Sv2c (synaptic vesicle glycoprotein 2c) - Rat Genome Database

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Gene: Sv2c (synaptic vesicle glycoprotein 2c) Rattus norvegicus
Analyze
Symbol: Sv2c
Name: synaptic vesicle glycoprotein 2c
RGD ID: 619718
Description: Predicted to enable transmembrane transporter activity. Predicted to be involved in regulation of synaptic vesicle exocytosis. Located in synaptic vesicle. Is active in synaptic vesicle membrane. Orthologous to human SV2C (synaptic vesicle glycoprotein 2C); PARTICIPATES IN cell-extracellular matrix signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: synaptic vesicle protein 2C
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8228,967,631 - 29,163,168 (-)NCBIGRCr8
mRatBN7.2227,232,933 - 27,428,479 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl227,232,933 - 27,428,477 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx234,272,667 - 34,465,181 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0232,372,766 - 32,565,287 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0227,188,759 - 27,389,783 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0226,495,757 - 26,707,691 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl226,501,833 - 26,699,333 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0245,631,737 - 45,828,663 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4226,326,862 - 26,555,019 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1226,247,230 - 26,475,388 (-)NCBI
Celera223,293,289 - 23,483,743 (-)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses. Boyken J, etal., Neuron. 2013 Apr 24;78(2):285-97. doi: 10.1016/j.neuron.2013.02.027.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. SVOP, an evolutionarily conserved synaptic vesicle protein, suggests novel transport functions of synaptic vesicles. Janz R, etal., J Neurosci 1998 Nov 15;18(22):9269-81.
4. The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves. Mahrhold S, etal., FEBS Lett. 2006 Apr 3;580(8):2011-4. Epub 2006 Mar 7.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Identification of the synaptic vesicle glycoprotein 2 receptor binding site in botulinum neurotoxin A. Strotmeier J, etal., FEBS Lett. 2014 Apr 2;588(7):1087-93. doi: 10.1016/j.febslet.2014.02.034. Epub 2014 Feb 25.
12. Synaptotagmin-2, and -1, linked to neurotransmission impairment and vulnerability in Spinal Muscular Atrophy. Tejero R, etal., Hum Mol Genet. 2016 Aug 29. pii: ddw297.
Additional References at PubMed
PMID:10625067   PMID:12687700   PMID:15866046   PMID:16306227   PMID:16543415  


Genomics

Comparative Map Data
Sv2c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8228,967,631 - 29,163,168 (-)NCBIGRCr8
mRatBN7.2227,232,933 - 27,428,479 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl227,232,933 - 27,428,477 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx234,272,667 - 34,465,181 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0232,372,766 - 32,565,287 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0227,188,759 - 27,389,783 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0226,495,757 - 26,707,691 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl226,501,833 - 26,699,333 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0245,631,737 - 45,828,663 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4226,326,862 - 26,555,019 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1226,247,230 - 26,475,388 (-)NCBI
Celera223,293,289 - 23,483,743 (-)NCBICelera
Cytogenetic Map2q12NCBI
SV2C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38575,847,464 - 76,353,939 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl576,083,383 - 76,353,939 (+)EnsemblGRCh38hg38GRCh38
GRCh37575,379,208 - 75,649,764 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36575,415,061 - 75,657,172 (+)NCBINCBI36Build 36hg18NCBI36
Build 34575,526,658 - 75,661,645NCBI
Celera571,320,469 - 71,515,084 (+)NCBICelera
Cytogenetic Map5q13.3NCBI
HuRef570,632,037 - 70,829,092 (+)NCBIHuRef
CHM1_1574,860,605 - 75,054,059 (+)NCBICHM1_1
T2T-CHM13v2.0576,328,570 - 76,835,704 (+)NCBIT2T-CHM13v2.0
Sv2c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391396,091,102 - 96,270,837 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1396,091,102 - 96,269,085 (-)EnsemblGRCm39 Ensembl
GRCm381395,959,443 - 96,132,577 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1395,954,594 - 96,132,577 (-)EnsemblGRCm38mm10GRCm38
MGSCv371396,729,398 - 96,902,532 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361397,060,142 - 97,233,276 (-)NCBIMGSCv36mm8
Celera1399,577,609 - 99,753,046 (-)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1350.47NCBI
