Cks2l1 (CDC28 protein kinase regulatory subunit 2 like 1) - Rat Genome Database

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Gene: Cks2l1 (CDC28 protein kinase regulatory subunit 2 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Cks2l1 (Ensembl: LOC100362620)
Name: CDC28 protein kinase regulatory subunit 2 like 1 (Ensembl:CDC28 protein kinase regulatory subunit 2)
RGD ID: 2324338
Description: Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in cell division.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: AABR07028615.2; CDC28 protein kinase regulatory subunit 2; cyclin-dependent kinases regulatory subunit 2-like; LOC100362620
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81724,477,006 - 24,477,585 (+)NCBIGRCr8
mRatBN7.21724,271,431 - 24,271,897 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1724,271,431 - 24,271,670 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01724,898,905 - 24,899,322 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1777,568,348 - 77,568,506 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01726,835,809 - 26,836,318 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41730,267,398 - 30,267,637 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1723,936,296 - 23,936,709 (+)NCBICelera
Cytogenetic Map17p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Cks2l1
9 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131701463Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17131990913Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17137830672Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
631499Stl1Serum triglyceride level QTL 13.6blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)17327139827389946Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17429913035837242Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17435448727028127Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17435448727028127Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)171864018263640182Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172245492450909196Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172308056759555013Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318457246843Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat

Markers in Region
Cks2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21724,271,441 - 24,271,819 (+)MAPPERmRatBN7.2
Rnor_6.01724,898,916 - 24,899,293NCBIRnor6.0
Rnor_5.01726,835,820 - 26,836,197UniSTSRnor5.0
RGSC_v3.41730,267,409 - 30,267,786UniSTSRGSC3.4
Celera1723,936,307 - 23,936,684UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000076151   ⟹   ENSRNOP00000089255
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1724,271,431 - 24,271,670 (+)Ensembl
RefSeq Acc Id: XM_039096381   ⟹   XP_038952309
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81724,477,006 - 24,477,585 (+)NCBI
mRatBN7.21724,271,431 - 24,271,897 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038952309 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000089255
  ENSRNOP00000089255.1
Reference Protein Sequences
RefSeq Acc Id: XP_038952309   ⟸   XM_039096381
- UniProtKB: A0A8I6ACB4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000089255   ⟸   ENSRNOT00000076151

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-9711 BioCyc
Ensembl Genes ENSRNOG00000051034 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000076151.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.170.10 UniProtKB/TrEMBL
InterPro Cyclin-dep_kinase_reg-sub UniProtKB/TrEMBL
  Cyclin-dep_kinase_reg-sub_sf UniProtKB/TrEMBL
NCBI Gene 100362620 ENTREZGENE
PANTHER CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT 2 UniProtKB/TrEMBL
  CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 UniProtKB/TrEMBL
Pfam CKS UniProtKB/TrEMBL
PhenoGen Cks2l1 PhenoGen
PRINTS CYCLINKINASE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000051034 RatGTEx
SMART CKS UniProtKB/TrEMBL
Superfamily-SCOP SSF55637 UniProtKB/TrEMBL
UniProt A0A8I6ACB4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Cks2l1  CDC28 protein kinase regulatory subunit 2 like 1  LOC100362620  CDC28 protein kinase regulatory subunit 2  Symbol and Name Changed 1299863 APPROVED
2022-06-02 LOC100362620  CDC28 protein kinase regulatory subunit 2  AABR07028615.2    Data merged from RGD:15006110 737654 PROVISIONAL
2019-11-08 AABR07028615.2        Symbol and Name status set to provisional 45752 PROVISIONAL
2010-05-06 LOC100362620  CDC28 protein kinase regulatory subunit 2      Symbol and Name status set to provisional 70820 PROVISIONAL