Suox (sulfite oxidase) - Rat Genome Database

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Gene: Suox (sulfite oxidase) Rattus norvegicus
Analyze
Symbol: Suox
Name: sulfite oxidase
RGD ID: 619994
Description: Enables heme binding activity; molybdopterin cofactor binding activity; and sulfite oxidase activity. Involved in response to nutrient. Predicted to be located in mitochondrial intermembrane space. Predicted to be active in mitochondrion. Biomarker of steatotic liver disease. Human ortholog(s) of this gene implicated in inherited metabolic disorder and isolated sulfite oxidase deficiency. Orthologous to human SUOX (sulfite oxidase); PARTICIPATES IN sulfite oxidase deficiency pathway; sulfur metabolic pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: sulfite oxidase, mitochondrial
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr871,687,666 - 1,691,759 (-)NCBIGRCr8
mRatBN7.271,103,149 - 1,107,156 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl71,103,151 - 1,107,038 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx73,866,328 - 3,868,898 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.075,742,000 - 5,744,570 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.076,039,038 - 6,041,607 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.073,098,228 - 3,102,179 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl73,098,245 - 3,102,142 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.073,070,928 - 3,074,829 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,973,471 - 1,976,040 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.171,973,472 - 1,976,040 (-)NCBI
Celera7973,358 - 975,927 (-)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4-hydroxyphenyl retinamide  (ISO)
4-octylphenol  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
avobenzone  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium dichloride  (EXP)
cannabidiol  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cisplatin  (EXP)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dextran sulfate  (ISO)
diazinon  (ISO)
Diisodecyl phthalate  (ISO)
dioscin  (ISO)
epoxiconazole  (ISO)
fipronil  (EXP)
fluoranthene  (ISO)
flutamide  (EXP)
folic acid  (ISO)
furan  (EXP)
gentamycin  (EXP)
glafenine  (EXP)
hydrogen peroxide  (ISO)
iron dichloride  (ISO)
ivermectin  (ISO)
ketamine  (EXP)
lipopolysaccharide  (ISO)
menadione  (ISO)
mercury dichloride  (EXP)
methapyrilene  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosomorpholine  (EXP)
nefazodone  (EXP)
nimesulide  (EXP)
nitrofen  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorododecanoic acid  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP)
sunitinib  (ISO)
T-2 toxin  (EXP)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
tunicamycin  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vancomycin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Effect of dietary protein and methionine on sulfite oxidase activity in rats. Amy NK J Nutr. 1988 Aug;118(8):941-4.
2. Molecular cloning of rat liver sulfite oxidase. Expression of a eukaryotic Mo-pterin-containing enzyme in Escherichia coli. Garrett RM and Rajagopalan KV, J Biol Chem 1994 Jan 7;269(1):272-6.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Isolated sulfite oxidase deficiency: identification of 12 novel SUOX mutations in 10 patients. Johnson JL, etal., Hum Mutat. 2002 Jul;20(1):74.
6. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
7. A proteomic investigation of drug-induced steatosis in rat liver. Meneses-Lorente G, etal., Chem Res Toxicol. 2004 May;17(5):605-12.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. Evidence for participation of the inner membrane in the import of sulfite oxidase into the intermembrane space of liver mitochondria. Ono H and Ito A, Biochem Biophys Res Commun. 1982 Jul 16;107(1):258-64.
12. Biosynthesis of sulfite oxidase in rat liver - presence of a large precursor form of the enzyme in cytosol. Ono H and Ito A, J Biochem (Tokyo). 1982 Jan;91(1):117-23.
13. Transport of the precursor for sulfite oxidase into intermembrane space of liver mitochondria: characterization of import and processing activities. Ono H and Ito A, J Biochem (Tokyo). 1984 Feb;95(2):345-52.
14. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
15. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
16. GOA pipeline RGD automated data pipeline
17. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
18. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
19. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
20. Sulphite oxidase gene expression in human brain and in other human and rat tissues. Woo WH, etal., Biochem Biophys Res Commun 2003 Jun 6;305(3):619-23.
