Mog (myelin oligodendrocyte glycoprotein) - Rat Genome Database

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Gene: Mog (myelin oligodendrocyte glycoprotein) Rattus norvegicus
Analyze
Symbol: Mog
Name: myelin oligodendrocyte glycoprotein
RGD ID: 3102
Description: Predicted to enable signaling receptor binding activity. Involved in response to folic acid and response to lipid. Located in cell surface. Used to study optic neuritis. Human ortholog(s) of this gene implicated in multiple sclerosis; narcolepsy; and optic neuritis. Orthologous to human MOG (myelin oligodendrocyte glycoprotein); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: dystonia 2, torsion (autosomal recessive); MGC105427; myelin-oligodendrocyte glycoprotein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8201,514,110 - 1,528,716 (+)NCBIGRCr8
mRatBN7.2201,513,137 - 1,523,473 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl201,513,239 - 1,523,474 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx201,566,600 - 1,576,839 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0201,570,095 - 1,580,335 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0201,511,656 - 1,521,982 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0202,003,871 - 2,014,284 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl202,004,052 - 2,014,286 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0204,044,603 - 4,054,909 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4201,601,731 - 1,611,963 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1201,601,730 - 1,611,964 (+)NCBI
Celera202,221,796 - 2,232,018 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Purification and partial structural and functional characterization of mouse myelin/oligodendrocyte glycoprotein. Amiguet P, etal., J Neurochem 1992 May;58(5):1676-82.
2. Comparative immunohistochemical study of C1G5F2 antigen and myelin/oligodendrocyte glycoprotein (MOG) expression in brain of several animal species. Birling MC and Nussbaum JL, Neurosci Lett. 1995 Feb 6;185(1):9-12.
3. Myelin/oligodendrocyte glycoprotein is a unique member of the immunoglobulin superfamily. Gardinier MV, etal., J Neurosci Res 1992 Sep;33(1):177-87.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Calcium influx and calpain activation mediate preclinical retinal neurodegeneration in autoimmune optic neuritis. Hoffmann DB, etal., J Neuropathol Exp Neurol. 2013 Aug;72(8):745-57. doi: 10.1097/NEN.0b013e31829c7370.
7. Relationship between NMO-antibody and anti-MOG antibody in optic neuritis. Kezuka T, etal., J Neuroophthalmol. 2012 Jun;32(2):107-10. doi: 10.1097/WNO.0b013e31823c9b6c.
8. Myelin glycosphingolipid/cholesterol-enriched microdomains selectively sequester the non-compact myelin proteins CNP and MOG. Kim T and Pfeiffer SE, J Neurocytol. 1999 Apr-May;28(4-5):281-93.
9. Effects of dietary folic acid on the expression of myelin basic protein in the brain and spinal cord of pregnant and lactating rats. Lee JH, etal., Ann Nutr Metab. 2010;56(2):83-90. doi: 10.1159/000275945. Epub 2010 Jan 19.
10. Oligodendrocyte progenitor cells in the adult rat CNS express myelin oligodendrocyte glycoprotein (MOG). Li G, etal., Brain Pathol 2002 Oct;12(4):463-71.
11. The magnitude and encephalogenic potential of autoimmune response to MOG is enhanced in MOG deficient mice. Linares D, etal., J Autoimmun. 2003 Dec;21(4):339-51.
12. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
14. Genetic variation in myelin oligodendrocyte glycoprotein expression and susceptibility to experimental autoimmune encephalomyelitis. Pagany M, etal., J Neuroimmunol. 2003 Jun;139(1-2):1-8.
15. Myelin/oligodendrocyte glycoprotein is a member of a subset of the immunoglobulin superfamily encoded within the major histocompatibility complex. Pham-Dinh D, etal., Proc Natl Acad Sci U S A 1993 Sep 1;90(17):7990-4.
16. GOA pipeline RGD automated data pipeline
17. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
18. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
19. Comprehensive gene review and curation RGD comprehensive gene curation
20. Accelerated myelinogenesis by dietary lipids in rat brain. Salvati S, etal., J Neurochem. 1996 Oct;67(4):1744-50.
21. Myelin oligodendrocyte glycoprotein induces experimental autoimmune encephalomyelitis in the "resistant" Brown Norway rat: disease susceptibility is determined by MHC and MHC-linked effects on the B cell response. Stefferl A, etal., J Immunol. 1999 Jul 1;163(1):40-9.
22. Biochemical and morphologic evidence of the interaction of oligodendrocyte membrane rafts with actin filaments. Taguchi K, etal., J Neurosci Res. 2005 Jul 15;81(2):218-25.
23. Age-related decline of myelin proteins is highly correlated with activation of astrocytes and microglia in the rat CNS. Xie F, etal., Int J Mol Med. 2013 Sep 11. doi: 10.3892/ijmm.2013.1486.
24. Downregulation of microRNA-199a-5p alleviated lidocaine-induced sensory dysfunction and spinal cord myelin lesions in a rat model. Zhang Z, etal., Toxicol Lett. 2021 Jan 1;336:1-10. doi: 10.1016/j.toxlet.2020.11.001. Epub 2020 Nov 6.
25. Identification of a pathogenic antibody response to native myelin oligodendrocyte glycoprotein in multiple sclerosis. Zhou D, etal., Proc Natl Acad Sci U S A. 2006 Dec 12;103(50):19057-62. Epub 2006 Dec 1.
Additional References at PubMed
PMID:9210466   PMID:12477932   PMID:12817031   PMID:12874380   PMID:12935913   PMID:15968633   PMID:16314284   PMID:16773652   PMID:16905253   PMID:17630211   PMID:17634366   PMID:18203139  
PMID:18204890   PMID:18501024   PMID:19580419   PMID:20844138   PMID:21643729   PMID:24157309   PMID:24552747   PMID:26347141   PMID:27483998   PMID:29476059  


Genomics

Comparative Map Data
Mog
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8201,514,110 - 1,528,716 (+)NCBIGRCr8
mRatBN7.2201,513,137 - 1,523,473 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl201,513,239 - 1,523,474 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx201,566,600 - 1,576,839 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0201,570,095 - 1,580,335 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0201,511,656 - 1,521,982 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0202,003,871 - 2,014,284 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl202,004,052 - 2,014,286 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0204,044,603 - 4,054,909 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4201,601,731 - 1,611,963 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1201,601,730 - 1,611,964 (+)NCBI
Celera202,221,796 - 2,232,018 (+)NCBICelera
Cytogenetic Map20p12NCBI
MOG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38629,657,092 - 29,672,365 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl629,657,002 - 29,672,372 (+)EnsemblGRCh38hg38GRCh38
GRCh37629,624,869 - 29,640,142 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36629,732,788 - 29,748,128 (+)NCBINCBI36Build 36hg18NCBI36
Build 34629,732,787 - 29,748,126NCBI
Celera631,230,837 - 31,246,226 (+)NCBICelera
Cytogenetic Map6p22.1NCBI
HuRef629,431,836 - 29,447,189 (+)NCBIHuRef
CHM1_1629,626,856 - 29,642,241 (+)NCBICHM1_1
T2T-CHM13v2.0629,531,788 - 29,547,063 (+)NCBIT2T-CHM13v2.0
Mog
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391737,321,632 - 37,334,290 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1737,321,635 - 37,334,290 (-)EnsemblGRCm39 Ensembl
GRCm381737,010,740 - 37,023,398 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1737,010,743 - 37,023,398 (-)EnsemblGRCm38mm10GRCm38
MGSCv371737,147,685 - 37,160,343 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361736,619,557 - 36,631,252 (-)NCBIMGSCv36mm8
Celera1740,434,333 - 40,446,808 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1719.16NCBI
Mog
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955583136,077 - 150,649 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955583136,077 - 150,597 (+)NCBIChiLan1.0ChiLan1.0
MOG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2544,276,484 - 44,291,676 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1640,239,830 - 40,255,018 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0629,461,174 - 29,476,362 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1630,119,599 - 30,134,152 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl630,119,599 - 30,134,152 (+)Ensemblpanpan1.1panPan2
MOG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13526,256,311 - 26,267,357 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3526,256,489 - 26,266,832 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.03526,564,777 - 26,575,774 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3526,564,900 - 26,577,576 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13526,219,498 - 26,230,464 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03526,280,177 - 26,291,397 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03527,750,470 - 27,761,462 (+)NCBIUU_Cfam_GSD_1.0
Mog
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494632,480,068 - 32,521,821 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367231,070,117 - 1,081,323 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367231,070,071 - 1,112,487 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MOG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl722,595,510 - 22,610,817 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1722,595,565 - 22,606,137 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2725,181,816 - 25,192,432 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MOG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11742,947,174 - 42,963,046 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1742,947,279 - 42,962,159 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604429,186,569 - 29,201,041 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mog
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475425,397,144 - 25,411,319 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475425,397,191 - 25,412,123 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mog
103 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:106
Count of miRNA genes:82
Interacting mature miRNAs:97
Transcripts:ENSRNOT00000001008
