Pcyt2 (phosphate cytidylyltransferase 2, ethanolamine) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Pcyt2 (phosphate cytidylyltransferase 2, ethanolamine) Rattus norvegicus
Analyze
Symbol: Pcyt2
Name: phosphate cytidylyltransferase 2, ethanolamine
RGD ID: 619970
Description: Enables ethanolamine-phosphate cytidylyltransferase activity. Predicted to be involved in phosphatidylethanolamine biosynthetic process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 82. Orthologous to human PCYT2 (phosphate cytidylyltransferase 2, ethanolamine); PARTICIPATES IN lamivudine pharmacokinetics pathway; glycerophospholipid metabolic pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CTP:phopshoethanolamine cytidylyltransferase; CTP:phosphoethanolamine cytidylyltransferase; ET; ethanolamine-phosphate cytidylyltransferase; MGC93299; phosphorylethanolamine transferase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810106,387,150 - 106,394,500 (-)NCBIGRCr8
mRatBN7.210105,888,769 - 105,896,182 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10105,888,775 - 105,896,172 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10110,992,673 - 110,999,983 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010110,455,701 - 110,463,011 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010105,809,284 - 105,816,596 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010109,788,348 - 109,795,743 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10109,788,350 - 109,795,697 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010109,381,397 - 109,388,794 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410110,002,023 - 110,009,335 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110110,016,526 - 110,023,839 (-)NCBI
Celera10104,432,228 - 104,439,540 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2,4-trimethylbenzene  (EXP)
1,2-dichloroethane  (ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
aluminium atom  (ISO)
aluminium(0)  (ISO)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
cisplatin  (ISO)
clofibrate  (EXP,ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (EXP)
ethyl methanesulfonate  (ISO)
fenthion  (ISO)
flavonoids  (EXP)
fluoxetine  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
hydrogen sulfide  (ISO)
methamphetamine  (ISO)
methidathion  (ISO)
methyl methanesulfonate  (ISO)
microcystin-LR  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel sulfate  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
pirinixic acid  (EXP,ISO)
potassium dichromate  (ISO)
rotenone  (ISO)
sodium arsenite  (EXP,ISO)
tetrachloromethane  (EXP)
tetraphene  (ISO)
thioacetamide  (EXP)
trichloroethene  (EXP)
triclosan  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Cloning and expression of CTP:phosphoethanolamine cytidylyltransferase cDNA from rat liver. Bladergroen BA, etal., Biochem J 1999 Oct 1;343 Pt 1:107-14.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:14759225   PMID:15489334  


Genomics

Comparative Map Data
Pcyt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810106,387,150 - 106,394,500 (-)NCBIGRCr8
mRatBN7.210105,888,769 - 105,896,182 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10105,888,775 - 105,896,172 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10110,992,673 - 110,999,983 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010110,455,701 - 110,463,011 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010105,809,284 - 105,816,596 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010109,788,348 - 109,795,743 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10109,788,350 - 109,795,697 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010109,381,397 - 109,388,794 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410110,002,023 - 110,009,335 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110110,016,526 - 110,023,839 (-)NCBI
Celera10104,432,228 - 104,439,540 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
PCYT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381781,900,958 - 81,911,399 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1781,900,958 - 81,911,432 (-)EnsemblGRCh38hg38GRCh38
GRCh371779,858,834 - 79,869,275 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361777,455,384 - 77,462,586 (-)NCBINCBI36Build 36hg18NCBI36
Celera1776,464,784 - 76,473,410 (-)NCBICelera
Cytogenetic Map17q25.3NCBI
HuRef1775,262,457 - 75,287,046 (-)NCBIHuRef
CHM1_11779,946,981 - 79,955,542 (-)NCBICHM1_1
T2T-CHM13v2.01782,768,118 - 82,778,559 (-)NCBIT2T-CHM13v2.0
