Gene: Pdha1 (pyruvate dehydrogenase (lipoamide) alpha 1) Rattus norvegicus
Symbol: Pdha1
Name: pyruvate dehydrogenase (lipoamide) alpha 1
Description: ENCODES a protein that exhibits pyruvate dehydrogenase (acetyl-transferring) activity; pyruvate dehydrogenase (NAD+) activity (ortholog); pyruvate dehydrogenase activity (ortholog); INVOLVED IN acetyl-CoA biosynthetic process from pyruvate; mitochondrial acetyl-CoA biosynthetic process from pyruvate (ortholog); tricarboxylic acid cycle (ortholog); PARTICIPATES IN citric acid cycle pathway; fumaric aciduria disease pathway; Leigh syndrome pathway; ASSOCIATED WITH Abnormalities, Multiple (ortholog); Leigh Syndrome, X-Linked (ortholog); Pyruvate Dehydrogenase Complex Deficiency Disease (ortholog); FOUND IN mitochondrion; pyruvate dehydrogenase complex; myelin sheath (ortholog); INTERACTS WITH ammonium chloride; bezafibrate; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC114215; MGC94854; PDHE1-A type I; pyruvate dehydrogenase E1 alpha 1; pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; pyruvate dehydrogenase E1alpha subunit
Related Pseudogenes: Pdha1l1  
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.0X37,329,779 - 37,343,410+NCBI
Rat Cytogenetic MapXq21 NCBI
RGSC Genome Assembly v5.0X37,640,725 - 37,654,356+NCBI
RGSC Genome Assembly v3.4X55,899,491 - 55,913,319+NCBI
Rat Celera AssemblyX35,373,056 - 35,386,884+NCBI
Genome Assembly 3.1X55,952,967 - 55,966,789+NCBI

Launch Genome Browser (GBrowse)     Launch JBrowse

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Pdha1
Entrez Gene
Ensembl Gene
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 3286
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-02-02
Status: ACTIVE