Gene: Asip (agouti signaling protein) Rattus norvegicus
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Symbol: Asip
Name: agouti signaling protein
Description: ENCODES a protein that exhibits melanocortin receptor binding (ortholog); type 3 melanocortin receptor binding (ortholog); type 4 melanocortin receptor binding (ortholog); INVOLVED IN adult feeding behavior (ortholog); generation of precursor metabolites and energy (ortholog); genetic imprinting (ortholog); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; melanocortin system pathway; ASSOCIATED WITH basal cell carcinoma (ortholog); Carcinoma, Basal Cell (ortholog); Diabetes Mellitus (ortholog); FOUND IN extracellular region (inferred); intracellular (inferred); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; ammonium chloride; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A; agouti; agouti (coat color); agouti switch protein; agouti-signaling protein; ASP
Orthologs:
Homo sapiens (human) : ASIP (agouti signaling protein)  HGNC  AGR
Mus musculus (house mouse) : a (nonagouti)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Asip (agouti signaling protein)
Pan paniscus (bonobo/pygmy chimpanzee) : ASIP (agouti signaling protein)
Canis lupus familiaris (dog) : ASIP (agouti signaling protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Asip (agouti signaling protein)
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Allele / Splice: Asipem1Mcwi   Asipm1  
Genetic Models: DA-Asipm1 ACI.FHH-(D1Mit18-D1Rat90)(D14Mit11-D14Rat33)(D14Rat65-D14Rat90)/EurMcwi-Asipem1Mcwi
Is Marker For: Strains:   BLK/N   F344-AsipATyrCKitH/Kyo  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03150,492,010 - 150,579,870 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03156,860,395 - 156,949,277 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43145,445,175 - 145,536,831 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13145,350,796 - 145,442,453 (+)NCBI
Celera3142,203,571 - 142,291,520 (+)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Asip
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2003
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE