Annotation (Toggle Detail/Summary View) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene-Chemical Interaction AnnotationsGene-Chemical Interaction Annotations
Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of MAS1 mRNA | CTD | PMID:16483693 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of MAS1 mRNA | CTD | PMID:21839799 | choline | multiple interactions | ISO | RGD:731462 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of MAS1 mRNA | CTD | PMID:20938992 | clozapine | decreases expression | EXP | | 6480464 | Clozapine results in decreased expression of MAS1 mRNA | CTD | PMID:16715494 | diazoxide | decreases expression | EXP | | 6480464 | Isoproterenol results in decreased expression of MAS1 protein | CTD | PMID:20409916 | dimethylarsinic acid | decreases expression | ISO | RGD:731462 | 6480464 | Cacodylic Acid results in decreased expression of MAS1 mRNA | CTD | PMID:22246474 | folic acid | multiple interactions | ISO | RGD:731462 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of MAS1 mRNA | CTD | PMID:20938992 | haloperidol | decreases expression | EXP | | 6480464 | Haloperidol results in decreased expression of MAS1 mRNA | CTD | PMID:16715494 | hydralazine | multiple interactions | ISO | RGD:731461 | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of MAS1 mRNA | CTD | PMID:17183730 | isoprenaline | decreases expression | EXP | | 6480464 | Isoproterenol results in decreased expression of MAS1 protein | CTD | PMID:20409916 | ketamine | decreases expression | EXP | | 6480464 | Ketamine results in decreased expression of MAS1 mRNA | CTD | PMID:20080153 | L-methionine | multiple interactions | ISO | RGD:731462 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of MAS1 mRNA | CTD | PMID:20938992 | paracetamol | affects expression | ISO | RGD:731462 | 6480464 | Acetaminophen affects the expression of MAS1 mRNA | CTD | PMID:17562736 | paraquat | affects expression | EXP | | 6480464 | Paraquat affects the expression of MAS1 mRNA | CTD | PMID:15206577 | pirinixic acid | decreases expression | ISO | RGD:731462 | 6480464 | pirinixic acid results in decreased expression of MAS1 mRNA | CTD | PMID:20813756 | streptozocin | decreases expression | ISO | RGD:731462 | 6480464 | Streptozocin results in decreased expression of MAS1 protein | CTD | PMID:21381899 | streptozocin | multiple interactions | ISO | RGD:731462 | 6480464 | telmisartan inhibits the reaction [Streptozocin results in decreased expression of MAS1 protein] | CTD | PMID:21381899 | telmisartan | multiple interactions | ISO | RGD:731462 | 6480464 | telmisartan inhibits the reaction [Streptozocin results in decreased expression of MAS1 protein] | CTD | PMID:21381899 | valproic acid | affects expression | ISO | RGD:731462 | 6480464 | Valproic Acid affects the expression of MAS1 mRNA | CTD | PMID:17292431 | valproic acid | multiple interactions | ISO | RGD:731461 | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of MAS1 mRNA | CTD | PMID:17183730 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology AnnotationsMolecular Pathway Annotations| External Database Links | |
| KEGG Pathway | Neuroactive ligand-receptor interaction |
| Renin-angiotensin system | |
Disease Annotations
|
|
Gene-Chemical Interaction Annotations
|
|
|
Gene Ontology Annotations
|
|
|
|
Molecular Pathway Annotations
|
| External Database Links | |
| KEGG Pathway | Neuroactive ligand-receptor interaction |
| Renin-angiotensin system | |
References - curated| 1. |
da Silva AQ, etal., Brain Res. 2011 Jan 12;1368:231-8. Epub 2010 Oct 30. |
| 2. |
Filho AG, etal., Exp Physiol. 2008 May;93(5):589-98. |
| 3. |
GOA data from the GO Consortium |
| 4. |
Huang ML, etal., Clin Exp Pharmacol Physiol. 2009 Sep 28. |
| 5. |
Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7 |
| 6. |
Leal MC, etal., J Anat. 2009 May;214(5):736-43. |
| 7. |
Martin KA, etal., Brain Res Dev Brain Res. 1992 Jul 24;68(1):75-82. |
| 8. |
Metzger R, etal., FEBS Lett. 1995 Jan 2;357(1):27-32. |
| 9. |
MGD data from the GO Consortium |
| 10. |
Moon JY, etal., Nephron Exp Nephrol. 2008;110(1):e8-e16. Epub 2008 Aug 4. |
| 11. |
NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 12. |
Pereira VM, etal., Reprod Sci. 2009 Aug 24. |
| 13. |
Pipeline to import KEGG annotations from KEGG into RGD Pathway Ontology |
| 14. |
Reudelhuber TL Curr Opin Nephrol Hypertens. 2005 Mar;14(2):155-9. |
| 15. |
Reudelhuber TL Hypertension. 2006 May;47(5):811-5. Epub 2006 Mar 6. |
| 16. |
RGD automated data pipeline |
