Tgm7 (transglutaminase 7) - Rat Genome Database

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Gene: Tgm7 (transglutaminase 7) Mus musculus
Analyze
Symbol: Tgm7
Name: transglutaminase 7
RGD ID: 2292252
MGI Page MGI
Description: Predicted to enable protein-glutamine gamma-glutamyltransferase activity. Is expressed in gland and pancreas. Orthologous to human TGM7 (transglutaminase 7).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: protein-glutamine gamma-glutamyltransferase Z; TGMZ; TGz
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392120,923,979 - 120,946,877 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2120,924,046 - 120,946,877 (-)EnsemblGRCm39 Ensembl
GRCm382121,093,498 - 121,116,396 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2121,093,565 - 121,116,396 (-)EnsemblGRCm38mm10GRCm38
MGSCv372120,919,325 - 120,942,132 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362120,777,290 - 120,807,837 (-)NCBIMGSCv36mm8
Celera2122,245,082 - 122,267,686 (-)NCBICelera
Cytogenetic Map2E5NCBI
cM Map260.37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11390390   PMID:14681479   PMID:21267068   PMID:21873635  


Genomics

Comparative Map Data
Tgm7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392120,923,979 - 120,946,877 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2120,924,046 - 120,946,877 (-)EnsemblGRCm39 Ensembl
GRCm382121,093,498 - 121,116,396 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2121,093,565 - 121,116,396 (-)EnsemblGRCm38mm10GRCm38
MGSCv372120,919,325 - 120,942,132 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362120,777,290 - 120,807,837 (-)NCBIMGSCv36mm8
Celera2122,245,082 - 122,267,686 (-)NCBICelera
Cytogenetic Map2E5NCBI
cM Map260.37NCBI
TGM7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381543,276,271 - 43,302,255 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1543,276,271 - 43,302,255 (-)EnsemblGRCh38hg38GRCh38
GRCh371543,568,469 - 43,594,453 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361541,355,771 - 41,381,745 (-)NCBINCBI36Build 36hg18NCBI36
Build 341541,355,770 - 41,381,745NCBI
Celera1520,339,319 - 20,365,298 (-)NCBICelera
Cytogenetic Map15q15.2-q15.3NCBI
HuRef1520,417,271 - 20,443,185 (-)NCBIHuRef
CHM1_11543,687,275 - 43,713,114 (-)NCBICHM1_1
T2T-CHM13v2.01541,083,563 - 41,109,555 (-)NCBIT2T-CHM13v2.0
Tgm7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83128,505,638 - 128,523,298 (-)NCBIGRCr8
mRatBN7.23108,051,890 - 108,068,116 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3108,051,890 - 108,076,239 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.03113,041,577 - 113,130,128 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3113,041,777 - 113,057,791 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03119,581,474 - 119,611,285 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera3106,956,139 - 107,044,508 (-)NCBICelera
Cytogenetic Map3q35NCBI
Tgm7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554169,848,874 - 9,862,166 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554169,847,645 - 9,870,627 (-)NCBIChiLan1.0ChiLan1.0
TGM7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21632,527,747 - 32,553,961 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11536,689,497 - 36,715,695 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01522,237,315 - 22,263,527 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11540,392,135 - 40,418,427 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1540,392,135 - 40,409,516 (-)Ensemblpanpan1.1panPan2
TGM7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13010,134,822 - 10,162,752 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3010,134,810 - 10,157,936 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3010,193,641 - 10,221,596 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03010,270,728 - 10,298,705 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3010,270,556 - 10,293,883 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13010,187,463 - 10,215,420 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03010,308,542 - 10,336,483 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03010,428,399 - 10,456,358 (-)NCBIUU_Cfam_GSD_1.0
Tgm7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864088,599,988 - 88,616,815 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364716,448,157 - 6,460,354 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364716,448,051 - 6,471,521 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TGM7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1128,159,562 - 128,185,274 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11128,153,998 - 128,185,105 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21143,010,656 - 143,041,722 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TGM7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12639,701,467 - 39,717,143 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2639,701,479 - 39,716,964 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048101,296,192 - 101,320,553 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tgm7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480410,398,689 - 10,411,445 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480410,397,837 - 10,419,011 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tgm7
680 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:232
Count of miRNA genes:164
Interacting mature miRNAs:172
Transcripts:ENSMUST00000110675
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274524117129213005Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
1301834Bits1_mbitterness sensitivity 1 (mouse)Not determined287440643121440778Mouse
11532731Sluc31a_msusceptibility to lung cancer 31a (mouse)288015003122015170Mouse
4142223Femwf4_mfemur work to failure 4 (mouse)Not determined88143423122143570Mouse
1301098Cd8mts3_mCD8 memory T cell subset 3 (mouse)Not determined291089974125090104Mouse
1301909Smdq2_msegregation of mitochondrial DNA QTL 2 (mouse)Not determined292778465126778607Mouse
27226761Feml18_mfemur length 18, 16 week (mouse)294230345154241920Mouse
11049569Lmr28d_mleishmaniasis resistance 28d (mouse)297123370131123532Mouse
11049568Lmr28c_mleishmaniasis resistance 28c (mouse)297123370131123532Mouse
12904935Edlmmq2_mextensor digitorum longus muscle mass QTL 2 (mouse)297210364131210364Mouse
12904954Gmmq2_mgastrocnemius muscle mass QTL 2 (mouse)297210364131210364Mouse
4141802Ignpq1_mIgA nephropathy QTL 1 (mouse)Not determined2100824060134824269Mouse
1302203Gvhd3_mgraft-versus host disease 3 (mouse)Not determined2100942930134943090Mouse
1301330Tbbmd2_mtotal body bone mineral density 2 (mouse)Not determined2100942930134943090Mouse
1302071Fembrs1_mfemur breaking strength 1 (mouse)Not determined2100942930134943090Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102630345159941920Mouse
11041906Lmr28a_mleishmaniasis resistance 28a (mouse)2103095716129213005Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse
1301825Pbrgcsf1_mperipheral blood stem cell response to granulocyte colony stimulating factor 1 (mouse)Not determined2106233580140233729Mouse
10043875Bw25_mbody weight QTL 25 (mouse)Not determined2107255676141255676Mouse
1301087Bbaa15_mB.burgdorferi-associated arthritis 15 (mouse)Not determined2110489658144489807Mouse
10045885Cplaq15_mcircadian period of locomotor activity 15 (mouse)Not determined2110916118154354667Mouse
1558990Skmw9_mskeletal muscle weight 9 (mouse)Not determined2111173704145173821Mouse
1300793Pcfm2_mperiosteal circumference and femur length 2 (mouse)Not determined2111173704145173821Mouse
1301905Lgth2_mbody length 2 (mouse)Not determined2111173704145173821Mouse
1301755Hrq1_mheart rate quantitative locus 1 (mouse)Not determined2111173704145173821Mouse
1301201Chab1_mcholesterol absorption 1 (mouse)Not determined2111551028145551163Mouse
1302033Nsv1_mNeuroadapted Sindbis viral RNA level 1 (mouse)Not determined2111623386145623526Mouse
1300798Actre3_mactivity response to ethanol 3 (mouse)Not determined2112024987128173821Mouse
1301415Actre4_mactivity response to ethanol 4 (mouse)Not determined2112024987128173821Mouse
11039520Ltpr2h_mLeishmania tropica response 2h (mouse)2112212746146213005Mouse
11038699Ltpr2b_mLeishmania tropica response 2b (mouse)2112212746146213005Mouse
11038700Ltpr2a_mLeishmania tropica response 2a (mouse)2112212746146213005Mouse
1301029T2dm3_mtype 2 diabetes mellitus 3 (mouse)Not determined2114288075132714157Mouse
11039521Ltpr2g_mLeishmania tropica response 2g (mouse)2115212857149212994Mouse
11038696Ltpr2f_mLeishmania tropica response 2f (mouse)2115212857149212994Mouse
13506762Tbvq2_mtrabecular bone volume QTL 2 (mouse)2115430481124741920Mouse
1558825Aabpr_maberrant activation of B cell proliferation (mouse)Not determined2116033229122207534Mouse
1301295Prdt1_mprion disease incubation time 1 (mouse)Not determined2116077623150077741Mouse
1558881Ses7_msalmonella enteritidis susceptibility 7 (mouse)Not determined2116306330150306474Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2117942930174324863Mouse
12904007Cfq7_mconditioned fear QTL 7 (mouse)2118356772125048872Mouse
12910795Pwbwq5_mpost-weaning body weight QTL 5 (mouse)2118589253160611165Mouse
12910799Pwgrq2_mpre-weaning growth rate QTL 2 (mouse)2118589253160611165Mouse
12910812Pwgrq1_mpre-weaning growth rate QTL 1 (mouse)2118589253160611165Mouse
12910814Pwbwq1_mpre-weaning body weight QTL 1 (mouse)2118589253160611165Mouse

Markers in Region
Tgm7  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382121,093,639 - 121,094,038UniSTSGRCm38
MGSCv372120,919,375 - 120,919,774UniSTSGRCm37
Celera2122,245,132 - 122,245,531UniSTS
Cytogenetic Map2E5UniSTS
cM Map2 UniSTS
UniSTS:234497  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382121,121,230 - 121,121,547UniSTSGRCm38
MGSCv372120,946,966 - 120,947,283UniSTSGRCm37
Celera2122,272,455 - 122,272,772UniSTS
Cytogenetic Map2E5UniSTS
AU014765  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382121,121,284 - 121,121,509UniSTSGRCm38
MGSCv372120,947,020 - 120,947,245UniSTSGRCm37
Celera2122,272,509 - 122,272,734UniSTS
Cytogenetic Map2E5UniSTS
cM Map269.0UniSTS
Whitehead/MRC_RH21523.21UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000110675   ⟹   ENSMUSP00000106303
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2120,924,046 - 120,946,877 (-)Ensembl
GRCm38.p6 Ensembl2121,093,565 - 121,116,396 (-)Ensembl
RefSeq Acc Id: ENSMUST00000238428   ⟹   ENSMUSP00000158669
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2120,924,070 - 120,940,273 (-)Ensembl
GRCm38.p6 Ensembl2121,093,589 - 121,109,792 (-)Ensembl
RefSeq Acc Id: NM_001160424   ⟹   NP_001153896
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392120,924,070 - 120,946,877 (-)NCBI
GRCm382121,093,589 - 121,116,396 (-)NCBI
MGSCv372120,919,325 - 120,942,132 (-)RGD
Celera2122,245,082 - 122,267,686 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006499988   ⟹   XP_006500051
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392120,923,979 - 120,932,337 (-)NCBI
GRCm382121,093,498 - 121,101,856 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011239729   ⟹   XP_011238031
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392120,923,979 - 120,934,180 (-)NCBI
GRCm382121,093,498 - 121,103,699 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001153896 (Get FASTA)   NCBI Sequence Viewer  
  XP_006500051 (Get FASTA)   NCBI Sequence Viewer  
  XP_011238031 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000106303
  ENSMUSP00000106303.3
  ENSMUSP00000158669.2
Reference Protein Sequences
RefSeq Acc Id: NP_001153896   ⟸   NM_001160424
- UniProtKB: A2ART8 (UniProtKB/TrEMBL),   A0A571BDB6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006500051   ⟸   XM_006499988
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011238031   ⟸   XM_011239729
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000106303   ⟸   ENSMUST00000110675
RefSeq Acc Id: ENSMUSP00000158669   ⟸   ENSMUST00000238428
Protein Domains
Transglutaminase-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A2ART8-F1-model_v2 AlphaFold A2ART8 1-710 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2151164 AgrOrtholog
Ensembl Genes ENSMUSG00000079103 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000110675 ENTREZGENE
  ENSMUST00000110675.3 UniProtKB/TrEMBL
  ENSMUST00000238428.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.90.260.10 UniProtKB/TrEMBL
InterPro Gln_gamma-glutamylTfrase_euk UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_E-set UniProtKB/TrEMBL
  Papain_like_cys_pep_sf UniProtKB/TrEMBL
  Transglutaminase-like UniProtKB/TrEMBL
  Transglutaminase-like_sf UniProtKB/TrEMBL
  Transglutaminase_C UniProtKB/TrEMBL
  Transglutaminase_C_sf UniProtKB/TrEMBL
  Transglutaminase_CS UniProtKB/TrEMBL
  Transglutaminase_N UniProtKB/TrEMBL
KEGG Report mmu:640543 UniProtKB/TrEMBL
MGD MGI:2151164 ENTREZGENE
NCBI Gene 640543 ENTREZGENE
PANTHER PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE UniProtKB/TrEMBL
  PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE Z UniProtKB/TrEMBL
Pfam Transglut_C UniProtKB/TrEMBL
  Transglut_core UniProtKB/TrEMBL
  Transglut_N UniProtKB/TrEMBL
PhenoGen Tgm7 PhenoGen
PIRSF TGM_EBP42 UniProtKB/TrEMBL
PROSITE TRANSGLUTAMINASES UniProtKB/TrEMBL
SMART TGc UniProtKB/TrEMBL
Superfamily-SCOP Ig_E-set UniProtKB/TrEMBL
  SSF54001 UniProtKB/TrEMBL
  Transglut_C UniProtKB/TrEMBL
UniProt A0A571BDB6 ENTREZGENE, UniProtKB/TrEMBL
  A2ART8 ENTREZGENE, UniProtKB/TrEMBL