Gene: Pdha1 (pyruvate dehydrogenase (lipoamide) alpha 1) Rattus norvegicus
Symbol: Pdha1
Name: pyruvate dehydrogenase (lipoamide) alpha 1
Description: ENCODES a protein that exhibits pyruvate dehydrogenase (acetyl-transferring) activity; pyruvate dehydrogenase (NAD+) activity (ortholog); pyruvate dehydrogenase activity (ortholog); INVOLVED IN acetyl-CoA biosynthetic process from pyruvate; mitochondrial acetyl-CoA biosynthetic process from pyruvate (ortholog); tricarboxylic acid cycle (ortholog); PARTICIPATES IN pyruvate metabolic pathway; butanoate metabolic pathway; citric acid cycle pathway; ASSOCIATED WITH Abnormalities, Multiple (ortholog); Leigh Syndrome, X-Linked (ortholog); Pyruvate Dehydrogenase Complex Deficiency Disease (ortholog); FOUND IN mitochondrion; pyruvate dehydrogenase complex; myelin sheath (ortholog); INTERACTS WITH ammonium chloride; bezafibrate; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC114215; MGC94854; PDHE1-A type I; pyruvate dehydrogenase E1 alpha 1; pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; pyruvate dehydrogenase E1alpha subunit
Related Pseudogenes: Pdha1l1  
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.0X37,329,779 - 37,343,410+NCBI
Rat Cytogenetic MapXq21 NCBI
RGSC Genome Assembly v5.0X37,640,725 - 37,654,356+NCBI
RGSC Genome Assembly v3.4X55,899,491 - 55,913,319+NCBI
Rat Celera AssemblyX35,373,056 - 35,386,884+NCBI
Genome Assembly 3.1X55,952,967 - 55,966,789+NCBI

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Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

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Nomenclature History
RGD Curation Notes
More on Pdha1
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RGD Object Information
RGD ID: 3286
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2015-10-06
Status: ACTIVE