Additional References at PubMed
PMID:2249998   PMID:3393528   PMID:14651853   PMID:17613108   PMID:18614015  


Genomics

Comparative Map Data
Suox
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr871,687,666 - 1,691,759 (-)NCBIGRCr8
mRatBN7.271,103,149 - 1,107,156 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl71,103,151 - 1,107,038 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx73,866,328 - 3,868,898 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.075,742,000 - 5,744,570 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.076,039,038 - 6,041,607 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.073,098,228 - 3,102,179 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl73,098,245 - 3,102,142 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.073,070,928 - 3,074,829 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,973,471 - 1,976,040 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.171,973,472 - 1,976,040 (-)NCBI
Celera7973,358 - 975,927 (-)NCBICelera
Cytogenetic Map7q11NCBI
SUOX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381255,997,276 - 56,005,525 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1255,997,180 - 56,006,641 (+)EnsemblGRCh38hg38GRCh38
GRCh371256,391,060 - 56,399,309 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361254,677,310 - 54,685,576 (+)NCBINCBI36Build 36hg18NCBI36
Build 341254,681,548 - 54,685,109NCBI
Celera1256,043,727 - 56,051,993 (+)NCBICelera
Cytogenetic Map12q13.2NCBI
HuRef1253,429,929 - 53,438,195 (+)NCBIHuRef
CHM1_11256,358,154 - 56,366,418 (+)NCBICHM1_1
T2T-CHM13v2.01255,964,339 - 55,972,588 (+)NCBIT2T-CHM13v2.0
Suox
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910128,505,756 - 128,509,787 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10128,505,763 - 128,509,942 (-)EnsemblGRCm39 Ensembl
GRCm3810128,669,887 - 128,673,918 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,669,894 - 128,674,073 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710128,106,943 - 128,110,974 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610128,072,843 - 128,076,810 (-)NCBIMGSCv36mm8
Celera10131,061,992 - 131,066,023 (-)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1077.12NCBI
Suox
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554583,585,482 - 3,590,559 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554583,584,390 - 3,589,764 (+)NCBIChiLan1.0ChiLan1.0
SUOX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21038,324,140 - 38,332,458 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11238,320,911 - 38,329,282 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01232,907,456 - 32,915,788 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11233,157,277 - 33,165,712 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1233,157,277 - 33,165,661 (-)Ensemblpanpan1.1panPan2
SUOX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.110327,656 - 331,826 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl10327,671 - 331,825 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha10389,623 - 393,749 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.010334,299 - 338,424 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl10334,270 - 338,424 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.110312,312 - 316,438 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.010554,865 - 558,990 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.010679,365 - 683,493 (+)NCBIUU_Cfam_GSD_1.0
Suox
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494558,454,620 - 58,458,747 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936646411,084 - 415,732 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936646411,543 - 415,709 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SUOX
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl521,395,262 - 21,399,710 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1521,395,246 - 21,399,715 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SUOX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11151,935,809 - 51,943,090 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1151,939,809 - 51,942,603 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037194,044,119 - 194,051,273 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Suox
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480212,047,270 - 12,054,523 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480212,049,787 - 12,054,810 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Suox
14 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:336
Count of miRNA genes:191
Interacting mature miRNAs:216
Transcripts:ENSRNOT00000008018
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat

Markers in Region
Suox  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.271,103,933 - 1,104,884 (+)MAPPERmRatBN7.2
Rnor_6.073,099,013 - 3,099,963NCBIRnor6.0
Rnor_5.073,071,713 - 3,072,663UniSTSRnor5.0
RGSC_v3.471,974,256 - 1,975,206UniSTSRGSC3.4
Celera7974,143 - 975,093UniSTS
Cytogenetic Map7q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 35 42 35 1 35 2 64 33 25 11
Low 1 8 15 6 18 6 8 9 10 2 16 8
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000008018   ⟹   ENSRNOP00000008018
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl71,103,152 - 1,107,038 (-)Ensembl
Rnor_6.0 Ensembl73,098,245 - 3,102,142 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000108072   ⟹   ENSRNOP00000089321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl71,103,151 - 1,105,518 (-)Ensembl
