Gene: Pi4kb (phosphatidylinositol 4-kinase, catalytic, beta)
Rattus norvegicus
Symbol:
Pi4kb
Name:
phosphatidylinositol 4-kinase, catalytic, beta
Description:
ENCODES a protein that exhibits 1-phosphatidylinositol 4-kinase activity; INVOLVED IN phosphatidylinositol biosynthetic process (inferred); phosphatidylinositol-mediated signaling (inferred); signal transduction (inferred); PARTICIPATES IN inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; FOUND IN cytoplasm; cytosol; plasma membrane; INTERACTS WITH 17beta-estradiol; 2,4-dinitrotoluene; ammonium chloride
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
catalytic phosphatidylinositol 4-kinase beta; phosphatidylinositol 4-kinase beta; phosphatidylinositol 4-kinase, catalytic, beta polypeptide; PI4K-beta; PI4Kbeta; Pik4cb; pik4cb; ptdIns 4-kinase beta
Orthologs:
Homo sapiens : PI4KB
(phosphatidylinositol 4-kinase, catalytic, beta)
HGNC
Pi4kb
(phosphatidylinositol 4-kinase, catalytic, beta polypeptide)
MGI
Latest Assembly:
RGSC Genome Assembly v3.4
Position:
Map Chr Position Strand Source Rat Cytogenetic Map 2 q34 NCBI RGSC Genome Assembly v5.0 2 215,634,441 - 215,666,468 + NCBI RGSC Genome Assembly v3.4 2 189,874,613 - 189,906,640 + NCBI Rat Celera Assembly 2 175,082,416 - 175,114,456 + NCBI Genome Assembly 3.1 2 189,834,020 - 189,866,048 + NCBI
Model
Gene Ontology Annotations
Biological Process phosphatidylinositol biosynthetic process IEA InterPro:IPR027003 1600115 GO_REF:0000002 InterPro GO_REF:0000002 phosphatidylinositol-mediated signaling IEA InterPro:IPR015433 1600115 GO_REF:0000002 InterPro GO_REF:0000002 signal transduction TAS 625563 RGD
631501 Bp101 Blood pressure QTL 101 2.4 Blood pressure systolic 2 155920808 210636008 Rat 1358900 Bw48 Body weight QTL 48 4.88 Body weight 2 163154358 227150051 Rat 61469 Bp16 Blood pressure QTL 16 5.64 Blood pressure 2 177484675 222484675 Rat 71113 Cari2 Carrageenan-induced inflammation QTL 2 2.7 .009 Carrageenan-induced inflammation 2 146659370 210636169 Rat 631507 Bp105 Blood pressure QTL 105 .001 Blood pressure 2 116874922 221284686 Rat 70162 Bp63 Blood pressure QTL 63 5.64 Blood pressure 2 177484675 222484675 Rat 70175 BpQTLCluster3 Blood pressure QTL cluster 3 2.76 Blood pressure 2 140403692 210636008 Rat 631522 Bp74 Blood pressure QTL 74 .05 Blood pressure systolic 2 179302449 191378271 Rat 61374 Edpm2 Estrogen-dependent pituitary mass QTL 2 4.42 .86 Gland mass pituitary 2 77630629 210636169 Rat 61417 Cia10 Collagen induced arthritis QTL 10 3.4 Joint/bone inflammation type II collagen induced 2 188136088 233136088 Rat 724568 Uae13 Urinary albumin excretion QTL 13 4.4 Renal function urine albumin level 2 161170272 218568266 Rat 1354648 Bp239 Blood pressure QTL 239 .001 Blood pressure systolic 2 66680209 235799396 Rat 634308 Sach6 Saccharin preference QTL 6 4.9 Consumption level saccharin preference 2 116874922 221284686 Rat 724534 Uae6 Urinary albumin excretion QTL 6 10 Renal function urine albumin level 2 79796833 227150249 Rat 1298074 Bp164 Blood pressure QTL 164 .003 Blood pressure salt-loaded systolic 2 165636169 210636169 Rat 1298076 Bp166 Blood pressure QTL 166 .0009 Blood pressure systolic 2 165636169 210636169 Rat 1298080 Bp163 Blood pressure QTL 163 .02 Blood pressure systolic 2 66680022 210636169 Rat 1298085 Bp165 Blood pressure QTL 165 .0006 Blood pressure salt-loaded systolic 2 165636169 210636169 Rat 1331760 Bp206 Blood pressure QTL 206 3.62454 Blood pressure time series calculation 2 56214854 210636169 Rat 631266 Bp132 Blood pressure QTL 132 .0005 Blood pressure