Gene: Fmr1 (fragile X mental retardation 1) Rattus norvegicus
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Symbol: Fmr1
Name: fragile X mental retardation 1
Description: ENCODES a protein that exhibits mRNA binding; protein domain specific binding; protein kinase binding; INVOLVED IN cellular response to monosodium glutamate; cellular response to potassium ion; detection of mechanical stimulus involved in sensory perception; ASSOCIATED WITH abnormal response to social novelty; abnormal social play behavior; enlarged testis; ASSOCIATED WITH Autism Spectrum Disorder; autism spectrum disorder; Brain Injuries; FOUND IN axon; axon terminus; axonal growth cone; INTERACTS WITH (S)-3,5-dihydroxyphenylglycine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: FMRP; fragile X mental retardation protein 1 homolog; fragile X mental retardation syndrome 1 homolog; fragile X mental retardation-1 protein; protein FMR-1; ragile X mental retardation protein; synaptic functional regulator FMR1
Orthologs:
Homo sapiens (human) : FMR1 (fragile X mental retardation 1)  HGNC  AGR
Mus musculus (house mouse) : Fmr1 (fragile X mental retardation syndrome 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Fmr1 (fragile X mental retardation 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FMR1 (fragile X mental retardation 1)
Canis lupus familiaris (dog) : FMR1 (fragile X mental retardation 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fmr1 (fragile X mental retardation 1)
more info ...
Allele / Splice: Fmr1em2Mcwi   Fmr1em4Mcwi   Fmr1em1Sage  
Genetic Models: SD-Fmr1em1Sage LE-Fmr1em2Mcwi LE-Fmr1em4Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X154,684,924 - 154,722,369 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01150,408,220 - 150,445,658 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X154,756,031 - 154,793,782 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X154,829,463 - 154,867,215 (+)NCBI
Celera1134,092,390 - 134,130,141 (-)NCBICelera
Cytogenetic MapXq37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Fmr1
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2623
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE