RefSeq Acc Id: ENSRNOP00000076991   ⟸   ENSRNOT00000116059
RefSeq Acc Id: ENSRNOP00000086684   ⟸   ENSRNOT00000095939
RefSeq Acc Id: ENSRNOP00000091086   ⟸   ENSRNOT00000107252
RefSeq Acc Id: ENSRNOP00000089072   ⟸   ENSRNOT00000103170
RefSeq Acc Id: ENSRNOP00000093733   ⟸   ENSRNOT00000104327
RefSeq Acc Id: XP_063120385   ⟸   XM_063264315
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063120384   ⟸   XM_063264314
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063120387   ⟸   XM_063264317
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063120386   ⟸   XM_063264316
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063120390   ⟸   XM_063264320
- Peptide Label: isoform X16
RefSeq Acc Id: XP_063120389   ⟸   XM_063264319
- Peptide Label: isoform X15
RefSeq Acc Id: XP_063120391   ⟸   XM_063264321
- Peptide Label: isoform X17
RefSeq Acc Id: XP_063120388   ⟸   XM_063264318
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063120383   ⟸   XM_063264313
- Peptide Label: isoform X2
Protein Domains
PDZ

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97879-F1-model_v2 AlphaFold P97879 1-1112 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695237
Promoter ID:EPDNEW_R5756
Type:initiation region
Name:Grip1_1
Description:glutamate receptor interacting protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0764,768,995 - 64,769,055EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621667 AgrOrtholog
BioCyc Gene G2FUF-33920 BioCyc
Ensembl Genes ENSRNOG00000004013 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005539.8 UniProtKB/TrEMBL
  ENSRNOT00000005545.6 UniProtKB/TrEMBL
  ENSRNOT00000064448.5 UniProtKB/TrEMBL
  ENSRNOT00000088861 ENTREZGENE
  ENSRNOT00000088861.2 UniProtKB/TrEMBL
  ENSRNOT00000095939.1 UniProtKB/TrEMBL
  ENSRNOT00000103170.1 UniProtKB/TrEMBL
  ENSRNOT00000104327.1 UniProtKB/TrEMBL
  ENSRNOT00000107252.1 UniProtKB/TrEMBL
  ENSRNOT00000116059.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GRIP1/2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:84016 UniProtKB/Swiss-Prot
NCBI Gene 84016 ENTREZGENE
PANTHER PTHR46227 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR46227:SF3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Grip1 PhenoGen
PROSITE PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004013 RatGTEx
SMART PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50156 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K6Y0_RAT UniProtKB/TrEMBL
  A0A140TA96 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y580 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AEY6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AK56_RAT UniProtKB/TrEMBL
  A0A8I6GEA5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GGW0_RAT UniProtKB/TrEMBL
  A6IGX0 ENTREZGENE, UniProtKB/TrEMBL
  A6IGX1 ENTREZGENE, UniProtKB/TrEMBL
  F1LMX8 ENTREZGENE, UniProtKB/TrEMBL
  F1LRA4_RAT UniProtKB/TrEMBL
  F5HTD6_RAT UniProtKB/TrEMBL
  GRIP1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q30A71 ENTREZGENE, UniProtKB/TrEMBL
  Q30A72 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Grip1  glutamate receptor interacting protein 1    Glutamate receptor interacting protein  Name updated 1299863 APPROVED
2002-08-07 Grip1  Glutamate receptor interacting protein      Symbol and Name status set to provisional 70820 PROVISIONAL