Ap1b1 (adaptor related protein complex 1 subunit beta 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Ap1b1 (adaptor related protein complex 1 subunit beta 1) Rattus norvegicus
Analyze
Symbol: Ap1b1
Name: adaptor related protein complex 1 subunit beta 1
RGD ID: 2064
Description: Enables protein serine/threonine kinase binding activity. Involved in clathrin coat assembly. Predicted to be located in Golgi apparatus and cytosol. Predicted to be part of clathrin coat. Orthologous to human AP1B1 (adaptor related protein complex 1 subunit beta 1); PARTICIPATES IN forkhead class A signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4-tert-Octylphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: adapter-related protein complex 1 subunit beta-1; adaptor protein complex AP-1 subunit beta-1; adaptor protein complex AP-1, beta 1 subunit; adaptor-related protein complex 1 subunit beta-1; adaptor-related protein complex 1, beta 1 subunit; adaptor-related protein complex AP-1 beta 1 subunit; Adtb1; AP-1 complex subunit beta-1; beta-1-adaptin; beta-adaptin 1; beta1-adaptin; clathrin assembly protein complex 1 beta large chain; golgi adaptor HA1/AP1 adaptin beta subunit
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Ap1b1-ps1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81484,093,529 - 84,144,835 (+)NCBIGRCr8
mRatBN7.21479,879,482 - 79,930,778 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1479,879,533 - 79,930,778 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1484,281,794 - 84,333,064 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01485,521,871 - 85,573,146 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01481,971,168 - 82,022,449 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01485,230,652 - 85,281,806 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1485,230,648 - 85,281,803 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01485,927,665 - 85,959,253 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41485,663,840 - 85,695,487 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11485,682,982 - 85,714,630 (+)NCBI
Celera1478,770,483 - 78,821,787 (+)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Plk2 attachment to NSF induces homeostatic removal of GluA2 during chronic overexcitation. Evers DM, etal., Nat Neurosci. 2010 Oct;13(10):1199-207. doi: 10.1038/nn.2624. Epub 2010 Aug 29.
2. The beta 1 and beta 2 subunits of the AP complexes are the clathrin coat assembly components. Gallusser A and Kirchhausen T, EMBO J. 1993 Dec 15;12(13):5237-44.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Structural and functional division into two domains of the large (100- to 115-kDa) chains of the clathrin-associated protein complex AP-2. Kirchhausen T, etal., Proc Natl Acad Sci U S A 1989 Apr;86(8):2612-6.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:7987321   PMID:16025302   PMID:17825088   PMID:18072934   PMID:19199090   PMID:19628795   PMID:21307259   PMID:21700703   PMID:25807483   PMID:26316108   PMID:29476059   PMID:30053369  


