Gene: Pdha1 (pyruvate dehydrogenase (lipoamide) alpha 1) Rattus norvegicus
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Symbol: Pdha1
Name: pyruvate dehydrogenase (lipoamide) alpha 1
Description: ENCODES a protein that exhibits pyruvate dehydrogenase (acetyl-transferring) activity; pyruvate dehydrogenase (NAD+) activity (ortholog); pyruvate dehydrogenase activity (ortholog); INVOLVED IN acetyl-CoA biosynthetic process from pyruvate; mitochondrial acetyl-CoA biosynthetic process from pyruvate (ortholog); tricarboxylic acid cycle (ortholog); PARTICIPATES IN citric acid cycle pathway; fumaric aciduria disease pathway; Leigh syndrome pathway; ASSOCIATED WITH Abnormalities, Multiple (ortholog); Acidosis, Lactic (ortholog); Disease Progression (ortholog); FOUND IN mitochondrion; pyruvate dehydrogenase complex; myelin sheath (ortholog); INTERACTS WITH 17beta-estradiol; ammonium chloride; bezafibrate
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC114215; MGC94854; PDHE1-A type I; pyruvate dehydrogenase E1 alpha 1; pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; pyruvate dehydrogenase E1alpha subunit
Orthologs:
Related Pseudogenes: Pdha1l1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X37,329,779 - 37,343,410 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0X37,640,725 - 37,654,356 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4X55,899,491 - 55,913,319 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X55,952,967 - 55,966,789 (+)NCBI
CeleraX35,373,056 - 35,386,884 (+)NCBI
Cytogenetic MapXq14NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pdha1
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 3286
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-11-18
Status: ACTIVE