Pcyt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911120,500,888 - 120,508,784 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11120,500,913 - 120,508,762 (-)EnsemblGRCm39 Ensembl
GRCm3811120,610,062 - 120,617,947 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11120,610,087 - 120,617,936 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711120,471,401 - 120,479,204 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611120,426,177 - 120,433,980 (-)NCBIMGSCv36mm8
Celera11132,345,379 - 132,353,183 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1184.33NCBI
Pcyt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555061,256,770 - 1,266,762 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555061,258,993 - 1,266,108 (+)NCBIChiLan1.0ChiLan1.0
PCYT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21998,440,330 - 98,447,591 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan117103,341,093 - 103,348,358 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01776,309,798 - 76,317,054 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11782,010,262 - 82,018,515 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1782,010,262 - 82,018,515 (-)Ensemblpanpan1.1panPan2
PCYT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.19383,714 - 390,164 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl9376,445 - 442,919 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha9985,814 - 992,258 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.09977,032 - 983,475 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl9977,078 - 983,469 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.191,002,181 - 1,008,623 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.091,128,807 - 1,135,219 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.091,207,457 - 1,213,883 (+)NCBIUU_Cfam_GSD_1.0
Pcyt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602994,046 - 1,001,014 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365945,410,948 - 5,417,988 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365945,410,975 - 5,417,958 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PCYT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl121,084,410 - 1,091,029 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1121,084,416 - 1,091,031 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PCYT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11673,777,641 - 73,784,800 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1673,776,092 - 73,784,724 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607745,226,524 - 45,236,947 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pcyt2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480110,746,373 - 10,753,289 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480110,746,551 - 10,753,221 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pcyt2
15 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:377
Count of miRNA genes:177
Interacting mature miRNAs:197
Transcripts:ENSRNOT00000054952, ENSRNOT00000068708
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1051770177107211142Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1051770177107211142Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1053797385107211142Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062057807107057807Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062057807107057807Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
2317029Aia19Adjuvant induced arthritis QTL 192.98joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1066978955107211142Rat
2317039Aia6Adjuvant induced arthritis QTL 64.31joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)1066978955107211142Rat
10450498Bp384Blood pressure QTL 3840.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1067750049107211142Rat
1642980Bp300Blood pressure QTL 300arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068383129107211142Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068420376107211142Rat
2300172Bmd57Bone mineral density QTL 579.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1069738412107211142Rat
2293646Bss25Bone structure and strength QTL 2510.960.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1069738412107211142Rat
2293663Bss33Bone structure and strength QTL 339.340.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1069738412107211142Rat
6893366Bw106Body weight QTL 1060.30.47body mass (VT:0001259)body weight (CMO:0000012)1070199100107211142Rat
70193Mcs7Mammary carcinoma susceptibility QTL 72.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072224939107211142Rat
