Mir301b (microRNA 301b) - Rat Genome Database

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Gene: Mir301b (microRNA 301b) Rattus norvegicus
Analyze
Symbol: Mir301b
Name: microRNA 301b
RGD ID: 2325503
Description: Predicted to enable mRNA base-pairing translational repressor activity. Predicted to be involved in lipoprotein transport; miRNA-mediated post-transcriptional gene silencing; and negative regulation of cholesterol efflux. Predicted to act upstream of or within cellular response to leukemia inhibitory factor and long-term synaptic potentiation. Orthologous to human MIR301B (microRNA 301b); INTERACTS WITH atrazine; cisplatin; Monobutylphthalate.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: microRNA mir-301b; rno-mir-301b
RGD Orthologs
Human
Mouse
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81197,384,033 - 97,384,110 (+)NCBIGRCr8
mRatBN7.21183,879,816 - 83,879,893 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1183,879,816 - 83,879,893 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1192,603,539 - 92,603,616 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01185,264,681 - 85,264,758 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01184,318,262 - 84,318,339 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01188,129,426 - 88,129,503 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1188,129,426 - 88,129,503 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01191,181,973 - 91,182,050 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1182,635,547 - 82,635,624 (+)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16381832   PMID:17604727   PMID:20403161   PMID:20439489   PMID:25858512   PMID:29733818  


Genomics

Comparative Map Data
Mir301b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81197,384,033 - 97,384,110 (+)NCBIGRCr8
mRatBN7.21183,879,816 - 83,879,893 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1183,879,816 - 83,879,893 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1192,603,539 - 92,603,616 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01185,264,681 - 85,264,758 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01184,318,262 - 84,318,339 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01188,129,426 - 88,129,503 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1188,129,426 - 88,129,503 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01191,181,973 - 91,182,050 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1182,635,547 - 82,635,624 (+)NCBICelera
Cytogenetic Map11q23NCBI
MIR301B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382221,652,981 - 21,653,058 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2221,652,981 - 21,653,058 (+)EnsemblGRCh38hg38GRCh38
GRCh372222,007,270 - 22,007,347 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362220,337,269 - 20,337,346 (+)NCBINCBI36Build 36hg18NCBI36
Celera225,824,810 - 5,824,887 (+)NCBICelera
Cytogenetic Map22q11.21NCBI
HuRef224,965,094 - 4,965,171 (+)NCBIHuRef
CHM1_12222,007,462 - 22,007,539 (+)NCBICHM1_1
T2T-CHM13v2.02222,066,472 - 22,066,549 (+)NCBIT2T-CHM13v2.0
Mir301b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391616,942,264 - 16,942,360 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1616,942,264 - 16,942,360 (-)EnsemblGRCm39 Ensembl
GRCm381617,124,400 - 17,124,496 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1617,124,400 - 17,124,496 (-)EnsemblGRCm38mm10GRCm38
MGSCv371617,124,493 - 17,124,589 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1617,697,194 - 17,697,290 (-)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1610.62NCBI
MIR301B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12630,924,103 - 30,924,178 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2630,924,103 - 30,924,178 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2630,881,301 - 30,881,376 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02632,329,837 - 32,329,912 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12630,379,140 - 30,379,215 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02630,002,840 - 30,002,915 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02631,092,810 - 31,092,885 (+)NCBIUU_Cfam_GSD_1.0
MIR130B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1450,245,041 - 50,245,120 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11450,245,041 - 50,245,120 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21453,695,562 - 53,695,641 (-)NCBISscrofa10.2Sscrofa10.2susScr3

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:8227
Count of gene targets:4978
Count of transcripts:5352
Interacting mature miRNAs:rno-miR-301b-3p, rno-miR-301b-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system reproductive system
High
Medium
Low 5 5 1
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000062155
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1183,879,816 - 83,879,893 (+)Ensembl
Rnor_6.0 Ensembl1188,129,426 - 88,129,503 (+)Ensembl
RefSeq Acc Id: NR_032270
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81197,384,033 - 97,384,110 (+)NCBI
mRatBN7.21183,879,816 - 83,879,893 (+)NCBI
Rnor_6.01188,129,426 - 88,129,503 (+)NCBI
Rnor_5.01191,181,973 - 91,182,050 (+)NCBI
Celera1182,635,547 - 82,635,624 (+)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2325503 AgrOrtholog
BioCyc Gene G2FUF-20571 BioCyc
Ensembl Genes ENSRNOG00000040402 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000062155 ENTREZGENE
miRBase MI0006137 ENTREZGENE
NCBI Gene 100314104 ENTREZGENE
PhenoGen Mir301b PhenoGen
RatGTEx ENSRNOG00000040402 RatGTEx
RNAcentral URS00003952AD RNACentral
  URS0000507675 RNACentral
  URS000075D7E3 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-14 Mir301b  microRNA 301b  Mir301b  microRNA mir-301b  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-06-02 Mir301b  microRNA mir-301b      Symbol and Name status set to provisional 70820 PROVISIONAL