Gene: Dcc (DCC netrin 1 receptor) Rattus norvegicus
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Symbol: Dcc
Name: DCC netrin 1 receptor
Description: ENCODES a protein that exhibits identical protein binding; netrin receptor activity; transcription coactivator activity; INVOLVED IN axon guidance; positive regulation of ERK1 and ERK2 cascade; positive regulation of neuron projection development; PARTICIPATES IN colorectal cancer pathway; ASSOCIATED WITH Neuritis, Autoimmune, Experimental; Reperfusion Injury; Spinal Cord Injuries; FOUND IN axon; growth cone membrane; membrane raft; INTERACTS WITH 6-propyl-2-thiouracil; androgen antagonist; bis(2-ethylhexyl) phthalate
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: colorectal tumor suppressor; Deleted in colcorectal cancer (rat homolog); deleted in colorectal carcinoma; netrin receptor DCC; putative colorectal tumor suppressor; tumor suppressor protein DCC
Orthologs:
Homo sapiens (human) : DCC (DCC netrin 1 receptor)  HGNC
Mus musculus (house mouse) : Dcc (deleted in colorectal carcinoma)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Dcc (DCC netrin 1 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : DCC (DCC netrin 1 receptor)
Canis lupus familiaris (dog) : DCC (DCC netrin 1 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dcc (DCC netrin 1 receptor)
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Allele / Splice: DccTn(sb-T2/Bart3)2.205Mcwi  
Genetic Models: F344-DccTn(sb-T2/Bart3)2.205Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01866,518,213 - 67,629,801 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01865,688,901 - 66,793,126 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41868,026,795 - 69,140,741 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11868,099,995 - 69,213,942 (-)NCBI
Celera1862,907,666 - 64,001,277 (-)NCBI
Cytogenetic Map18q12.1NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Dcc
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 2492
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-05-30
Status: ACTIVE