RefSeq Acc Id: NM_031127   ⟹   NP_112389
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,687,666 - 1,690,235 (-)NCBI
mRatBN7.271,103,149 - 1,105,718 (-)NCBI
Rnor_6.073,098,228 - 3,100,797 (-)NCBI
Rnor_5.073,070,928 - 3,074,829 (-)NCBI
RGSC_v3.471,973,471 - 1,976,040 (-)RGD
Celera7973,358 - 975,927 (-)RGD
Sequence:
RefSeq Acc Id: XM_006240802   ⟹   XP_006240864
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,687,666 - 1,691,759 (-)NCBI
mRatBN7.271,103,149 - 1,107,156 (-)NCBI
Rnor_6.073,098,228 - 3,102,179 (-)NCBI
Rnor_5.073,070,928 - 3,074,829 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240803   ⟹   XP_006240865
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,687,666 - 1,691,561 (-)NCBI
mRatBN7.271,103,149 - 1,105,917 (-)NCBI
Rnor_6.073,098,228 - 3,102,156 (-)NCBI
Rnor_5.073,070,928 - 3,074,829 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063264300   ⟹   XP_063120370
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,687,666 - 1,691,519 (-)NCBI
RefSeq Acc Id: XM_063264301   ⟹   XP_063120371
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,687,666 - 1,691,519 (-)NCBI
RefSeq Acc Id: NP_112389   ⟸   NM_031127
- Peptide Label: precursor
- UniProtKB: Q6P6W0 (UniProtKB/Swiss-Prot),   Q07116 (UniProtKB/Swiss-Prot),   G3V6R5 (UniProtKB/TrEMBL),   A6KSG5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240864   ⟸   XM_006240802
- Peptide Label: isoform X1
- UniProtKB: Q6P6W0 (UniProtKB/Swiss-Prot),   Q07116 (UniProtKB/Swiss-Prot),   G3V6R5 (UniProtKB/TrEMBL),   A6KSG5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240865   ⟸   XM_006240803
- Peptide Label: isoform X1
- UniProtKB: Q6P6W0 (UniProtKB/Swiss-Prot),   Q07116 (UniProtKB/Swiss-Prot),   G3V6R5 (UniProtKB/TrEMBL),   A6KSG5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000008018   ⟸   ENSRNOT00000008018
RefSeq Acc Id: ENSRNOP00000089321   ⟸   ENSRNOT00000108072
RefSeq Acc Id: XP_063120371   ⟸   XM_063264301
- Peptide Label: isoform X1
- UniProtKB: A6KSG5 (UniProtKB/TrEMBL),   G3V6R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120370   ⟸   XM_063264300
- Peptide Label: isoform X1
- UniProtKB: A6KSG5 (UniProtKB/TrEMBL),   G3V6R5 (UniProtKB/TrEMBL)
Protein Domains
Cytochrome b5 heme-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q07116-F1-model_v2 AlphaFold Q07116 1-546 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694946
Promoter ID:EPDNEW_R5471
Type:multiple initiation site
Name:Suox_1
Description:sulfite oxidase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.073,102,103 - 3,102,163EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619994 AgrOrtholog
BioCyc Gene G2FUF-35341 BioCyc
BioCyc Pathway PWY-5326 [sulfite oxidation IV (sulfite oxidase)] BioCyc
  PWY-7927 [sulfide oxidation IV (mitochondria)] BioCyc
BioCyc Pathway Image PWY-5326 BioCyc
  PWY-7927 BioCyc
Ensembl Genes ENSRNOG00000005987 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00065012947 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000008018.6 UniProtKB/TrEMBL
  ENSRNOT00000108072.1 UniProtKB/TrEMBL
  ENSRNOT00065021187 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.650 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.10.120.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.420.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5599452 IMAGE-MGC_LOAD
InterPro Cyt_B5-like_heme/steroid-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_B5-like_heme/steroid_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_B5_heme-BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_E-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MoCF_OxRdtse_dimer UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Mopterin_OxRdtase_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OxRdtase_Mopterin-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OxRdtase_Mopterin-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OxRdtase_Mopterin_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:81805 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72410 IMAGE-MGC_LOAD
NCBI Gene 81805 ENTREZGENE
PANTHER SULFITE OXIDASE, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SULFITE REDUCTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Cyt-b5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Mo-co_dimer UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Oxidored_molyb UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Suox PhenoGen
PRINTS CYTOCHROMEB5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EUMOPTERIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CYTOCHROME_B5_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CYTOCHROME_B5_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MOLYBDOPTERIN_EUK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005987 RatGTEx
  ENSRNOG00065012947 RatGTEx
SMART Cyt-b5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF55856 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56524 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF81296 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6ABF6_RAT UniProtKB/TrEMBL
  A6KSG5 ENTREZGENE, UniProtKB/TrEMBL
  G3V6R5 ENTREZGENE, UniProtKB/TrEMBL
  Q07116 ENTREZGENE
  Q6P6W0 ENTREZGENE
  SUOX_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q6P6W0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-26 Suox  sulfite oxidase      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Suox  sulfite oxidase      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization may be localized to the mitochondrion 634113