systolic 2 46542246 210636169 Rat 61401 Niddm2 Non-insulin dependent diabetes mellitus QTL 2 4.54 Glucose level postprandial 2 152256313 197256313 Rat 1354622 Kidm16 Kidney mass QTL 16 3 Kidney mass left kidney mass 2 82826122 231465091 Rat 1300165 Rf9 Renal function QTL 9 3.28 Renal function hypertension related glomerular damage 2 138700979 210636169 Rat 1331805 Cm29 Cardiac mass QTL 29 3.50746 Cardiac mass 2 146228221 232307864 Rat 1331794 Bp202 Blood pressure QTL 202 3.66819 Blood pressure systolic 2 146228221 232307864 Rat 1331734 Bp204 Blood pressure QTL 204 3.61192 Blood pressure mean arterial 2 174730375 232307864 Rat 1354601 Slep1 Serum leptin concentration QTL 1 5.39 Hormone level leptin 2 42882523 191378271 Rat 1354605 Rf48 Renal function QTL 48 2.9 Creatinine level serum 2 75806326 214989298 Rat 1354609 Niddm62 Non-insulin dependent diabetes mellitus QTL 62 4.72 .000006 Insulin level post-pancreatectomy 2 156142685 210636169 Rat 1358917 Cm42 Cardiac mass QTL 42 2.82 Cardiac mass 2 24474447 212169089 Rat 1354649 Kidm17 Kidney mass QTL 17 2.9 Kidney mass left kidney mass adjujsted for tibia length 2 82826122 236153712 Rat 1359022 Ppulsi1 Prepulse inhibition QTL 1 3.63 Prepulse inhibition 2 141755026 222281918 Rat 1359031 Bp275 Blood pressure QTL 275 Blood pressure systolic 2 183664122 228664122 Rat 1359032 Hrtrt18 Heart rate QTL 18 Heart rate salt-induced bradycardia 2 163154227 200390471 Rat 1549833 Bp257 Blood pressure QTL 257 .003 Blood pressure mean arterial 2 174727312 192363025 Rat 1358913 Cm41 Cardiac mass QTL 41 2.73 Cardiac mass 2 24474447 212169089 Rat 1554319 Bmd2 Bone mineral density QTL 2 13.4 .0001 Bone mineral density spine area by pQCT 2 118264840 221131552 Rat 1581576 Pur7 Proteinuria QTL 7 .0001 Renal function urine protein level 2 79796977 227150051 Rat 1581569 Uae32 Urinary albumin excretion QTL 32 .0001 Renal function urine albumin level 2 79796977 227150051 Rat 1581578 Cm49 Cardiac mass QTL 49 4.9 .01 Cardiac mass left ventricle 2 148790600 227150249 Rat 1578648 Bss11 Bone structure and strength QTL 11 4.7 Bone structure femoral neck cortical area 2 118264490 220244597 Rat 1578671 Bmd10 Bone mineral density QTL 10 5.4 Bone mineral density femoral neck cortical vBMD 2 9670332 227150249 Rat 1598805 Memor8 Memory QTL 8 3 Memory navigation-spatial 2 155920709 197555821 Rat 1598833 Bp295 Blood pressure QTL 295 3.5 Blood pressure systolic 2 154238265 199238265 Rat 1358356 Srcrt1 Stress Responsive Cort QTL1 3.66 Hypothalamic-pituitary-adrenal axis corticosterone post-stress 2 167857161 231465091 Rat 1581502 Esta3 Estrogen-induced thymic atrophy QTL 3 Gland mass thymus 2 141755026 197256313 Rat 1641891 Alcrsp17 Alcohol response QTL 17 Alcohol response loss of righting reflex 2 155101972 247295816 Rat 1641925 Alcrsp2 Alcohol response QTL 2 Alcohol response loss of righting reflex 2 155101972 230157845 Rat 2293084 Iddm26 Insulin dependent diabetes mellitus QTL 26 2.9 Glucose level insulin-dependent 2 181710214 222281918 Rat 2300189 Bmd48 Bone mineral density QTL 48 5.8 .0001 Bone mineral density 2 187512114 232512114 Rat 2301966 Bp322 Blood pressure QTL 322 3.58 Blood pressure systolic 2 156142685 210636169 Rat 2306901 Bp337 Blood pressure QTL 337 .01 Blood pressure salt-loaded systolic 2 170338294 236153712 Rat 61467 Bp14 Blood pressure QTL 14 2.2 Blood pressure 2 42866342 210636008 Rat 1302793 Bw16 Body weight QTL 16 5 .0001 Body weight 2 163154358 210636008 Rat 6903312 Bw112 Body weight QTL 112 3.2 .0013 Body weight 2 148790758 191378142 Rat
Gene Ontology Annotations
