Krtap12-2l1 (keratin associated protein 12-2 like 1) - Rat Genome Database

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Gene: Krtap12-2l1 (keratin associated protein 12-2 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Krtap12-2l1 (Ensembl: LOC100361702)
Name: keratin associated protein 12-2 like 1 (Ensembl:keratin associated protein 12-1-like)
RGD ID: 2319572
Description: Orthologous to several human genes including KRTAP12-2 (keratin associated protein 12-2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: keratin associated protein 12-1-like; keratin associated protein 12-2; keratin-associated protein 12-1; Krtap12-2; LOC100361702
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82010,921,265 - 10,921,864 (-)NCBIGRCr8
mRatBN7.22010,921,668 - 10,922,267 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx2011,621,173 - 11,621,772 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02010,982,138 - 10,982,737 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02011,453,888 - 11,454,487 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02011,638,092 - 11,638,689 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2011,638,124 - 11,638,483 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02013,803,475 - 13,803,834 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42011,303,704 - 11,304,063 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2012,426,089 - 12,426,686 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Krtap12-2l1
5 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:37
Count of miRNA genes:34
Interacting mature miRNAs:37
Transcripts:ENSRNOT00000067800
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20362165614101050Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20460660717617956Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20460660717617956Rat
70154Insul2Insulin level QTL 23.75blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20669170617489458Rat
1581577Pur15Proteinuria QTL 154.380.0002urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)20804241017617956Rat
4889870Pur30Proteinuria QTL 30190.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20804241029322208Rat
631265Iresp1Immunoglobin response QTL18.3blood anti-double stranded DNA antibody amount (VT:0004762)serum anti-DNA antibody level (CMO:0001533)20903971913461775Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system hemolymphoid system integumental system musculoskeletal system reproductive system appendage
High
Medium
Low
Below cutoff 2 1 1 1 1 1 1

Sequence


RefSeq Acc Id: ENSRNOT00000067800   ⟹   ENSRNOP00000063582
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2011,638,124 - 11,638,483 (-)Ensembl
RefSeq Acc Id: NM_001402109   ⟹   NP_001389038
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82010,921,265 - 10,921,864 (-)NCBI
mRatBN7.22010,921,668 - 10,922,267 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001389038 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL97089 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: ENSRNOP00000063582   ⟸   ENSRNOT00000067800
RefSeq Acc Id: NP_001389038   ⟸   NM_001402109
- UniProtKB: A6JK73 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M333-F1-model_v2 AlphaFold F1M333 1-109 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701501
Promoter ID:EPDNEW_R12023
Type:single initiation site
Name:LOC100361702_1
Description:keratin associated protein 12-1-like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02011,638,518 - 11,638,578EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2319572 AgrOrtholog
BioCyc Gene G2FUF-4248 BioCyc
Ensembl Genes ENSRNOG00000042956 Ensembl
InterPro KAP UniProtKB/TrEMBL
NCBI Gene 100361702 ENTREZGENE
PANTHER KERATIN ASSOCIATED PROTEIN UniProtKB/TrEMBL
  KERATIN-ASSOCIATED PROTEIN 12-1-RELATED UniProtKB/TrEMBL
Pfam Keratin_B2_2 UniProtKB/TrEMBL
PhenoGen Krtap12-2l1 PhenoGen
RatGTEx ENSRNOG00000042956 RatGTEx
UniProt A6JK73 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-10-13 Krtap12-2l1  keratin associated protein 12-2 like 1  Krtap12-2  keratin associated protein 12-2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2023-09-19 Krtap12-2  keratin associated protein 12-2  LOC100361702  keratin associated protein 12-1-like  Symbol and Name Changed 1299863 APPROVED
2010-05-05 LOC100361702  keratin associated protein 12-1-like      Symbol and Name status set to provisional 70820 PROVISIONAL