Spt1 (salivary protein 1) - Rat Genome Database

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Gene: Spt1 (salivary protein 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Spt1
Name: salivary protein 1
RGD ID: 3754
Description: INTERACTS WITH ammonium chloride; bexarotene; Cuprizon
Type: protein-coding
RefSeq Status: VALIDATED
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87136,908,216 - 136,918,249 (-)NCBIGRCr8
mRatBN7.27134,914,177 - 134,924,215 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7134,914,177 - 134,924,157 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7136,578,227 - 136,588,888 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07138,807,620 - 138,818,281 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07138,899,857 - 138,909,904 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07145,325,004 - 145,338,152 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7145,325,004 - 145,338,152 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07143,110,487 - 143,121,405 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47142,745,352 - 142,756,937 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17142,825,540 - 142,837,126 (-)NCBI
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Rapid evolution of variants in a rodent multigene family encoding salivary proteins. Dickinson DP, etal., Mol Biol Evol 1989 Jan;6(1):80-102.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data

Genomics

Variants

.
Variants in Spt1
60 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:111
Count of miRNA genes:81
Interacting mature miRNAs:84
Transcripts:ENSRNOT00000055268
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7119513385135012528Rat

Markers in Region
BI284004  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27134,830,611 - 134,831,557 (+)MAPPERmRatBN7.2
mRatBN7.27134,922,426 - 134,923,375 (+)MAPPERmRatBN7.2
Rnor_6.07145,574,251 - 145,575,199NCBIRnor6.0
Rnor_6.07145,336,371 - 145,337,319NCBIRnor6.0
Rnor_5.07143,353,506 - 143,354,454UniSTSRnor5.0
Rnor_5.07143,119,624 - 143,120,572UniSTSRnor5.0
RGSC_v3.47142,755,156 - 142,756,104UniSTSRGSC3.4
RH 3.4 Map71065.0UniSTS
Cytogenetic Map7q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system renal system reproductive system respiratory system
High
Medium
Low 1 2
Below cutoff 2 3 16 1 21 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000055268   ⟹   ENSRNOP00000052143
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7145,325,004 - 145,338,152 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000074622   ⟹   ENSRNOP00000066140
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7134,914,177 - 134,924,157 (-)Ensembl
RefSeq Acc Id: NM_019171   ⟹   NP_062044
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87136,908,216 - 136,918,249 (-)NCBI
mRatBN7.27134,914,177 - 134,924,215 (-)NCBI
Rnor_6.07145,325,004 - 145,338,152 (-)NCBI
Rnor_5.07143,110,487 - 143,121,405 (-)NCBI
RGSC_v3.47142,745,352 - 142,756,937 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_062044 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA42174 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000052143.2
  ENSRNOP00000066140
  ENSRNOP00000066140.2
Reference Protein Sequences
RefSeq Acc Id: NP_062044   ⟸   NM_019171
- Peptide Label: precursor
- UniProtKB: M0R9H2 (UniProtKB/TrEMBL),   E9PU79 (UniProtKB/TrEMBL),   Q63557 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000052143   ⟸   ENSRNOT00000055268
RefSeq Acc Id: ENSRNOP00000066140   ⟸   ENSRNOT00000074622

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R9H2-F1-model_v2 AlphaFold M0R9H2 1-91 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3754 AgrOrtholog
BioCyc Gene G2FUF-31855 BioCyc
Ensembl Genes ENSRNOG00000036825 Ensembl
  ENSRNOG00000064464 UniProtKB/TrEMBL
  ENSRNOG00000066132 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000055268.4 UniProtKB/TrEMBL
  ENSRNOT00000074622 ENTREZGENE
  ENSRNOT00000074622.2 UniProtKB/TrEMBL
KEGG Report rno:29229 UniProtKB/TrEMBL
NCBI Gene 29229 ENTREZGENE
PhenoGen Spt1 PhenoGen
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000036825 RatGTEx
  ENSRNOG00000064464 RatGTEx
  ENSRNOG00000066132 RatGTEx
TIGR TC228723
UniProt E9PU79 ENTREZGENE, UniProtKB/TrEMBL
  M0R9H2 ENTREZGENE
  Q63557 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary M0R9H2 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Spt1  salivary protein 1    salivary protein 1   Name updated 1299863 APPROVED
2002-06-10 Spt1  salivary protein 1       Name updated 70584 APPROVED