Hexim2<sup>em4Mcwi</sup> (HEXIM P-TEFb complex subunit 2; zinc finger nuclease induced mutant 4, Medical College of Wisconsin) - Rat Genome Database

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Gene: Hexim2em4Mcwi (HEXIM P-TEFb complex subunit 2; zinc finger nuclease induced mutant 4, Medical College of Wisconsin) Rattus norvegicus
Analyze
Symbol: Hexim2em4Mcwi
Name: HEXIM P-TEFb complex subunit 2; zinc finger nuclease induced mutant 4, Medical College of Wisconsin
RGD ID: 5144095
Description: This allele was made by ZFN mutagenesis. The resulting mutation is a 10-bp frameshift deletion in exon 3 (del 798-807)
Type: allele  of Hexim2  
Previously known as: hexamethylene bis-acetamide inducible 2; zinc finger nuclease induced mutant 4, Medical College of Wisconsin; Hexim2^[em4Mcwi]; Hexim2em4Mcwi
Is Marker For: Strains:   SS-Hexim2em4Mcwi  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Cytogenetic Map10 RGD


References

References - curated
# Reference Title Reference Citation
1. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2. PhysGen Knockouts PhysGen Knockout strains

Genomics

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Hexim2em4Mcwi-var1 chr10 91217079 91222841 GCCTTGGCAGAGCTCGGCCTCAGGATCTCGTCCCGGTGGAGGTACAGCAAAGGGGAAGCCGTCTTACTGGCCTTTCCTCTGCTGAGATCACGGGAAATACGCGGTAATTACCCCCAAAAACCCGCTCTCAAAGGCGAGGCGGCTAGGTTGCCGGGACGGTTTGAGGACTGGGCTCGGCCGGGGAGACGCCAACCTTCACCCTTCCCGGCCCCCGACCCAACTCCCCGCCGTCTCCCGGCGCCGCCACTTCAGGCAGCCCACTCGGCCCGGCCTCTCCCCGCGCCCGGACCACCCCCCATGGGGTGCTCTCACTGCGCAGCGAGTCCCTCCGCTGCCTCCTCCCAGCCCAAAATGGCGGCGGCGGCGGCCACCGAGCTGCTCGTCGCCTTCCTCTAGGCTAGGGAATCCCTCCGCGCATAAGCCCCGCCCCTGTGAGCCGGATCTAGATTTCTCTCTGGTAAAGACTAACGCCATCAATGAACTCTTTAATTGAATCTTGACAGGGCGGGTCCAGTTGTGCTTCCGCACAGCTAGTTGTTGACAAAAGTAGGAAGACTGGCAGACAAGCGACCCAATCAAAAGAGAGATCGGTGAGCGCGGGACGTCCACGCAAAAGCAGATAGGTTTTGGCGTTCTTAGGCATGGTTGTTGACGTAATGGGAGCTTGAAAGTATCCTGGGCTGCTTTCCTAGTGTCGAAGAACTACAACCCCCAGCAGTCACTGCGCTGCCAGGCTGTACTCTTCGCCTCTCCACCTCCCCCCATCTTAGTGCTTGAGCGGCTTGGCCAGAGCTGCTGCTACTGCAGCAAGAGGTAGGGCTGAGGCGTTGAGAATTTCATGGACAGGCGGTCGCACAGAAAGACACACAGAGGTAGTGGTGTACACTAAGCCCTTGACAGCAAATAGGTCAGTCCCACCTTTGCTAAACCTCCCTTCCATGACTATTTTCCTTCTTCCAAGAAATCCATTTTTACTCCCATTTGATTTTTTTTTTCCTGTCAGTTGCATGTAGTATGAAGACCTCTTTCCTCTATTTCCCCATCCCTTGAGGCAGGAGAGTTGCCGTCCTGCCCCTGTAGACAAAAAGACTTTAGCCATAGGCTCTGACCGGGTCCCAGCCTAGGGAGGTTGAAGGTGGTCAAGATAGGGACTTCCAGGAGCTACAGACCCACCCCATCCACAGCTTCCCCCAAGCAGTTTCCTTTCTGCGTGACAGAGTTTAGGCCTACCTTCCTAACTGCCAGCCTGATCTTTACTTATTAGGAGAGCAGATGCCCGGGGGCCTGAGGGAACAGGATTGGAAAGAGGGTCTCGCTCTCCCATTTGGTCCCTTGCTGGCTAGAAGTGTGAAAACGAGGGTACGGAAGCAACCTTCAGAGTCTTCATTTGAAAGTGAAGCCCATGCAGGTCTGGGGCCACAAAATGGCTGCTGATGCTGGGACAAACAATTGCTGACCAACCAGATTCTGCCTGAGGACTTAGGTTTCTGTTGTTGTTCAAAGCAGGTGACAGTAGTTAAAGGCATCATCTACTGAAAGAGTAGGAGAAGATGGCCACTCTGAACCATACCAACTGTAATTCAGCGTCACCAGCTGCTCTGGAGAAGACGAAGGTAAGTACTCACCCCTCCCAGCCACCTGAAAGCCCTAAACACGGGGTCAAATAGCTGAAATCCTAGGGGTTTTTTGTTCTGTCTTGTTTGTTTGTTGGTAGATTTAGAAAACCACTGTTTTATTTTATTTTTGTTTGTTTGAGACAGGGGTTTTTCTGTGTATCCCCAGCTGGTCTCGAACTTGCAACAACATACTTCTTCAGCTTTATAAGTGCTAAAATTATAGCCTGCACCACCTCACCCAGCTAGAAAGCCAGTGTTTTAAATGAGACTGTACCGTGCTCTGGGAAATAGGCCAGAATGTGATTCAATGATATCTCATGAATTCCTAAAAGCTCTTCAAGGTAGATGTTATTTCCAATAGACAGAAGCTAAGGTTTGGAGAGCTGCAATACCTTTTCCAGAATCACCCAGCCTGTAAGCAACAAAATCCCACTTTCCATTTAGGGTCTTAAGATAACAGAACCTTGACAGGTGACCTCAAGGACAAATAACCTGGTTAGAGATTTGAGCTTCAAAAGCATTTTTTTTTCAGGCTGAGAACCAAGAATGAAACAGGACAAGAGGTTTTGGTGTACAGGTTGGCAGGCAGGGCAGGAAAACCTCAGAAGAGAGAGAGAGAAAGCTCCTAAGTCCTCAGTAAATGGCACCTTACTATGGGCCGACATTGGGAACCCACAGAGTCGGGCCCACACTGTCTCGAGTTGGCCTTCTTTACCCATCACCACAGCGCCAAAATAGCAGAGAGCCAGAAAGCAGAGAGTTGGTTTCTGTTGTTGTTGATTTTGCAGTGCTGGGGATTGAACCCAGGGCCTTGCAAATGCTAGAAAAATGCTTTATCATGGAGCTAGACCCCCAGTTCTTTGTTTTTGTTTGCTGGTTTTTGGCTTTATTTTTTTTTTTTTTCTTTTCCTTTTTTCGGAGCTGGGGACCGAACCCAGGGCCTTGCGCTTGCTAGGCAAGCGCTCTACCACTGAGCTAAATTCCCAACCCCTTTGGCTTTATTTTTTTTTGACAGCGTTTCTCTGCGTAACAGCCCTGACTGCCCTGAAACTCACTTTGGAGATCAGGCTGGCCTGTAACTTAAGAGATCCACTTCCTGAGTGCTGGCATTATGTGCGTGTGTCACGGTGTTTAGCTCAGAGAGGCTTTTAACCCATCCTGCCTAACCTATTCCAGGGTTTCTTAGTGACGTGCCAAGGCTAGCAGGTTGAGAGGGGGCGGGCTACAGAGCTTATCTTTACATTGACGGTGGTGGAGGGGCAAAGCTGTCTTGGTTTTAGTCAGGCATCACTAGGGGACTAAGGCTGGGAACAGGGAAACGACAATACCATACACTAAGCTGTCCTTAATTCCTGGTACTGTGTGTCTCTAGGTGGGCCACAGACATTTTAGTTGGTCGAAGCCACCAGTTAGACAAGGCCAGTCCCTTATGATTGGTAATATTCCTGCAGGTGAAGGACCATGGCACACAACACACACACACACACACACACACACACACACACACACGCGCGCGCTCATTAGGGTGTGTCTGTATACTCACTTACATAGTAAGTAAATAATACAAATTTTAAAAGTAACCCTGCTCAGATGCCGTGATGTGTAAAACAGCCGGTGATAGTGGATATTATTAGAAATCTCCCAAACCACAAACATAGAGCAATTCGTTCCCTATCCTCACACCCAGGACTCCCACCCTCACCACACAGATAAGCAGATGCCCCTTGCATGCACTCCCTCCCTCCCTCTATCTCTCTCCCTCTCTTCTTCCTCCCCCAAGGTCTCATCTTTGTATAGCCCTGGCTTGCCTGGAACAGGCTGGCCTCAGACTCATCCGCTTGCCTCTTGTCACCAAGCCCTGGGATTGATGGATTCTTTCTCTCCCTCTTTAAAGCCTTGAAATCTCACTGCAACCTCCCCTTGGTTAGGGCCTTGCACAGTACATAAATAAACAACCTTGTGTTCACTGAGCAAGGGGTAAAATGTTGCATTCTCAGGGGATGAAGATACATGGTAAGTCGTAACACACCAGGTGCTATCTGTGAGGTTGCCTGTGCGACAAGGTAGAGTAGCTGGGGGAATGGGAGAGCCACTGTCATAGGATCTTCAGGAAGAGCATCACTGAAGAGGCAACATTAGGCCTGAAGCATGGGGAACAGGAAAGGGTACACCATGCAGAGAGCTGAAAGCAGGATTAGTTACCTAATTTTCAGGGAGGGGGCAGGAAATCCCTGTTCAAAAGTTATTAAGTTCAACCCCTGACCTATGATCCTAGCTACTCTGGAGGCCGAGGCAGGTAGATTATAAGTTTGAGACTTGCTTGGATAGAGGGTGAGTTCAAATTCAGCCTGGAAAACTTAGTGAGATTCTATTTCCAAACAAAAGCTAAAGGAGTAGGAATATAGCAGAATGACATCACGCCCGCTGAGCATGCGTGAGACTCTGGCCTGGATAAAGGTATGAAGTTCAGAGCTAGTCATAGTTTCACGTACCTGTTATTGAGGCTGAGGCAGGAGGATGGTGAGTTTGAGACCAGCCTGAGCTACACTGGGAAGACCCCAATTTCAAGGATAGCAGAGCAGTAAACTGAGTGTGAATCCCTTCTGAATGTGGGTACCTGTGGAGGTGTTGAGATAGCCCAGGCTGTCCTTGATCCTGGTTTGAAGTCCTGACTCTCCTGCCTTTTCACCTTAGTGCTGGGATTTACAGTTCTCCACTACCACATGTAGCCTCCCTGTCTTTTCATTCGACTAGTGCTTGTGGAATGCTACTCTAGGTCTGGTATCATTCTGGACTTTGAAATGACCAGCATCTCAGTTAATGGCTTCCCAAGATGCATGAAACCCTGGCTTGCATCCCTAGCGCTGCAGAAACCCAGCATGGTGGCACATATTGTAGCTCAGCCTTCAGGAGGTAGAGGCAGGCAGATCAGAGGTTCAAGGTCATCTTTAGTTCCTCAAGTGAGTTCAAAGCCAACCTGGTCTGTGGTGATGCTATGTCAAAAGAAAAAAAAAAGTGAAGGGGGAGGGGCTAAATAGTGACCACTTGAGGCAAGTGTGAGGCGGCTGGCCGGGCTGGGAAGGACTCCTCTCCCAGAGAAAGGCTATCTGACCCACCCTCCTTCCTCTCTCTAGACTTCTGGTGGTCTTCGGAGCCCCCAGATAGCCCATGAGCCTCATGACTTCGGTGGTTCCCTGCTTCTGCAACCAGGAAGGGAGATTCAATCAGAGGATGAAGGGACTGCCCCAGCCGGCGATGGCTCAAGTTGTAACATTAGGGGTTCTCGAACCCAGAGCCCAGGGGGCTGTTCAGTGGAGGCGGTGCTGGCCCGGAAGAAACACCGTAGGCGGCCATCAAAACGCAAGCGGCACTGGCGGCCATACTTGGAGCTGAGCTGGGCTGAGAAGCAACAGCGGGATGAGAGGCAGAGCCAGAGGGCCTCTCGGGTCCGCCAGGAGATGTTCGCCAAAGGCCAGCCCCTGGCACCCTACAACACCACCCAGTTCCTTATGAATGACCGTGACCTGGAGGAGCCTAACCTCGATGTGCTCCATGGGCCCTCCCACGCGGACTCCGGTGGGGAGAATGAAGCAGGGGACAGTGATGGGCTAGGGCGAGCGCATGGGGAATTTCAGCAGAGGGACTTCTCAGAGGCCTATGAGCGGTACCACACTGAGAGCCTTCAGGGCCGCAGCAAGCAGGAGCTGGTGCGAGACTACCTGGATCTAGAGAGGCGTCTGTCCCAGGCTGAGCAGGAAACTCGGAGGCTTCAGCAGCTTCAGGGACGCCCCAGCAGGCAACCCTGCCAGCAGGTGGAAGAGCTGGCGGCTGAGGTGGAGAGGCTCCGAACTGAAAACCAGCGACTTCGGCAGGAGAACGAGATGTGGAACCGAGAGGGCAGCTACTGTGACCGGGAGAAGACAGCCGCAGAAGGGACCCCTCGGCCCAAGGATGAGGCCCCACTTCAGACCCGCTCGGGCCAGCTGGGTCACAGGGAGGCAGGTGACAGATGAAAGCTACTCCCAGCATACCTGTCTCCACTGAGAACTGCTAAGACAAGGTCAGAGTTTCCCTGCCATTTTCACTGTTGGGTCTTTATTGTCATCTCACTTTTTACCAGAGCAATTAAATGGCCTTGTGAAATCCA - deletion Rnor_6.0

Related Rat Strains
The following Strains have been annotated to Hexim2em4Mcwi
SS-Hexim2em4Mcwi    


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-03 Hexim2em4Mcwi  HEXIM P-TEFb complex subunit 2; zinc finger nuclease induced mutant 4, Medical College of Wisconsin  Hexim2em4Mcwi  hexamethylene bis-acetamide inducible 2; zinc finger nuclease induced mutant 4, Medical College of Wisconsin  Name changed 629549 APPROVED