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724519Bp144Blood pressure QTL 1440.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2013624629Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat

Markers in Region
RH144164  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2201,517,629 - 1,517,785 (+)MAPPERmRatBN7.2
Rnor_6.0202,008,442 - 2,008,597NCBIRnor6.0
Rnor_5.0204,049,067 - 4,049,222UniSTSRnor5.0
RGSC_v3.4201,606,121 - 1,606,276UniSTSRGSC3.4
Celera202,226,186 - 2,226,341UniSTS
RH 3.4 Map2022.5UniSTS
Cytogenetic Map20p12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 25 2 4
Low 3 8 26 10 14 10 2 2 24 11 18 7 2
Below cutoff 23 7 7 5 7 6 9 23 12 20 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_022668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006255867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC108572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH011151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH011152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH011153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC087717 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX883052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L21995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M99485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000001008   ⟹   ENSRNOP00000001008
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl201,513,239 - 1,523,474 (+)Ensembl
Rnor_6.0 Ensembl202,004,052 - 2,014,286 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000110773   ⟹   ENSRNOP00000087198
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl201,515,052 - 1,522,000 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000118690   ⟹   ENSRNOP00000078844
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl201,513,239 - 1,523,474 (+)Ensembl
RefSeq Acc Id: NM_022668   ⟹   NP_073159
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8201,518,484 - 1,528,714 (+)NCBI
mRatBN7.2201,513,239 - 1,523,473 (+)NCBI
Rnor_6.0202,004,052 - 2,014,284 (+)NCBI
Rnor_5.0204,044,603 - 4,054,909 (+)NCBI
RGSC_v3.4201,601,731 - 1,611,963 (+)RGD
Celera202,221,796 - 2,232,018 (+)RGD
Sequence:
RefSeq Acc Id: XM_006255867   ⟹   XP_006255929
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8201,514,110 - 1,528,716 (+)NCBI
mRatBN7.2201,513,137 - 1,523,237 (+)NCBI
Rnor_6.0202,003,938 - 2,014,283 (+)NCBI
Rnor_5.0204,044,603 - 4,054,909 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039098414   ⟹   XP_038954342
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8201,514,110 - 1,528,716 (+)NCBI
mRatBN7.2201,513,434 - 1,523,237 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_073159   ⟸   NM_022668
- Peptide Label: precursor
- UniProtKB: Q63345 (UniProtKB/Swiss-Prot),   Q6MFX9 (UniProtKB/TrEMBL),   F6PTF1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255929   ⟸   XM_006255867
- Peptide Label: isoform X1
- UniProtKB: Q63345 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000001008   ⟸   ENSRNOT00000001008
RefSeq Acc Id: XP_038954342   ⟸   XM_039098414
- Peptide Label: isoform X2
RefSeq Acc Id: ENSRNOP00000078844   ⟸   ENSRNOT00000118690
RefSeq Acc Id: ENSRNOP00000087198   ⟸   ENSRNOT00000110773
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63345-F1-model_v2 AlphaFold Q63345 1-245 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701269
Promoter ID:EPDNEW_R11793
Type:single initiation site
Name:Mog_1
Description:myelin oligodendrocyte glycoprotein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0202,004,080 - 2,004,140EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3102 AgrOrtholog
BioCyc Gene G2FUF-4987 BioCyc
Ensembl Genes ENSRNOG00000000775 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00055009183 UniProtKB/Swiss-Prot
  ENSRNOG00060003357 UniProtKB/Swiss-Prot
  ENSRNOG00065027553 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000001008 ENTREZGENE
  ENSRNOT00000001008.4 UniProtKB/TrEMBL
  ENSRNOT00000110773.1 UniProtKB/TrEMBL
  ENSRNOT00000118690.1 UniProtKB/TrEMBL
  ENSRNOT00055015553 UniProtKB/Swiss-Prot
  ENSRNOT00060005530 UniProtKB/Swiss-Prot
  ENSRNOT00065047565 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7317044 IMAGE-MGC_LOAD
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myelin-oligodendrocyte_glycop UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24558 UniProtKB/TrEMBL
MGC_CLONE MGC:105427 IMAGE-MGC_LOAD
NCBI Gene 24558 ENTREZGENE
PANTHER BUTYROPHILIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MYELIN-OLIGODENDROCYTE GLYCOPROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mog PhenoGen
PIRSF MOG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000775 RatGTEx
  ENSRNOG00055009183 RatGTEx
  ENSRNOG00060003357 RatGTEx
  ENSRNOG00065027553 RatGTEx
SMART IGv UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZLK9_RAT UniProtKB/TrEMBL
  A0A8I6A3S4_RAT UniProtKB/TrEMBL
  A6KR63_RAT UniProtKB/TrEMBL
  F6PTF1 ENTREZGENE, UniProtKB/TrEMBL
  MOG_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q6MFX9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Mog  Myelin oligodendrocyte glycoprotein      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localizes on the surface of myelin and oligodendrocyte cytoplasmic membranes 727550
gene_mapping found within the rat major histocompatibility RT1 complex 1300431