Genomics

Comparative Map Data
Ap1b1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81484,093,529 - 84,144,835 (+)NCBIGRCr8
mRatBN7.21479,879,482 - 79,930,778 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1479,879,533 - 79,930,778 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1484,281,794 - 84,333,064 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01485,521,871 - 85,573,146 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01481,971,168 - 82,022,449 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01485,230,652 - 85,281,806 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1485,230,648 - 85,281,803 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01485,927,665 - 85,959,253 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41485,663,840 - 85,695,487 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11485,682,982 - 85,714,630 (+)NCBI
Celera1478,770,483 - 78,821,787 (+)NCBICelera
Cytogenetic Map14q21NCBI
AP1B1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382229,327,680 - 29,388,570 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2229,327,680 - 29,388,583 (-)EnsemblGRCh38hg38GRCh38
GRCh372229,723,669 - 29,784,559 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362228,053,669 - 28,114,569 (-)NCBINCBI36Build 36hg18NCBI36
Build 342228,048,222 - 28,109,123NCBI
Celera2213,523,525 - 13,584,427 (-)NCBICelera
Cytogenetic Map22q12.2ENTREZGENE
HuRef2212,687,908 - 12,748,805 (-)NCBIHuRef
CHM1_12229,683,069 - 29,743,967 (-)NCBICHM1_1
T2T-CHM13v2.02229,791,092 - 29,851,977 (-)NCBIT2T-CHM13v2.0
Ap1b1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39114,897,320 - 4,992,731 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl114,936,824 - 4,992,791 (+)EnsemblGRCm39 Ensembl
GRCm38114,947,320 - 5,042,794 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl114,986,824 - 5,042,791 (+)EnsemblGRCm38mm10GRCm38
MGSCv37114,886,908 - 4,942,732 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36114,886,908 - 4,942,732 (+)NCBIMGSCv36mm8
Celera115,484,717 - 5,540,177 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map113.15NCBI
Ap1b1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554553,632,053 - 3,686,046 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554553,632,053 - 3,686,007 (-)NCBIChiLan1.0ChiLan1.0
AP1B1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22339,311,384 - 39,371,820 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12242,012,016 - 42,072,510 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02210,383,036 - 10,443,655 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12228,189,831 - 28,291,808 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2228,189,831 - 28,285,007 (-)Ensemblpanpan1.1panPan2
AP1B1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12622,632,970 - 22,715,449 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2622,630,670 - 22,689,996 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2622,504,815 - 22,561,619 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02623,007,105 - 23,063,883 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2622,909,397 - 23,101,375 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12622,716,272 - 22,773,450 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02622,979,414 - 23,036,219 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02623,044,435 - 23,101,614 (-)NCBIUU_Cfam_GSD_1.0
Ap1b1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118112,474,816 - 112,527,032 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366573,341,242 - 3,395,957 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366573,343,675 - 3,395,877 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AP1B1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1446,469,430 - 46,520,153 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11446,469,462 - 46,520,175 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21449,434,365 - 49,485,236 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AP1B1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11912,195,981 - 12,259,289 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1912,195,755 - 12,259,272 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045113,891,188 - 113,953,947 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ap1b1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247475,704,477 - 5,755,321 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247475,703,647 - 5,755,344 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ap1b1
214 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:149
Count of miRNA genes:102
Interacting mature miRNAs:122
Transcripts:ENSRNOT00000057407
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143766971982669719Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143766971982669719Rat
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143905723783368335Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)145002321195023211Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1455624247100624247Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)146875779683368335Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1470053989104886043Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1470053989104886043Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147341532392554092Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147341532392554092Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532395876975Rat

Markers in Region
Y07919  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21479,929,960 - 79,930,064 (+)MAPPERmRatBN7.2
Rnor_6.01485,280,989 - 85,281,092NCBIRnor6.0
Rnor_5.01485,958,610 - 85,958,713UniSTSRnor5.0
RGSC_v3.41485,694,844 - 85,694,947UniSTSRGSC3.4
Celera1478,820,970 - 78,821,073UniSTS
Cytogenetic Map14q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 2 4 74 35 41 11 2
Low 6 7 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000057407   ⟹   ENSRNOP00000054218
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1479,879,533 - 79,930,592 (+)Ensembl
Rnor_6.0 Ensembl1485,250,042 - 85,281,630 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000089866   ⟹   ENSRNOP00000072388
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1479,898,950 - 79,930,778 (+)Ensembl
Rnor_6.0 Ensembl1485,230,648 - 85,281,803 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000110241   ⟹   ENSRNOP00000095773
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1479,901,291 - 79,930,778 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000115824   ⟹   ENSRNOP00000096766
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1479,903,668 - 79,928,507 (+)Ensembl
RefSeq Acc Id: NM_001308298   ⟹   NP_001295227
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,093,572 - 84,144,835 (+)NCBI
mRatBN7.21479,879,515 - 79,930,778 (+)NCBI
Rnor_6.01485,230,652 - 85,281,806 (+)NCBI
Celera1478,770,483 - 78,821,787 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039091797   ⟹   XP_038947725
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,093,548 - 84,144,661 (+)NCBI
mRatBN7.21479,879,484 - 79,930,604 (+)NCBI
RefSeq Acc Id: XM_063273008   ⟹   XP_063129078
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,093,548 - 84,144,661 (+)NCBI
RefSeq Acc Id: XM_063273009   ⟹   XP_063129079
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,093,535 - 84,144,661 (+)NCBI
RefSeq Acc Id: XM_063273010   ⟹   XP_063129080
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,093,529 - 84,144,661 (+)NCBI
RefSeq Acc Id: XM_063273011   ⟹   XP_063129081
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,093,549 - 84,144,661 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001295227   ⟸   NM_001308298
- UniProtKB: P52303 (UniProtKB/Swiss-Prot),   A0A0G2K2V2 (UniProtKB/TrEMBL),   A6IKJ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000054218   ⟸   ENSRNOT00000057407
RefSeq Acc Id: ENSRNOP00000072388   ⟸   ENSRNOT00000089866
RefSeq Acc Id: XP_038947725   ⟸   XM_039091797
- Peptide Label: isoform X2
- UniProtKB: P52303 (UniProtKB/Swiss-Prot),   G3V9N8 (UniProtKB/TrEMBL),   A6IKJ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000096766   ⟸   ENSRNOT00000115824
RefSeq Acc Id: ENSRNOP00000095773   ⟸   ENSRNOT00000110241
RefSeq Acc Id: XP_063129080   ⟸   XM_063273010
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063129079   ⟸   XM_063273009
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063129078   ⟸   XM_063273008
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063129081   ⟸   XM_063273011
- Peptide Label: isoform X2
Protein Domains
Beta-adaptin appendage C-terminal subdomain   Clathrin adaptor alpha/beta/gamma-adaptin appendage

