Gene: Pdha1 (pyruvate dehydrogenase (lipoamide) alpha 1) Rattus norvegicus
Symbol: Pdha1
Name: pyruvate dehydrogenase (lipoamide) alpha 1
Description: ENCODES a protein that exhibits pyruvate dehydrogenase (acetyl-transferring) activity; pyruvate dehydrogenase (NAD+) activity (ortholog); pyruvate dehydrogenase activity (ortholog); INVOLVED IN acetyl-CoA biosynthetic process from pyruvate; mitochondrial acetyl-CoA biosynthetic process from pyruvate (ortholog); oxidation-reduction process (ortholog); PARTICIPATES IN pyruvate metabolic pathway; butanoate metabolic pathway; citric acid cycle pathway; ASSOCIATED WITH Leigh Syndrome, X-Linked (ortholog); Pyruvate Dehydrogenase Complex Deficiency Disease (ortholog); Pyruvate Dehydrogenase E1 Alpha Deficiency (ortholog); FOUND IN mitochondrion; pyruvate dehydrogenase complex; myelin sheath (ortholog); INTERACTS WITH ammonium chloride; bezafibrate; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC114215; MGC94854; PDHE1-A type I; pyruvate dehydrogenase E1 alpha 1; pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; pyruvate dehydrogenase E1alpha subunit
Orthologs:
Related Pseudogenes: Pdha1l1  
Latest Assembly: RGSC Genome Assembly v5.0
Position:
MapChrPositionStrandSource
RGSC Genome Assembly v6.0X37,329,779 - 37,343,410+NCBI
Rat Cytogenetic MapXq21 NCBI
RGSC Genome Assembly v5.0X37,640,725 - 37,654,356+NCBI
RGSC Genome Assembly v3.4X55,899,491 - 55,913,319+NCBI
Rat Celera AssemblyX35,373,056 - 35,386,884+NCBI
Genome Assembly 3.1X55,952,967 - 55,966,789+NCBI
Model

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Disease Annotations
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References - curated
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Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
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RGD Object Information
RGD ID: 3286
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2015-07-07
Status: ACTIVE