LOC100362109 (hypothetical protein LOC100362109) - Rat Genome Database

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Gene: LOC100362109 (hypothetical protein LOC100362109) Rattus norvegicus
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Symbol: LOC100362109
Name: hypothetical protein LOC100362109
RGD ID: 2318773
Description: Orthologous to human C22orf46P (chromosome 22 open reading frame 46, pseudogene); INTERACTS WITH aristolochic acid A (ortholog); benzo[a]pyrene (ortholog); CGP 52608 (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: uncharacterized protein C22orf46 homolog; uncharacterized protein LOC100362109
RGD Orthologs
Human
Mouse
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87115,458,986 - 115,466,378 (+)NCBIGRCr8
mRatBN7.27113,578,871 - 113,586,264 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7113,578,739 - 113,586,266 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.07123,295,519 - 123,304,163 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7123,296,183 - 123,304,066 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07123,280,330 - 123,287,609 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47120,438,220 - 120,445,536 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7109,893,861 - 109,901,652 (+)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
LOC100362109
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87115,458,986 - 115,466,378 (+)NCBIGRCr8
mRatBN7.27113,578,871 - 113,586,264 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7113,578,739 - 113,586,266 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.07123,295,519 - 123,304,163 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7123,296,183 - 123,304,066 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07123,280,330 - 123,287,609 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47120,438,220 - 120,445,536 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7109,893,861 - 109,901,652 (+)NCBICelera
Cytogenetic Map7q34NCBI
C22orf46P
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382241,688,937 - 41,698,136 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2241,688,877 - 41,698,136 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p14 Ensembl2241,690,628 - 41,698,136 (+)EnsemblGRCh38hg38GRCh38
GRCh372242,084,941 - 42,094,140 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362240,416,497 - 40,424,086 (+)NCBINCBI36Build 36hg18NCBI36
Celera2225,892,983 - 25,900,572 (+)NCBICelera
Cytogenetic Map22q13.2NCBI
HuRef2225,051,954 - 25,059,543 (+)NCBIHuRef
CHM1_12242,046,559 - 42,054,152 (+)NCBICHM1_1
T2T-CHM13v2.02242,167,914 - 42,177,110 (+)NCBIT2T-CHM13v2.0
4930407I10Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391581,943,352 - 81,950,739 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1581,943,352 - 81,950,741 (+)EnsemblGRCm39 Ensembl
GRCm381582,059,151 - 82,066,538 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1582,059,151 - 82,066,540 (+)EnsemblGRCm38mm10GRCm38
MGSCv371581,889,581 - 81,896,968 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361581,886,406 - 81,893,793 (+)NCBIMGSCv36mm8
Celera1584,180,805 - 84,188,185 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1538.4NCBI
CUNH22orf46
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541327,176,899 - 27,184,107 (+)NCBIChiLan1.0ChiLan1.0
C10H22orf46
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11023,611,419 - 23,618,178 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1023,544,538 - 23,551,727 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01024,356,416 - 24,363,171 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11024,073,335 - 24,080,089 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01024,392,995 - 24,401,019 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01024,568,602 - 24,575,357 (-)NCBIUU_Cfam_GSD_1.0
LOC101961701
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049457,268,213 - 7,274,708 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936492278,730 - 284,983 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C5H22orf46
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.156,878,161 - 6,884,879 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.254,248,428 - 4,255,702 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103223392
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11924,224,174 - 24,232,019 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666045101,181,078 - 101,185,622 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH22orf46
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247526,965,984 - 6,972,463 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LOC100362109
18 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:82
Count of miRNA genes:70
Interacting mature miRNAs:73
Transcripts:ENSRNOT00000048614
Prediction methods:Microtar, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system hemolymphoid system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 7
Low 1 1 7 1
Below cutoff 1 2 8 2 3 16 18 12 1 2

Sequence


RefSeq Acc Id: ENSRNOT00000048614   ⟹   ENSRNOP00000046655
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7113,578,739 - 113,586,266 (+)Ensembl
Rnor_6.0 Ensembl7123,296,183 - 123,304,066 (+)Ensembl
RefSeq Acc Id: NM_001409219   ⟹   NP_001396148
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87115,458,986 - 115,466,378 (+)NCBI
mRatBN7.27113,578,871 - 113,586,264 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001396148 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000046655
  ENSRNOP00000046655.2
RefSeq Acc Id: ENSRNOP00000046655   ⟸   ENSRNOT00000048614
RefSeq Acc Id: NP_001396148   ⟸   NM_001409219
- UniProtKB: F1LZD2 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LZD2-F1-model_v2 AlphaFold F1LZD2 1-1523 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695529
Promoter ID:EPDNEW_R6051
Type:multiple initiation site
Name:LOC100362109_1
Description:hypothetical protein LOC100362109
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07123,296,146 - 123,296,206EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2318773 AgrOrtholog
BioCyc Gene G2FUF-32645 BioCyc
Ensembl Genes ENSRNOG00000030150 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000048614 ENTREZGENE
  ENSRNOT00000048614.3 UniProtKB/TrEMBL
InterPro DUF4727 UniProtKB/TrEMBL
KEGG Report rno:100362109 UniProtKB/TrEMBL
NCBI Gene 100362109 ENTREZGENE
PANTHER PTHR22379 UniProtKB/TrEMBL
  RIKEN CDNA 4930407I10 GENE UniProtKB/TrEMBL
Pfam DUF4727 UniProtKB/TrEMBL
PhenoGen LOC100362109 PhenoGen
RatGTEx ENSRNOG00000030150 RatGTEx
UniProt F1LZD2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-05-05 LOC100362109  hypothetical protein LOC100362109      Symbol and Name status set to provisional 70820 PROVISIONAL