Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | ISO | Pja2 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of PJA2 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of PJA2 mRNA | CTD | PMID:15576828 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of PJA2 mRNA | CTD | PMID:32145629 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Pja2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PJA2 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PJA2 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Pja2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PJA2 mRNA | CTD | PMID:15034205 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Pja2 (Mus musculus) | 6480464 | AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PJA2 mRNA] | CTD | PMID:15034205 | 2-hydroxypropanoic acid | increases expression | ISO | PJA2 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of PJA2 mRNA | CTD | PMID:30851411 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Pja2 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of PJA2 mRNA | CTD | PMID:26251327 | 4-hydroxyphenyl retinamide | decreases expression | ISO | Pja2 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of PJA2 mRNA | CTD | PMID:28973697 | acrolein | multiple interactions | ISO | PJA2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in increased oxidation of PJA2 mRNA | CTD | PMID:32845096 | aflatoxin B1 | decreases methylation | ISO | PJA2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of PJA2 gene and Aflatoxin B1 results in decreased methylation of PJA2 intron | CTD | PMID:27153756 and PMID:30157460 | Aflatoxin B2 alpha | decreases methylation | ISO | PJA2 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of PJA2 intron | CTD | PMID:30157460 | aflatoxin M1 | decreases expression | ISO | PJA2 (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of PJA2 mRNA | CTD | PMID:30928695 | all-trans-retinoic acid | increases expression | ISO | PJA2 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of PJA2 mRNA | CTD | PMID:23724009 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of PJA2 mRNA | CTD | PMID:16483693 | aristolochic acid A | decreases expression | ISO | PJA2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of PJA2 mRNA | CTD | PMID:33212167 | Aroclor 1254 | decreases expression | ISO | Pja2 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of PJA2 mRNA | CTD | PMID:23650126 | arsenite(3-) | multiple interactions | ISO | PJA2 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to PJA2 mRNA] | CTD | PMID:32406909 | benzo[a]pyrene | multiple interactions | ISO | Pja2 (Mus musculus) | 6480464 | AHR protein inhibits the reaction [Benzo(a)pyrene results in increased expression of PJA2 mRNA] | CTD | PMID:15034205 | benzo[a]pyrene | increases expression | ISO | Pja2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of PJA2 mRNA | CTD | PMID:15034205 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | PJA2 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20018196 | bis(2-ethylhexyl) phthalate | increases expression | ISO | Pja2 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of PJA2 mRNA | CTD | PMID:21318169 | bis(2-ethylhexyl) phthalate | increases expression | EXP | | 6480464 | Diethylhexyl Phthalate results in increased expression of PJA2 mRNA | CTD | PMID:21318169 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of PJA2 mRNA | CTD | PMID:25181051 and PMID:32145629 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of PJA2 gene | CTD | PMID:28505145 | cadmium atom | multiple interactions | ISO | PJA2 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PJA2 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | PJA2 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PJA2 mRNA | CTD | PMID:35301059 | caffeine | decreases phosphorylation | ISO | PJA2 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of PJA2 protein | CTD | PMID:35688186 | chloropicrin | increases expression | ISO | PJA2 (Homo sapiens) | 6480464 | chloropicrin results in increased expression of PJA2 mRNA | CTD | PMID:26352163 | chloroprene | increases expression | EXP | | 6480464 | Chloroprene results in increased expression of PJA2 mRNA | CTD | PMID:23125180 | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of PJA2 mRNA | CTD | PMID:18668222 | cocaine | decreases expression | EXP | | 6480464 | Cocaine results in decreased expression of PJA2 mRNA | CTD | PMID:16076954 | cyclosporin A | increases expression | ISO | PJA2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of PJA2 mRNA | CTD | PMID:20106945 and PMID:25562108 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of PJA2 mRNA | CTD | PMID:21266533 | dicrotophos | decreases expression | ISO | PJA2 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of PJA2 mRNA | CTD | PMID:28302478 | ethanol | affects splicing | ISO | Pja2 (Mus musculus) | 6480464 | Ethanol affects the splicing of PJA2 mRNA | CTD | PMID:30319688 | fenofibrate | increases expression | ISO | Pja2 (Mus musculus) | 6480464 | Fenofibrate results in increased expression of PJA2 mRNA | CTD | PMID:21318169 | fenofibrate | multiple interactions | ISO | Pja2 (Mus musculus) | 6480464 | PPARA protein affects the reaction [Fenofibrate results in increased expression of PJA2 mRNA] | CTD | PMID:21318169 | fenthion | increases expression | ISO | Pja2 (Mus musculus) | 6480464 | Fenthion results in increased expression of PJA2 mRNA | CTD | PMID:34813904 | ferroheme b | decreases expression | ISO | Pja2 (Mus musculus) | 6480464 | Heme metabolite results in decreased expression of PJA2 mRNA | CTD | PMID:19191707 | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of PJA2 mRNA | CTD | PMID:24136188 | folic acid | decreases expression | ISO | Pja2 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of PJA2 mRNA | CTD | PMID:25629700 | FR900359 | decreases phosphorylation | ISO | PJA2 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of PJA2 protein | CTD | PMID:37730182 | gamma-hexachlorocyclohexane | increases expression | EXP | | 6480464 | Hexachlorocyclohexane results in increased expression of PJA2 mRNA | CTD | PMID:17785943 | gemcitabine | increases expression | ISO | PJA2 (Homo sapiens) | 6480464 | Gemcitabine results in increased expression of PJA2 mRNA | CTD | PMID:17039268 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of PJA2 mRNA | CTD | PMID:33387578 | heme b | decreases expression | ISO | Pja2 (Mus musculus) | 6480464 | Heme metabolite results in decreased expression of PJA2 mRNA | CTD | PMID:19191707 | hydrogen peroxide | affects expression | ISO | PJA2 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of PJA2 mRNA | CTD | PMID:20044591 | indometacin | decreases expression | ISO | PJA2 (Homo sapiens) | 6480464 | Indomethacin results in decreased expression of PJA2 mRNA | CTD | PMID:16984733 | leflunomide | increases expression | ISO | PJA2 (Homo sapiens) | 6480464 | leflunomide results in increased expression of PJA2 mRNA | CTD | PMID:28988120 | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of PJA2 mRNA | CTD | PMID:30467583 | methidathion | increases expression | ISO | Pja2 (Mus musculus) | 6480464 | methidathion results in increased expression of PJA2 mRNA | CTD | PMID:34813904 | methylseleninic acid | increases expression | ISO | PJA2 (Homo sapiens) | 6480464 | methylselenic acid results in increased expression of PJA2 mRNA | CTD | PMID:18548127 | ozone | multiple interactions | ISO | PJA2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in increased oxidation of PJA2 mRNA | CTD | PMID:32845096 | paracetamol | affects expression | ISO | Pja2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of PJA2 mRNA | CTD | PMID:17562736 | phenobarbital | affects expression | ISO | Pja2 (Mus musculus) | 6480464 | Phenobarbital affects the expression of PJA2 mRNA | CTD | PMID:23091169 | quercetin | increases expression | EXP | | 6480464 | Quercetin results in increased expression of PJA2 mRNA | CTD | PMID:17103110 | rac-lactic acid | increases expression | ISO | PJA2 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of PJA2 mRNA | CTD | PMID:30851411 | resveratrol | multiple interactions | ISO | PJA2 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of PJA2 mRNA | CTD | PMID:23557933 | silver atom | decreases expression | ISO | Pja2 (Mus musculus) | 6480464 | Silver results in decreased expression of PJA2 mRNA | CTD | PMID:27131904 | silver(0) | decreases expression | ISO | Pja2 (Mus musculus) | 6480464 | Silver results in decreased expression of PJA2 mRNA | CTD | PMID:27131904 | sodium arsenite | decreases expression | ISO | PJA2 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of PJA2 mRNA | CTD | PMID:28595984 | sodium arsenite | increases expression | ISO | Pja2 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of PJA2 mRNA | CTD | PMID:36209798 | sodium arsenite | affects expression | ISO | PJA2 (Homo sapiens) | 6480464 | sodium arsenite affects the expression of PJA2 mRNA | CTD | PMID:34032870 | succimer | multiple interactions | ISO | Pja2 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of PJA2 mRNA and [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of PJA2 mRNA | CTD | PMID:21641980 and PMID:26378955 | tunicamycin | increases expression | ISO | PJA2 (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of PJA2 mRNA | CTD | PMID:22378314 and PMID:29453283 | urethane | increases expression | ISO | PJA2 (Homo sapiens) | 6480464 | Urethane results in increased expression of PJA2 mRNA | CTD | PMID:28818685 | valproic acid | decreases expression | ISO | PJA2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of PJA2 mRNA | CTD | PMID:23179753 | |