Gene: Aqp2 (aquaporin 2) Rattus norvegicus
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Symbol: Aqp2
Name: aquaporin 2
Description: ENCODES a protein that exhibits actin binding; PDZ domain binding; water transmembrane transporter activity; INVOLVED IN actin filament depolymerization; aging; apoptotic process; PARTICIPATES IN vasopressin signaling pathway; vasopressin signaling pathway via receptor type 2; amiloride pharmacodynamics pathway; ASSOCIATED WITH Diabetes Insipidus, Nephrogenic; Diabetes Mellitus, Experimental; Hypertension; FOUND IN apical plasma membrane; basolateral plasma membrane; clathrin-coated vesicle; INTERACTS WITH (R)-noradrenaline; 17beta-estradiol; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ADH water channel; AQP-2; AQP-CD; aquaporin 2 (collecting duct); aquaporin-2; aquaporin-CD; collecting duct water channel protein; MGC156502; water channel protein for renal collecting duct; WCH-CD
Orthologs:
Homo sapiens (human) : AQP2 (aquaporin 2)  HGNC  AGR
Mus musculus (house mouse) : Aqp2 (aquaporin 2)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Aqp2 (aquaporin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : AQP2 (aquaporin 2)
Canis lupus familiaris (dog) : AQP2 (aquaporin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aqp2 (aquaporin 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07141,237,802 - 141,242,837 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X115,742,312 - 115,747,347 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47138,325,855 - 138,330,891 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17138,402,285 - 138,406,831 (+)NCBI
Celera7127,193,026 - 127,197,996 (+)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Aqp2
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2142
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-11-28
Status: ACTIVE