Gene: Chrne (cholinergic receptor, nicotinic, epsilon (muscle)) Rattus norvegicus
Symbol: Chrne
Name: cholinergic receptor, nicotinic, epsilon (muscle)
Description: ENCODES a protein that exhibits acetylcholine-activated cation-selective channel activity; INVOLVED IN cation transmembrane transport; cation transport; skeletal muscle contraction; PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; ASSOCIATED WITH Myasthenia, Familial Infantile, 1 (ortholog); MYASTHENIC SYNDROME, CONGENITAL, ASSOCIATED WITH ACETYLCHOLINE RECEPTOR DEFICIENCY (ortholog); Myasthenic Syndrome, Congenital, Fast-Channel (ortholog); FOUND IN acetylcholine-gated channel complex; postsynaptic membrane (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acetylcholine; ammonium chloride
Type: protein-coding
Also known as: acetylcholine receptor epsilon; acetylcholine receptor subunit epsilon; cholinergic receptor, nicotinic, epsilon; cholinergic receptor, nicotinic, epsilon polypeptide; epsilon-subunit; gene for acetylcholine receptor epsilon subunit
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.01057,238,960 - 57,247,632-NCBI
Rat Cytogenetic Map10q24 NCBI
RGSC Genome Assembly v5.01056,984,503 - 56,992,199-NCBI
RGSC Genome Assembly v3.41057,497,192 - 57,501,511-NCBI
Rat Celera Assembly1054,476,876 - 54,481,195-NCBI
Genome Assembly 3.11057,510,815 - 57,515,134-NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (RGSC Genome Assembly v5.0)


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Chrne
Entrez Gene
Ensembl Gene
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RGD Object Information
RGD ID: 2353
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2015-05-12
Status: ACTIVE