C13h1orf74 (similar to human chromosome 1 open reading frame 74) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: C13h1orf74 (similar to human chromosome 1 open reading frame 74) Rattus norvegicus
Analyze
Symbol: C13h1orf74 (Ensembl: LOC100125367)
Name: similar to human chromosome 1 open reading frame 74 (Ensembl:RIKEN cDNA A130010J15 gene)
RGD ID: 1642423
Description: Orthologous to human C1orf74 (chromosome 1 open reading frame 74); INTERACTS WITH aristolochic acid A (ortholog); benzo[a]pyrene (ortholog); bis(2-chloroethyl) sulfide (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: C1orf74; hypothetical protein LOC100125367; LOC100125367; MGC94716; UPF0739 protein C1orf74 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813107,221,285 - 107,224,063 (+)NCBIGRCr8
mRatBN7.213104,692,769 - 104,695,368 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13104,692,824 - 104,695,470 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13107,210,565 - 107,212,979 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013108,594,417 - 108,596,831 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013105,812,383 - 105,814,797 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013111,890,825 - 111,893,308 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13111,890,894 - 111,893,306 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013116,445,692 - 116,448,212 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413109,007,746 - 109,010,160 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera13104,123,201 - 104,125,615 (+)NCBICelera
Cytogenetic Map13q27NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:15632090  


Genomics

Comparative Map Data
C13h1orf74
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813107,221,285 - 107,224,063 (+)NCBIGRCr8
mRatBN7.213104,692,769 - 104,695,368 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13104,692,824 - 104,695,470 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13107,210,565 - 107,212,979 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013108,594,417 - 108,596,831 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013105,812,383 - 105,814,797 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013111,890,825 - 111,893,308 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13111,890,894 - 111,893,306 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013116,445,692 - 116,448,212 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413109,007,746 - 109,010,160 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera13104,123,201 - 104,125,615 (+)NCBICelera
Cytogenetic Map13q27NCBI
C1orf74
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381209,779,208 - 209,784,559 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1209,779,208 - 209,784,559 (-)EnsemblGRCh38hg38GRCh38
GRCh371209,952,553 - 209,957,904 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361208,022,285 - 208,024,513 (-)NCBINCBI36Build 36hg18NCBI36
Celera1183,186,556 - 183,188,784 (-)NCBICelera
Cytogenetic Map1q32.2NCBI
HuRef1180,630,807 - 180,633,035 (-)NCBIHuRef
CHM1_11211,227,992 - 211,230,220 (-)NCBICHM1_1
T2T-CHM13v2.01209,025,976 - 209,031,327 (-)NCBIT2T-CHM13v2.0
A130010J15Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391192,855,777 - 192,860,145 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1192,850,354 - 192,860,140 (+)EnsemblGRCm39 Ensembl
GRCm381193,173,469 - 193,177,837 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1193,168,046 - 193,177,832 (+)EnsemblGRCm38mm10GRCm38
MGSCv371194,999,663 - 195,004,026 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361194,874,366 - 194,877,027 (+)NCBIMGSCv36mm8
Celera1200,048,553 - 200,052,916 (+)NCBICelera
Cytogenetic Map1H6NCBI
cM Map197.62NCBI
LOC102023042
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554892,439,928 - 2,442,219 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554892,439,927 - 2,462,748 (+)NCBIChiLan1.0ChiLan1.0
C1H1orf74
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2139,612,809 - 39,618,951 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1139,578,971 - 39,585,105 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01185,354,702 - 185,361,089 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11190,158,054 - 190,165,209 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1190,163,274 - 190,164,083 (-)Ensemblpanpan1.1panPan2
C7H1orf74
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.178,440,771 - 8,446,650 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl78,444,907 - 8,446,604 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha78,017,910 - 8,023,788 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.078,141,357 - 8,147,256 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl78,141,016 - 8,147,202 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.178,071,052 - 8,076,940 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.078,168,074 - 8,173,963 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.078,306,167 - 8,312,058 (-)NCBIUU_Cfam_GSD_1.0
CUNH1orf74
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934466,072,527 - 66,100,443 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365573,312,775 - 3,316,440 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365573,312,752 - 3,316,440 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C9H1orf74
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9133,187,742 - 133,193,416 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19133,187,701 - 133,251,760 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29146,263,550 - 146,265,549 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CUNH1orf74
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12519,668,036 - 19,671,527 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2519,670,205 - 19,671,017 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605520,268,364 - 20,278,036 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH1orf74
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248072,212,172 - 2,214,278 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248072,212,178 - 2,325,632 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in C13h1orf74
2 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:614
Count of miRNA genes:273
Interacting mature miRNAs:347
Transcripts:ENSRNOT00000007341
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat

