Gene: Pdha1 (pyruvate dehydrogenase alpha 1) Rattus norvegicus
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Symbol: Pdha1
Name: pyruvate dehydrogenase alpha 1
Description: ENCODES a protein that exhibits pyruvate dehydrogenase (acetyl-transferring) activity; pyruvate dehydrogenase (NAD+) activity (ortholog); pyruvate dehydrogenase activity (ortholog); INVOLVED IN acetyl-CoA biosynthetic process from pyruvate; mitochondrial acetyl-CoA biosynthetic process from pyruvate (ortholog); tricarboxylic acid cycle (ortholog); PARTICIPATES IN citric acid cycle pathway; fumaric aciduria disease pathway; Leigh syndrome pathway; ASSOCIATED WITH pyruvate decarboxylase deficiency; Pyruvate Dehydrogenase Complex Deficiency Disease; Abnormalities, Multiple (ortholog); FOUND IN mitochondrion; pyruvate dehydrogenase complex; myelin sheath (ortholog); INTERACTS WITH 17beta-estradiol; 3-chloropropane-1,2-diol; ammonium chloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC114215; MGC94854; PDHE1-A type I; pyruvate dehydrogenase (lipoamide) alpha 1; pyruvate dehydrogenase E1 alpha 1; pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; pyruvate dehydrogenase E1alpha subunit
Orthologs:
Homo sapiens (human) : PDHA1 (pyruvate dehydrogenase alpha 1)  HGNC
Mus musculus (house mouse) : Pdha1 (pyruvate dehydrogenase E1 alpha 1)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Pdha1 (pyruvate dehydrogenase alpha 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PDHA1 (pyruvate dehydrogenase alpha 1)
Canis lupus familiaris (dog) : PDHA1 (pyruvate dehydrogenase alpha 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdha1 (pyruvate dehydrogenase alpha 1)
more info ...
Related Pseudogenes: Pdha1l1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X37,329,779 - 37,343,410 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0X37,640,725 - 37,654,356 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4X55,899,491 - 55,913,319 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X55,952,967 - 55,966,789 (+)NCBI
CeleraX35,373,056 - 35,386,884 (+)NCBI
Cytogenetic MapXq14NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pdha1
NCBI Gene
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RGD Object Information
RGD ID: 3286
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-07-04
Status: ACTIVE