Gene: Wnk1 (WNK lysine deficient protein kinase 1)  Rattus norvegicus

Symbol: Wnk1
Name: WNK lysine deficient protein kinase 1
Description: ENCODES a protein that exhibits ATP binding; magnesium ion binding; potassium channel inhibitor activity; INVOLVED IN intracellular protein kinase cascade; negative regulation of kinase activity; negative regulation of protein serine/threonine kinase activity; PARTICIPATES IN Erk5 MAPK signaling pathway; ASSOCIATED WITH Hypertension (ortholog); Neuropathy, Hereditary Sensory And Autonomic, Type IIA (ortholog); Pseudohypoaldosteronism (ortholog); FOUND IN cytoplasm; INTERACTS WITH 17alpha-ethynylestradiol; 2,4,6-trinitrotoluene; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: hereditary sensory neuropathy, type II; Hsn2; Prkwnk1; prkwnk1; protein kinase lysine-deficient 1; protein kinase with no lysine 1; protein kinase, lysine deficient 1; protein kinase, lysine-deficient 1; serine/threonine-protein kinase WNK1; WNK lysine deficient protein kinase 1
Orthologs: Homo sapiens : WNK1 (WNK lysine deficient protein kinase 1)  HGNC
Mus musculus : Wnk1 (WNK lysine deficient protein kinase 1)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map4q42 NCBI
RGSC Genome Assembly v5.04219,537,467 - 219,662,981-NCBI
RGSC Genome Assembly v3.44156,297,841 - 156,421,820-NCBI
Rat Celera Assembly4141,980,237 - 142,105,859-NCBI
Genome Assembly 3.14156,542,681 - 156,666,661-NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Wnk1
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Ensembl Gene
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RGD Object Information
RGD ID: 621141
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE