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Gene-Chemical Interaction Annotations
Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of APOBEC1 mRNA | CTD | PMID:15834898 more ... | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of APOBEC1 mRNA | CTD | PMID:12655037 more ... | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of APOBEC1 mRNA | CTD | PMID:15834898 more ... | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of APOBEC1 mRNA | CTD | PMID:12655037 more ... | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of APOBEC1 mRNA | CTD | PMID:12655037 more ... | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of APOBEC1 mRNA | CTD | PMID:15834898 more ... | 17beta-estradiol | multiple interactions | ISO | RGD:736126 | 6480464 | [Estradiol binds to ESR2 protein] which results in increased expression of APOBEC1 mRNA | CTD | PMID:20404318 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:10174 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of APOBEC1 mRNA | CTD | PMID:16960034 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:10174 | 6480464 | Tetrachlorodibenzodioxin affects the expression of APOBEC1 mRNA | CTD | PMID:21570461 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of APOBEC1 mRNA | CTD | PMID:21346803 | 4,4'-diaminodiphenylmethane | increases expression | ISO | RGD:10174 | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of APOBEC1 mRNA | CTD | PMID:18648102 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of APOBEC1 mRNA | CTD | PMID:16483693 | benzo[a]pyrene | decreases expression | ISO | RGD:10174 | 6480464 | Benzo(a)pyrene results in decreased expression of APOBEC1 mRNA | CTD | PMID:21569818 | benzo[a]pyrene | increases expression | ISO | RGD:10174 | 6480464 | Benzo(a)pyrene results in increased expression of APOBEC1 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | multiple interactions | ISO | RGD:10174 | 6480464 | [Benzo(a)pyrene co-treated with XPA gene mutant form co-treated with TRP53 gene mutant form] results in increased expression of APOBEC1 mRNA | CTD | PMID:21715664 | cadmium dichloride | increases methylation | EXP | | 6480464 | Cadmium Chloride results in increased methylation of APOBEC1 promoter | CTD | PMID:22457795 | clofibric acid | affects expression | EXP | | 6480464 | Clofibric Acid affects the expression of APOBEC1 mRNA | CTD | PMID:17602206 | ethanol | decreases expression | ISO | RGD:10174 | 6480464 | Ethanol results in decreased expression of APOBEC1 mRNA | CTD | PMID:19167417 | kojic acid | decreases expression | ISO | RGD:736126 | 6480464 | kojic acid results in decreased expression of APOBEC1 mRNA | CTD | PMID:16595896 | lead diacetate | decreases expression | EXP | | 6480464 | lead acetate results in decreased expression of APOBEC1 mRNA | CTD | PMID:22641619 | paracetamol | affects expression | ISO | RGD:10174 | 6480464 | Acetaminophen affects the expression of APOBEC1 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of APOBEC1 mRNA | CTD | PMID:17202762 | perfluorooctanoic acid | decreases expression | EXP | | 6480464 | perfluorooctanoic acid results in decreased expression of APOBEC1 mRNA | CTD | PMID:19162173 | phenobarbital | decreases expression | EXP | | 6480464 | Phenobarbital results in decreased expression of APOBEC1 mRNA | CTD | PMID:19162173 | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of APOBEC1 mRNA | CTD | PMID:12832660 | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of APOBEC1 mRNA | CTD | PMID:19162173 | propiconazole | increases expression | ISO | RGD:10174 | 6480464 | propiconazole results in increased expression of APOBEC1 mRNA | CTD | PMID:21278054 | succimer | multiple interactions | ISO | RGD:10174 | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of APOBEC1 mRNA | CTD | PMID:21641980 | valproic acid | affects expression | ISO | RGD:10174 | 6480464 | Valproic Acid affects the expression of APOBEC1 mRNA | CTD | PMID:17963808 | zearalenone | increases expression | EXP | | 6480464 | Zearalenone results in increased expression of APOBEC1 mRNA | CTD | PMID:17557909 | zinc atom | decreases expression | EXP | | 6480464 | Zinc deficiency results in decreased expression of APOBEC1 mRNA | CTD | PMID:10498758 | zinc(0) | decreases expression | EXP | | 6480464 | Zinc deficiency results in decreased expression of APOBEC1 mRNA | CTD | PMID:10498758 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology Annotations
Molecular Pathway Annotations
Disease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals| Apobec1 has been annotated in the following RGD Disease Portals. |
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Comparative Map Data| Apobec1 (Rattus norvegicus) |
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| APOBEC1 (Homo sapiens) |
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| Apobec1 (Mus musculus) |
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Position Markers| UniSTS:224890 |
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QTLs in Region (RGSC Genome Assembly v3.4)| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
Nucleotide Sequences| RefSeq Acc Id: | NM_012907 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Protein Acc Id: | NP_037039 | ||||||||||||||||||||
| Position: |
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Protein Sequences| Protein RefSeqs | NP_037039 | (Get FASTA) |
| GenBank Protein | AAA17394 | (Get FASTA) |
| AAH85335 | (Get FASTA) | |
| EDM01986 | (Get FASTA) | |
| EDM01987 | (Get FASTA) | |
| EDM01988 | (Get FASTA) | |
| P38483 | (Get FASTA) |
Strain Sequence Variants
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External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSRNOG00000015411 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Protein | ENSRNOP00000020735 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Transcript | ENSRNOT00000020735 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Entrez Gene | 25383 | ENTREZGENE |
| Germonline | ENSRNOG00000015411 | UniProtKB/Swiss-Prot |
| HomoloGene Group ID | 1243 | ENTREZGENE |
| IMAGE_CLONE | IMAGE:7301703 | IMAGE-MGC_LOAD |
| InterPro | APOBEC/CMP_deaminase_Zn-bd | UniProtKB/Swiss-Prot |
| APOBEC_N | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:25383 | ENTREZGENE, UniProtKB/Swiss-Prot |
| MGC_CLONE | MGC:105503 | IMAGE-MGC_LOAD |
| Pfam | APOBEC_N | UniProtKB/Swiss-Prot |
| PROSITE | CYT_DCMP_DEAMINASES | UniProtKB/Swiss-Prot |
| TIGR | TC222613 | |
| UniGene | Rn.10002 | ENTREZGENE |
| UniProt | ABEC1_RAT | UniProtKB/Swiss-Prot |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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| 2008-09-25 | Apobec1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 | Apobec1 | apolipoprotein B editing complex 1 | Nomenclature updated to reflect human and mouse nomenclature | 10779 | APPROVED |
| 2002-06-10 | Apobec1 | Apolipoprotein B editing protein | Symbol and Name status set to approved | 1490 | APPROVED |
RGD Curation Notes| Note Type | Note | Reference |
|---|---|---|
| gene_domains | contains several phosphorylation sites | 634661 |
| gene_domains | contains leucine zipper domains | 634661 |
| gene_expression | expressed in small intestine | 634661 |
| gene_process | required for post transcriptional mRNA editing of apolipoprotein B | 634661 |
| gene_process | contributes to post transcriptional cytidine deamination of apolipoprotein B mRNA | 634661 |
| More on Apobec1 | |
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Entrez Gene |
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Ensembl Gene |
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NCBI Map Viewer |
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Vista |
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Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 2133 |
| Created: | 2000-05-25 |
| Species: | Rattus norvegicus |
| Last Modified: | 2013-05-28 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.