2298548Neuinf7Neuroinflammation QTL 73.4nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1072224939107211142Rat
2292438Bp311Blood pressure QTL 311arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1076246085107211142Rat
1302404Cia27Collagen induced arthritis QTL 272.60.0045joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)1076452683107211142Rat
4889492Pancm2Pancreatic morphology QTL 23.2pancreatic beta cell morphology trait (VT:0005217)ratio of insulin-positive cell area to total area of splenic region of pancreas (CMO:0001814)1076748906107211142Rat
2303589Bw87Body weight QTL 872body mass (VT:0001259)body weight (CMO:0000012)1081285008107211142Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)1082685200107211142Rat
631538Oia5Oil induced arthritis QTL 5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1087055121107211142Rat
61363Oia3Oil induced arthritis QTL 30.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1087307617107211142Rat
634320Niddm49Non-insulin dependent diabetes mellitus QTL 494.41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1088539139107211142Rat
12880395Cm109Cardiac mass QTL 1090.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)1090404397107211142Rat
12880396Am13Aortic mass QTL 130.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1090404397107211142Rat
12880398Kidm67Kidney mass QTL 670.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1090404397107211142Rat
12880384Cm107Cardiac mass QTL 1070.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)90404397107211142Rat
12880385Cm108Cardiac mass QTL 1080.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)90404397107211142Rat
1579915Bp280Blood pressure QTL 2800.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1090404397107211142Rat
1300137Bp186Blood pressure QTL 1863.57arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1090627439107057807Rat
724530Bp149Blood pressure QTL 1490.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1090627439107211142Rat
1354641Bvd2Brain ventricular dilatation QTL 26.360.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)1093223816107057807Rat
10450493Bp382Blood pressure QTL 3820.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1094759759107211142Rat
2292436Bp310Blood pressure QTL 310arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1094759759107211142Rat
1578663Bss18Bone structure and strength QTL 183.6femur width (VT:1000666)femoral neck width (CMO:0001695)1096703043107057807Rat
1578672Bmd16Bone mineral density QTL 166.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)1096703043107057807Rat

Markers in Region
RH130955  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.210105,896,533 - 105,896,745 (+)MAPPERmRatBN7.2
Rnor_6.010109,796,104 - 109,796,315NCBIRnor6.0
Rnor_5.010109,389,156 - 109,389,367UniSTSRnor5.0
RGSC_v3.410110,009,727 - 110,009,938UniSTSRGSC3.4
Celera10104,439,932 - 104,440,143UniSTS
Cytogenetic Map10q32.3UniSTS
RH142548  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.210105,894,807 - 105,894,915 (+)MAPPERmRatBN7.2
Rnor_6.010109,794,378 - 109,794,485NCBIRnor6.0
Rnor_5.010109,387,430 - 109,387,537UniSTSRnor5.0
RGSC_v3.410110,008,001 - 110,008,108UniSTSRGSC3.4
Celera10104,438,206 - 104,438,313UniSTS
Cytogenetic Map10q32.3UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000054952   ⟹   ENSRNOP00000051835
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl10105,888,775 - 105,896,172 (-)Ensembl
Rnor_6.0 Ensembl10109,788,350 - 109,795,697 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000109346   ⟹   ENSRNOP00000082255
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl10105,888,830 - 105,896,009 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111239   ⟹   ENSRNOP00000090700
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl10105,888,829 - 105,896,161 (-)Ensembl
RefSeq Acc Id: NM_053568   ⟹   NP_446020
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,387,156 - 106,394,468 (-)NCBI
mRatBN7.210105,888,830 - 105,896,142 (-)NCBI
Rnor_6.010109,788,400 - 109,795,712 (-)NCBI
Rnor_5.010109,381,397 - 109,388,794 (-)NCBI
RGSC_v3.410110,002,023 - 110,009,335 (-)RGD
Celera10104,432,228 - 104,439,540 (-)RGD
Sequence:
RefSeq Acc Id: XM_006247935   ⟹   XP_006247997
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,387,150 - 106,394,497 (-)NCBI
mRatBN7.210105,888,769 - 105,896,180 (-)NCBI
Rnor_6.010109,788,348 - 109,795,743 (-)NCBI
Rnor_5.010109,381,397 - 109,388,794 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039087002   ⟹   XP_038942930