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P52303-F1-model_v2 AlphaFold P52303 1-949 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699452
Promoter ID:EPDNEW_R9976
Type:multiple initiation site
Name:Ap1b1_1
Description:adaptor-related protein complex 1, beta 1 subunit
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01485,230,639 - 85,230,699EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2064 AgrOrtholog
BioCyc Gene G2FUF-15156 BioCyc
Ensembl Genes ENSRNOG00000008786 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000057407.5 UniProtKB/TrEMBL
  ENSRNOT00000089866 ENTREZGENE
  ENSRNOT00000089866.2 UniProtKB/TrEMBL
  ENSRNOT00000110241.1 UniProtKB/TrEMBL
  ENSRNOT00000115824.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.1150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.310.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AP_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AP_complex_bsu_1_2_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARM-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Armadillo UniProtKB/TrEMBL
  B-adaptin_app_sub_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Clathrin/coatomer_adapt-like_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Clathrin_a/b/g-adaptin_app_Ig UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Clathrin_app_Ig-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Clathrin_b-adaptin_app_Ig-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Coatomer/calthrin_app_sub_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TBP_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29663 UniProtKB/TrEMBL
NCBI Gene 29663 ENTREZGENE
PANTHER AP-1 COMPLEX SUBUNIT BETA-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11134 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Adaptin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Alpha_adaptinC2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  B2-adapt-app_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ap1b1 PhenoGen
PIRSF AP_complex_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008786 RatGTEx
SMART Alpha_adaptinC2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARM UniProtKB/TrEMBL
  B2-adapt-app_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49348 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55711 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC218103
UniProt A0A0G2K2V2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AM50_RAT UniProtKB/TrEMBL
  A0A8I6AT57_RAT UniProtKB/TrEMBL
  A6IKJ5 ENTREZGENE, UniProtKB/TrEMBL
  A6IKJ6 ENTREZGENE, UniProtKB/TrEMBL
  A6IKJ7_RAT UniProtKB/TrEMBL
  AP1B1_RAT UniProtKB/Swiss-Prot
  G3V9N8 ENTREZGENE, UniProtKB/TrEMBL
  P52303 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-03 Ap1b1  adaptor related protein complex 1 subunit beta 1  Ap1b1  adaptor-related protein complex 1, beta 1 subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Ap1b1  adaptor-related protein complex 1, beta 1 subunit  Ap1b1  adaptor protein complex AP-1, beta 1 subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Ap1b1  adaptor protein complex AP-1, beta 1 subunit      Symbol and Name status set to approved 70586 APPROVED
2001-01-13 Ap1b1  Adaptor protein complex AP-1, beta 1 subunit      Symbol and name updated to reflect Human and Mouse nomenclature 61478 APPROVED
2000-11-11 Adtb1  Adaptor-related protein complex AP-1, beta 1 subunit      Symbol and name withdrawn 61478 WITHDRAWN

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization may be associated with clathrin coated vesicles 70660
gene_expression expressed in brain 70660
gene_function may interact with receptors in clathrin coated vesicles 70660