| 17. |
RGD automated import pipeline for gene-chemical interactions |
| 18. |
RGD comprehensive gene curation |
| 19. |
Strausberg RL, etal., Proc Natl Acad Sci U S A 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11. |
| 20. |
Tallant EA, etal., Am J Physiol Heart Circ Physiol. 2005 Oct;289(4):H1560-6. Epub 2005 Jun 10. |
| 21. |
Tentative Sequence Data IDs. TIGR Gene Index, Rat Data |
| 22. |
Velkoska E, etal., Clin Sci (Lond). 2009 Aug 21. |
| 23. |
Walther T, etal., J Biol Chem 1998 May 8;273(19):11867-73. |
| 24. |
Wolf G and Neilson EG, Am J Physiol. 1992 Nov;263(5 Pt 2):F931-8. |
| 25. |
Young D, etal., Proc Natl Acad Sci U S A 1988 Jul;85(14):5339-42. |
| 26. |
Zylka MJ, etal., Proc Natl Acad Sci U S A 2003 Aug 19;100(17):10043-8. Epub 2003 Aug 8. |
References - uncurated| PubMed | 15489334 |
| 16087780 | |
| 17496218 | |
| 18026570 | |
| 21436210 | |
| 22003054 | |
| 22504011 | |
| 22561449 | |
| 22561450 | |
| 22775972 | |
| 22811473 |
RGD Disease Portals| Mas1 has been annotated in the following RGD Disease Portals. |
|||||||
 |
| ||||||
 |
| ||||||
 |
| ||||||
 |
| ||||||
 |
| ||||||
 |
| ||||||
 |
| ||||||
Comparative Map Data| Mas1 (Rattus norvegicus) |
|
|||||||||||||||||||||||||||||||||||
| MAS1 (Homo sapiens) |
|
|||||||||||||||||||||||||||||||||||
| Mas1 (Mus musculus) |
|
Position Markers| BB276039 |
|
||||||||||||||||||||||||||||||
| BF386436 |
|
||||||||||||||||||||||||||||||
| RH94551 |
|
||||||||||||||||||||||||||||||
| BF414744 |
|
QTLs in Region (RGSC Genome Assembly v3.4)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
Nucleotide Sequences| Nucleotide RefSeqs | NM_012757 | (Get FASTA) | Search GEO for Microarray Profiles |
| GenBank Nucleotide | AABR06002299 | (Get FASTA) | Search GEO for Microarray Profiles |
| AABR06002300 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01002920 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01002921 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01002922 | (Get FASTA) | Search GEO for Microarray Profiles | |
| BC078884 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CH474059 | (Get FASTA) | Search GEO for Microarray Profiles | |
| J03823 | (Get FASTA) | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | NM_012757 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Protein Acc Id: | NP_036889 | ||||||||||||||||||||
| Position: |
|
Protein Sequences| Protein RefSeqs | NP_036889 | (Get FASTA) |
| GenBank Protein | AAA41573 | (Get FASTA) |
| AAH78884 | (Get FASTA) | |
| EDL83047 | (Get FASTA) | |
| EDL83048 | (Get FASTA) | |
| P12526 | (Get FASTA) |
Strain Sequence Variants
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSRNOG00000014971 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Protein | ENSRNOP00000020100 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Transcript | ENSRNOT00000020100 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Entrez Gene | 25153 | ENTREZGENE |
| Germonline | ENSRNOG00000014971 | UniProtKB/Swiss-Prot |
| HomoloGene Group ID | 1782 | ENTREZGENE |
| IMAGE_CLONE | IMAGE:7131760 | IMAGE-MGC_LOAD |
| InterPro | 7TM_GPCR_Rhodpsn | UniProtKB/Swiss-Prot |
| GPCR_Rhodpsn_supfam | UniProtKB/Swiss-Prot | |
| Mas_TM | UniProtKB/Swiss-Prot | |
| MRGPCRFAMILY | UniProtKB/Swiss-Prot | |
| IPI | IPI00198560 | UniProtKB/Swiss-Prot |
| KEGG Report | rno:25153 | ENTREZGENE, UniProtKB/Swiss-Prot |
| MGC_CLONE | MGC:93580 | IMAGE-MGC_LOAD |
| PANTHER | PTHR11334 | UniProtKB/Swiss-Prot |
| PTHR11334:SF4 | UniProtKB/Swiss-Prot | |
| Pfam | 7tm_1 | UniProtKB/Swiss-Prot |
| PharmGKB | MAS1 | RGD |
| PRINTS | GPCRRHODOPSN | UniProtKB/Swiss-Prot |
| MASONCOGENE | UniProtKB/Swiss-Prot | |
| PROSITE | G_PROTEIN_RECEP_F1_1 | UniProtKB/Swiss-Prot |
| G_PROTEIN_RECEP_F1_2 | UniProtKB/Swiss-Prot | |
| TIGR | TC235714 | |
| UniGene | Rn.21943 | ENTREZGENE |
| UniProt | MAS_RAT | UniProtKB/Swiss-Prot |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2002-06-10 | Mas1 | MAS1 oncogene | Symbol and Name status set to approved | 1490 | APPROVED |
RGD Curation Notes| Note Type | Note | Reference |
|---|---|---|
| gene_expression | expressed in hippocampus and cerebral cortex | 728946 |
| More on Mas1 | |
|
Entrez Gene |
|
Ensembl Gene |
| Genome Browser |
|
NCBI Map Viewer |
|
Vista |
|
Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 3049 |
| Created: | 2000-05-25 |
| Species: | Rattus norvegicus |
| Last Modified: | 2013-04-16 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.