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,387,150 - 106,394,266 (-)NCBI
mRatBN7.210105,888,769 - 105,895,916 (-)NCBI
RefSeq Acc Id: XM_039087004   ⟹   XP_038942932
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,387,150 - 106,390,028 (-)NCBI
mRatBN7.210105,888,769 - 105,891,704 (-)NCBI
RefSeq Acc Id: XM_039087005   ⟹   XP_038942933
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,387,962 - 106,394,500 (-)NCBI
mRatBN7.210105,889,636 - 105,896,182 (-)NCBI
RefSeq Acc Id: XM_063270003   ⟹   XP_063126073
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,387,150 - 106,394,266 (-)NCBI
RefSeq Acc Id: XR_005489961
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,389,503 - 106,394,499 (-)NCBI
mRatBN7.210105,888,769 - 105,896,181 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_446020   ⟸   NM_053568
- UniProtKB: Q6AZ30 (UniProtKB/Swiss-Prot),   O88637 (UniProtKB/Swiss-Prot),   A6HLG4 (UniProtKB/TrEMBL),   A0A8I6AET7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006247997   ⟸   XM_006247935
- Peptide Label: isoform X1
- UniProtKB: A6HLG3 (UniProtKB/TrEMBL),   A0A8L2QPS4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000051835   ⟸   ENSRNOT00000054952
RefSeq Acc Id: XP_038942930   ⟸   XM_039087002
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZT93 (UniProtKB/TrEMBL),   A0A8I6AET7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038942932   ⟸   XM_039087004
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038942933   ⟸   XM_039087005
- Peptide Label: isoform X5
- UniProtKB: A0A8I6AET7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000082255   ⟸   ENSRNOT00000109346
RefSeq Acc Id: ENSRNOP00000090700   ⟸   ENSRNOT00000111239
RefSeq Acc Id: XP_063126073   ⟸   XM_063270003
- Peptide Label: isoform X3
Protein Domains
Cytidyltransferase-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O88637-F1-model_v2 AlphaFold O88637 1-404 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697970
Promoter ID:EPDNEW_R8493
Type:initiation region
Name:Pcyt2_1
Description:phosphate cytidylyltransferase 2, ethanolamine
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.010109,795,716 - 109,795,776EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619970 AgrOrtholog
BioCyc Gene G2FUF-22403 BioCyc
BioCyc Pathway PWY-7782 [plasmalogen biosynthesis] BioCyc
  PWY4FS-6 [phosphatidylethanolamine biosynthesis II] BioCyc
BioCyc Pathway Image PWY-7782 BioCyc
  PWY4FS-6 BioCyc
Ensembl Genes ENSRNOG00000036684 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00055030074 UniProtKB/Swiss-Prot
  ENSRNOG00060020950 UniProtKB/Swiss-Prot
  ENSRNOG00065004125 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000054952.5 UniProtKB/TrEMBL
  ENSRNOT00000109346.1 UniProtKB/TrEMBL
  ENSRNOT00000111239 ENTREZGENE
  ENSRNOT00000111239.1 UniProtKB/TrEMBL
  ENSRNOT00055052324 UniProtKB/Swiss-Prot
  ENSRNOT00060036735 UniProtKB/Swiss-Prot
  ENSRNOT00065006087 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.620 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7111560 IMAGE-MGC_LOAD
InterPro CCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_trans-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ect1/PCYT2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rossmann-like_a/b/a_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:89841 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:93299 IMAGE-MGC_LOAD
NCBI Gene 89841 ENTREZGENE
PANTHER ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR45780 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CTP_transf_like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pcyt2 PhenoGen
RatGTEx ENSRNOG00000036684 RatGTEx
  ENSRNOG00055030074 RatGTEx
  ENSRNOG00060020950 RatGTEx
  ENSRNOG00065004125 RatGTEx
Superfamily-SCOP Nucleotidylyl transferase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZT93 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AET7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QPS4 ENTREZGENE, UniProtKB/TrEMBL
  A6HLG3 ENTREZGENE, UniProtKB/TrEMBL
  A6HLG4 ENTREZGENE, UniProtKB/TrEMBL
  A6HLG5_RAT UniProtKB/TrEMBL
  O88637 ENTREZGENE, UniProtKB/Swiss-Prot
  Q6AZ30 ENTREZGENE
UniProt Secondary Q6AZ30 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-26 Pcyt2  phosphate cytidylyltransferase 2, ethanolamine      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Pcyt2  phosphate cytidylyltransferase 2, ethanolamine      Symbol and Name status set to provisional 70820 PROVISIONAL