Gene: Pdha1 (pyruvate dehydrogenase (lipoamide) alpha 1) Rattus norvegicus
Symbol: Pdha1
Name: pyruvate dehydrogenase (lipoamide) alpha 1
Description: ENCODES a protein that exhibits pyruvate dehydrogenase (acetyl-transferring) activity; pyruvate dehydrogenase activity (ortholog); INVOLVED IN acetyl-CoA biosynthetic process from pyruvate; oxidation-reduction process (ortholog); tricarboxylic acid cycle (ortholog); PARTICIPATES IN pyruvate metabolic pathway; butanoate metabolic pathway; citric acid cycle pathway; ASSOCIATED WITH Leigh Syndrome, X-Linked (ortholog); Pyruvate Dehydrogenase Complex Deficiency Disease (ortholog); FOUND IN mitochondrion; pyruvate dehydrogenase complex; nucleus (ortholog); INTERACTS WITH ammonium chloride; bezafibrate; diuron
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC114215; MGC94854; PDHE1-A type I; pyruvate dehydrogenase E1 alpha 1; pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; pyruvate dehydrogenase E1alpha subunit
Orthologs:
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic MapXq21 NCBI
RGSC Genome Assembly v5.0X37,640,725 - 37,654,356+NCBI
RGSC Genome Assembly v3.4X55,899,491 - 55,913,319+NCBI
Rat Celera AssemblyX35,373,056 - 35,386,884+NCBI
Genome Assembly 3.1X55,952,967 - 55,966,789+NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pdha1
Entrez Gene
Ensembl Gene
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NCBI Map Viewer
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Vista + UCSC

RGD Object Information
RGD ID: 3286
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2014-04-08
Status: ACTIVE