Tpt1l3 (tumor protein, translationally-controlled 1 like 3) - Rat Genome Database

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Gene: Tpt1l3 (tumor protein, translationally-controlled 1 like 3) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Tpt1l3 (Ensembl: LOC100360791)
Name: tumor protein, translationally-controlled 1 like 3 (Ensembl:tumor protein, translationally-controlled 1)
RGD ID: 2321467
Description: Predicted to enable DNA-binding transcription factor binding activity. Predicted to be involved in negative regulation of ectoderm development and stem cell population maintenance. Predicted to be located in nucleoplasm.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC100360791; Tpt1l1; translationally-controlled tumor protein-like; tumor protein, translationally-controlled 1; tumor protein, translationally-controlled 1 like 1
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8120,926,845 - 20,927,580 (+)NCBIGRCr8
mRatBN7.2119,107,389 - 19,108,208 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl119,107,386 - 19,108,232 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0120,115,903 - 20,116,667 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl120,115,995 - 20,116,513 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0121,603,252 - 21,604,016 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4119,563,430 - 19,563,948 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera117,499,095 - 17,499,859 (+)NCBICelera
Cytogenetic Map1p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
nucleoplasm  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Tpt1l3
9 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:127
Count of miRNA genes:107
Interacting mature miRNAs:117
Transcripts:ENSRNOT00000044222
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70179Xhs2X-ray hypersensitivity QTL 23.2intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)11532110019121980Rat
2298546Neuinf4Neuroinflammation QTL 45.1nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1128736750Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11099206555992065Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1578650Bmd6Bone mineral density QTL 612.2femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)150910843284926Rat
1578651Bmd7Bone mineral density QTL 714.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)150910843284926Rat
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11620621049268520Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)1985600154856001Rat
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1224439043433040Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)11183518156835181Rat
1578669Bss9Bone structure and strength QTL 96.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)150910843284926Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
1354647Despr8Despair related QTL 80.0000341locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1124744506Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1132356093Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1132356093Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)1132356093Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)11148148232355910Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1592587724697545Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)11543162149361612Rat
5684999Bss102Bone structure and strength QTL 1025.50.00000072tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)11543162149361612Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1439328949393289Rat

Markers in Region
MARC_2026-2027:991932441:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2119,107,509 - 19,107,862 (+)MAPPERmRatBN7.2
Rnor_6.0120,116,022 - 20,116,374NCBIRnor6.0
Rnor_5.0121,603,371 - 21,603,723UniSTSRnor5.0
RGSC_v3.4119,563,457 - 19,563,809UniSTSRGSC3.4
Celera117,499,214 - 17,499,566UniSTS
Cytogenetic Map1p12UniSTS
Cytogenetic Map15q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 27 29 29 1 29 55 23 27 1
Low 2 6 9 3 16 3 3 6 11 4 8 6 3
Below cutoff 10 19 9 2 9 5 5 4 8 5 4 5

Sequence


RefSeq Acc Id: ENSRNOT00000044222
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl119,107,386 - 19,108,232 (+)Ensembl
Rnor_6.0 Ensembl120,115,995 - 20,116,513 (+)Ensembl
RefSeq Acc Id: XM_039099022   ⟹   XP_038954950
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8120,926,845 - 20,927,580 (+)NCBI
mRatBN7.2119,107,389 - 19,108,208 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038954950 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000082883.1
  ENSRNOP00000093410
  ENSRNOP00000093410.1
RefSeq Acc Id: XP_038954950   ⟸   XM_039099022
- UniProtKB: A0A8I6GKA0 (UniProtKB/TrEMBL),   A0A8I5ZVT0 (UniProtKB/TrEMBL)
Protein Domains
TCTP

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2321467 AgrOrtholog
BioCyc Gene G2FUF-62149 BioCyc
Ensembl Genes ENSRNOG00000001049 UniProtKB/TrEMBL
  ENSRNOG00000033517 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000044222.5 UniProtKB/TrEMBL
  ENSRNOT00000106386.1 UniProtKB/TrEMBL
InterPro Mss4-like_sf UniProtKB/TrEMBL
  Mss4/transl-control_tumour UniProtKB/TrEMBL
  TCTP UniProtKB/TrEMBL
  Translation_control_tumour_CS UniProtKB/TrEMBL
  Translational_control_tumour_p UniProtKB/TrEMBL
NCBI Gene 100360791 ENTREZGENE
PANTHER PTHR11991 UniProtKB/TrEMBL
  TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN UniProtKB/TrEMBL
Pfam TCTP UniProtKB/TrEMBL
PhenoGen Tpt1l3 PhenoGen
PRINTS TCTPROTEIN UniProtKB/TrEMBL
PROSITE TCTP_1 UniProtKB/TrEMBL
  TCTP_2 UniProtKB/TrEMBL
  TCTP_3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001049 RatGTEx
  ENSRNOG00000033517 RatGTEx
Superfamily-SCOP SSF51316 UniProtKB/TrEMBL
UniProt A0A8I5ZVT0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GKA0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-10-17 Tpt1l3  tumor protein, translationally-controlled 1 like 3  Tpt1l1  tumor protein, translationally-controlled 1 like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2023-09-19 Tpt1l1  tumor protein, translationally-controlled 1 like 1  LOC100360791  tumor protein, translationally-controlled 1  Symbol and Name Changed 1299863 APPROVED
2010-05-06 LOC100360791  tumor protein, translationally-controlled 1      Symbol and Name status set to provisional 70820 PROVISIONAL