Gene: Pdha1 (pyruvate dehydrogenase E1 alpha 1 subunit) Rattus norvegicus
Analyze
Symbol: Pdha1
Name: pyruvate dehydrogenase E1 alpha 1 subunit
Description: ENCODES a protein that exhibits pyruvate dehydrogenase (acetyl-transferring) activity; pyruvate dehydrogenase (NAD+) activity (ortholog); pyruvate dehydrogenase activity (ortholog); INVOLVED IN acetyl-CoA biosynthetic process from pyruvate; mitochondrial acetyl-CoA biosynthetic process from pyruvate (ortholog); tricarboxylic acid cycle (ortholog); PARTICIPATES IN citric acid cycle pathway; fumaric aciduria disease pathway; Leigh syndrome pathway; ASSOCIATED WITH pyruvate decarboxylase deficiency; Pyruvate Dehydrogenase Complex Deficiency Disease; Abnormalities, Multiple (ortholog); FOUND IN mitochondrion; pyruvate dehydrogenase complex; myelin sheath (ortholog); INTERACTS WITH 17beta-estradiol; 3-chloropropane-1,2-diol; ammonium chloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC114215; MGC94854; PDHE1-A type I; pyruvate dehydrogenase (lipoamide) alpha 1; pyruvate dehydrogenase alpha 1; pyruvate dehydrogenase E1 alpha 1; pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; pyruvate dehydrogenase E1alpha subunit
Orthologs:
Homo sapiens (human) : PDHA1 (pyruvate dehydrogenase E1 alpha 1 subunit)  HGNC  AGR
Mus musculus (house mouse) : Pdha1 (pyruvate dehydrogenase E1 alpha 1)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Pdha1 (pyruvate dehydrogenase E1 alpha 1 subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : PDHA1 (pyruvate dehydrogenase E1 alpha 1 subunit)
Canis lupus familiaris (dog) : PDHA1 (pyruvate dehydrogenase E1 alpha 1 subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdha1 (pyruvate dehydrogenase E1 alpha 1 subunit)
more info ...
Related Pseudogenes: Pdha1l1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X37,329,779 - 37,343,410 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0X37,640,725 - 37,654,356 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4X55,899,491 - 55,913,319 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X55,952,967 - 55,966,789 (+)NCBI
CeleraX35,373,056 - 35,386,884 (+)NCBI
Cytogenetic MapXq14NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pdha1
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 3286
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE