Gene: Scn10a (sodium voltage-gated channel alpha subunit 10) Rattus norvegicus
Symbol: Scn10a
Name: sodium voltage-gated channel alpha subunit 10
Description: ENCODES a protein that exhibits voltage-gated sodium channel activity; ion channel binding (ortholog); INVOLVED IN odontogenesis of dentin-containing tooth; sensory perception of pain; sodium ion transport; PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH Hyperalgesia; Sciatic Neuropathy; Atrial Fibrillation (ortholog); FOUND IN clathrin complex; integral component of membrane; axon (ortholog); INTERACTS WITH (+)-trans-(S)-allethrin; allethrin; benzo[a]pyrene
Type: protein-coding
Also known as: Na(V)1.8; Nav1.8; peripheral nerve sodium channel 3; PN3; sensory neuron sodium channel; sodium channel protein type 10 subunit alpha; sodium channel protein type X subunit alpha; sodium channel type X alpha polypeptide; sodium channel voltage-gated type X alpha polypeptide; sodium channel, voltage-gated, type 10, alpha polypeptide; sodium channel, voltage-gated, type X, alpha; sodium channel, voltage-gated, type X, alpha polypeptide; sodium channel, voltage-gated, type X, alpha subunit; voltage-gated sodium channel subunit alpha Nav1.8
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.08128,298,593 - 128,416,896 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.08127,503,061 - 127,620,197 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.48124,578,222 - 124,690,458 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18124,597,959 - 124,710,195 (-)NCBI
Celera8118,500,856 - 118,611,564 (-)NCBI
Cytogenetic Map8q32NCBImapview

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Scn10a
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 3629
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-10-04
Status: ACTIVE