Gene: Ptgs1 (prostaglandin-endoperoxide synthase 1) Rattus norvegicus
Symbol: Ptgs1
Name: prostaglandin-endoperoxide synthase 1
Description: ENCODES a protein that exhibits lipid binding; prostaglandin-endoperoxide synthase activity (ortholog); INVOLVED IN aging; learning; maintenance of blood-brain barrier; PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH Alzheimer Disease; Anaphylaxis; Arthritis, Experimental; FOUND IN cytoplasm; nuclear envelope; extracellular exosome (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,4,6-trinitrobenzenesulfonic acid; 2-arachidonoylglycerol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: COX-1; Cox-3; Cox1; Cox3; cyclooxygenase 1; cyclooxygenase 3; cyclooxygenase-1; PGH synthase 1; PGHS-1; PHS 1; prostaglandin G/H synthase 1; prostaglandin G/H synthase and cyclooxygenase; prostaglandin H2 synthase 1; prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.0315,560,685 - 15,582,339+NCBI
Rat Cytogenetic Map3p11 NCBI
RGSC Genome Assembly v5.0320,869,915 - 20,891,512+NCBI
RGSC Genome Assembly v3.4315,343,832 - 15,365,412+NCBI
Rat Celera Assembly314,295,836 - 14,317,392+NCBI
Genome Assembly 3.1315,240,203 - 15,261,784+NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences