Gene: Plcb4 (phospholipase C, beta 4) Rattus norvegicus
Symbol: Plcb4
Name: phospholipase C, beta 4
Description: ENCODES a protein that exhibits mitogen-activated protein kinase binding; INVOLVED IN negative regulation of potassium ion transport; PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; protein kinase C (PKC) signaling pathway; Alzheimer disease pathway; ASSOCIATED WITH AURICULOCONDYLAR SYNDROME 2 (ortholog); Prostatic Neoplasms (ortholog); FOUND IN cytoplasm; dendrite (ortholog); nucleus (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil
Type: protein-coding
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4; Beta4aa; phosphoinositide phospholipase C; phosphoinositide phospholipase C-beta-4; Phospholipase C (BETA4); Phospholipase C beta4; phospholipase C-beta-4; PLC-beta-4; RATBETA4AA
Allele / Splice: Plcb4_v1   Plcb4_v2  
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.03128,601,185 - 128,971,720+NCBI
Rat Cytogenetic Map3q36 NCBI
RGSC Genome Assembly v5.03135,089,551 - 135,459,248+NCBI
RGSC Genome Assembly v3.43123,706,313 - 124,077,381+NCBI
Rat Celera Assembly3121,694,557 - 122,062,160+NCBI
Genome Assembly 3.13123,611,885 - 123,982,941+NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Plcb4
Entrez Gene
Ensembl Gene
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Vista + UCSC

RGD Object Information
RGD ID: 3345
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2015-05-12
Status: ACTIVE