Sv2c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542524,496,434 - 24,683,179 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542524,489,304 - 24,682,555 (-)NCBIChiLan1.0ChiLan1.0
SV2C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2438,969,968 - 39,223,327 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1537,123,598 - 37,376,956 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0538,969,056 - 39,222,300 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1539,566,207 - 39,836,653 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl539,566,207 - 39,836,852 (-)Ensemblpanpan1.1panPan2
SV2C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1330,232,892 - 30,440,046 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl330,232,710 - 30,440,327 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha331,469,780 - 31,678,170 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0330,156,170 - 30,363,724 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl330,156,894 - 30,363,969 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1330,087,278 - 30,241,695 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0330,066,666 - 30,270,719 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0330,437,678 - 30,645,896 (-)NCBIUU_Cfam_GSD_1.0
Sv2c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213190,039,748 - 190,265,745 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936549590,978 - 765,741 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936549592,975 - 819,252 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SV2C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl284,996,716 - 85,236,130 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1284,996,697 - 85,235,827 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2286,622,023 - 86,679,582 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SV2C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1470,358,164 - 70,601,764 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl470,358,236 - 70,601,242 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604919,160,261 - 19,408,353 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sv2c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624869669,391 - 831,138 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624869611,873 - 838,014 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sv2c
2076 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:48
Count of miRNA genes:42
Interacting mature miRNAs:44
Transcripts:ENSRNOT00000024459
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631682Bp115Blood pressure QTL 1154.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2137410502Rat
738010Lnnr3Liver neoplastic nodule remodeling QTL 32.94liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)2141244106Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)25873687102844969Rat
1600379Mcs18Mammary carcinoma susceptibility QTL 182.6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2788777242804738Rat
738012Anxrr3Anxiety related response QTL 33.8exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)2902351954023519Rat
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21159110056591100Rat
1578664Bmd9Bone mineral QTL density 95femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)21185206249003364Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21649174061491740Rat
1357990Ael1Aortic elastin QTL 13.10.00091aorta elastin amount (VT:0003905)aortic elastin21907682564076825Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22030467265304672Rat
2300168Bmd47Bone mineral density QTL 476.60.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)22066244865662448Rat
10402051Gdil2Gastrointestinal dilation QTL 2enteric ganglion morphology trait (VT:0001045)length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)22490385374786777Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)225413423143657569Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)22691781781754745Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)22691781781754745Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22691781781754745Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)226917817127469484Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)226917817136917119Rat
1331764Bp205Blood pressure QTL 2053.476arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)22699957143154682Rat
1643006Pain1Pain QTL 13.630.005mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)22699957148268661Rat
9590095Sffal3Serum free fatty acids level QTL 36.780.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)22715716072157160Rat

Markers in Region
BE108455  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2227,423,442 - 27,423,604 (+)MAPPERmRatBN7.2
Rnor_6.0226,694,240 - 26,694,401NCBIRnor6.0
Rnor_5.0245,823,627 - 45,823,788UniSTSRnor5.0
RGSC_v3.4226,549,983 - 26,550,144UniSTSRGSC3.4
Celera223,478,693 - 23,478,854UniSTS
RH 3.4 Map213.3UniSTS
Cytogenetic Map2q12UniSTS
RH139477  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2227,429,858 - 27,430,064 (+)MAPPERmRatBN7.2
Rnor_6.0226,700,656 - 26,700,861NCBIRnor6.0
Rnor_5.0245,830,043 - 45,830,248UniSTSRnor5.0
RGSC_v3.4226,556,399 - 26,556,604UniSTSRGSC3.4
Celera223,485,123 - 23,485,328UniSTS
RH 3.4 Map213.3UniSTS
Cytogenetic Map2q12UniSTS
AI179314  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2227,298,492 - 27,298,648 (+)MAPPERmRatBN7.2
Rnor_6.0226,568,693 - 26,568,848NCBIRnor6.0
Rnor_5.0245,698,340 - 45,698,495UniSTSRnor5.0
RGSC_v3.4226,424,057 - 26,424,212UniSTSRGSC3.4
Celera223,354,862 - 23,355,017UniSTS
RH 3.4 Map213.3UniSTS
Cytogenetic Map2q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 37
Low 36 10 2 2 3 3 35 12 31 8 3
Below cutoff 3 6 15 7 17 7 5 6 2 10 10 3 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000024459   ⟹   ENSRNOP00000024459
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl227,232,933 - 27,428,477 (-)Ensembl
Rnor_6.0 Ensembl226,501,833 - 26,699,333 (-)Ensembl
RefSeq Acc Id: NM_031593   ⟹   NP_113781
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8228,967,631 - 29,163,168 (-)NCBI
mRatBN7.2227,232,933 - 27,428,479 (-)NCBI
Rnor_6.0226,502,115 - 26,699,276 (-)NCBI
Rnor_5.0245,631,737 - 45,828,663 (-)NCBI
RGSC_v3.4226,326,862 - 26,555,019 (-)RGD
Celera223,293,289 - 23,483,743 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_113781 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC78628 (Get FASTA)   NCBI Sequence Viewer  
  CAG34351 (Get FASTA)   NCBI Sequence Viewer  
  EDM10107 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000024459
  ENSRNOP00000024459.3
  ENSRNOP00055039787
  ENSRNOP00060042078
  ENSRNOP00065034527
GenBank Protein Q9Z2I6 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_113781   ⟸   NM_031593
- UniProtKB: Q9Z2I6 (UniProtKB/Swiss-Prot),   A6I4Z9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000024459   ⟸   ENSRNOT00000024459
Protein Domains
Major facilitator superfamily (MFS) profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z2I6-F1-model_v2 AlphaFold Q9Z2I6 1-727 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619718 AgrOrtholog
BioCyc Gene G2FUF-54786 BioCyc
Ensembl Genes ENSRNOG00000018094 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055027955 UniProtKB/Swiss-Prot
  ENSRNOG00060029133 UniProtKB/Swiss-Prot
  ENSRNOG00065024595 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000024459 ENTREZGENE
  ENSRNOT00000024459.7 UniProtKB/Swiss-Prot
  ENSRNOT00055048390 UniProtKB/Swiss-Prot
  ENSRNOT00060050561 UniProtKB/Swiss-Prot
  ENSRNOT00065042223 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1250.20 UniProtKB/Swiss-Prot
  E3 ubiquitin-protein ligase SopA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MFS general substrate transporter like domains UniProtKB/TrEMBL
InterPro 5peptide_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MFS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MFS_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MFS_sugar_transport-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sugar_transporter_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SV2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29643 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 29643 ENTREZGENE
PANTHER SYNAPTIC VESICLE GLYCOPROTEIN 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SYNAPTIC VESICLE GLYCOPROTEIN 2C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam MFS_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pentapeptide_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sugar_tr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sv2c PhenoGen
PROSITE MFS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUGAR_TRANSPORT_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000018094 RatGTEx
  ENSRNOG00055027955 RatGTEx
  ENSRNOG00060029133 RatGTEx
  ENSRNOG00065024595 RatGTEx
Superfamily-SCOP MFS general substrate transporter UniProtKB/TrEMBL
  Pentapeptide repeat-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF103473 UniProtKB/Swiss-Prot
UniProt A6I4Z9 ENTREZGENE, UniProtKB/TrEMBL
  Q9Z2I6 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Sv2c  synaptic vesicle glycoprotein 2c    synaptic vesicle protein 2C  Name updated 1299863 APPROVED
2002-08-07 Sv2c  synaptic vesicle protein 2C      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in synaptic vesicles 634114
gene_function vesicular transporter of a charged molecule 634114