Gene: Scn10a (sodium voltage-gated channel alpha subunit 10) Rattus norvegicus
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Symbol: Scn10a
Name: sodium voltage-gated channel alpha subunit 10
Description: ENCODES a protein that exhibits voltage-gated sodium channel activity; ion channel binding (ortholog); INVOLVED IN odontogenesis of dentin-containing tooth; sensory perception of pain; sodium ion transport; PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH Hyperalgesia; Sciatic Neuropathy; Atrial Fibrillation (ortholog); FOUND IN clathrin complex; integral component of membrane; axon (ortholog); INTERACTS WITH (+)-trans-(S)-allethrin; allethrin; benzo[a]pyrene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Na(V)1.8; Nav1.8; peripheral nerve sodium channel 3; PN3; sensory neuron sodium channel; sodium channel protein type 10 subunit alpha; sodium channel protein type X subunit alpha; sodium channel type X alpha polypeptide; sodium channel voltage-gated type X alpha polypeptide; sodium channel, voltage-gated, type 10, alpha polypeptide; sodium channel, voltage-gated, type X, alpha; sodium channel, voltage-gated, type X, alpha polypeptide; sodium channel, voltage-gated, type X, alpha subunit; voltage-gated sodium channel subunit alpha Nav1.8
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08128,298,593 - 128,416,896 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.08127,503,061 - 127,620,197 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.48124,578,222 - 124,690,458 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18124,597,959 - 124,710,195 (-)NCBI
Celera8118,500,856 - 118,611,564 (-)NCBI
Cytogenetic Map8q32NCBImapview
Model


Disease Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Scn10a
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 3629
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-11-22
Status: ACTIVE