Markers in Region
RH129787  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.213104,691,181 - 104,691,331 (+)MAPPERmRatBN7.2
Rnor_6.013111,889,124 - 111,889,273NCBIRnor6.0
Rnor_5.013116,444,028 - 116,444,177UniSTSRnor5.0
RGSC_v3.413109,005,976 - 109,006,125UniSTSRGSC3.4
Celera13104,121,431 - 104,121,580UniSTS
RH 3.4 Map13759.5UniSTS
Cytogenetic Map13q27UniSTS
RH131251  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.213104,694,963 - 104,695,163 (+)MAPPERmRatBN7.2
Rnor_6.013111,892,906 - 111,893,105NCBIRnor6.0
Rnor_5.013116,447,810 - 116,448,009UniSTSRnor5.0
RGSC_v3.413109,009,758 - 109,009,957UniSTSRGSC3.4
Celera13104,125,213 - 104,125,412UniSTS
RH 3.4 Map13795.6UniSTS
Cytogenetic Map13q27UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 6 6 2 10 7
Low 3 43 51 41 13 41 8 11 72 25 34 11 8
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000007341   ⟹   ENSRNOP00000054032
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl13104,692,824 - 104,695,470 (+)Ensembl
Rnor_6.0 Ensembl13111,890,894 - 111,893,306 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000097977   ⟹   ENSRNOP00000084103
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl13104,692,824 - 104,695,470 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000108080   ⟹   ENSRNOP00000076619
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl13104,693,294 - 104,695,470 (+)Ensembl
RefSeq Acc Id: NM_001103357   ⟹   NP_001096827
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813107,221,649 - 107,224,063 (+)NCBI
mRatBN7.213104,692,952 - 104,695,366 (+)NCBI
Rnor_6.013111,890,894 - 111,893,308 (+)NCBI
Rnor_5.013116,445,692 - 116,448,212 (+)NCBI
RGSC_v3.413109,007,746 - 109,010,160 (+)RGD
Celera13104,123,201 - 104,125,615 (+)RGD
Sequence:
RefSeq Acc Id: XM_017598635   ⟹   XP_017454124
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813107,221,583 - 107,224,063 (+)NCBI
mRatBN7.213104,693,114 - 104,695,368 (+)NCBI
Rnor_6.013111,891,054 - 111,893,308 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039090217   ⟹   XP_038946145
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813107,221,285 - 107,224,063 (+)NCBI
mRatBN7.213104,692,769 - 104,695,368 (+)NCBI
RefSeq Acc Id: NP_001096827   ⟸   NM_001103357
- UniProtKB: Q5U2R2 (UniProtKB/Swiss-Prot),   A6JH22 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454124   ⟸   XM_017598635
- Peptide Label: isoform X1
- UniProtKB: Q5U2R2 (UniProtKB/Swiss-Prot),   A6JH22 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000054032   ⟸   ENSRNOT00000007341
RefSeq Acc Id: XP_038946145   ⟸   XM_039090217
- Peptide Label: isoform X1
- UniProtKB: Q5U2R2 (UniProtKB/Swiss-Prot),   A6JH22 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000076619   ⟸   ENSRNOT00000108080
RefSeq Acc Id: ENSRNOP00000084103   ⟸   ENSRNOT00000097977

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5U2R2-F1-model_v2 AlphaFold Q5U2R2 1-263 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699126
Promoter ID:EPDNEW_R9651
Type:single initiation site
Name:LOC100125367_1
Description:hypothetical protein LOC100125367
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.013111,890,882 - 111,890,942EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1642423 AgrOrtholog
BioCyc Gene G2FUF-16789 BioCyc
Ensembl Genes ENSRNOG00000005558 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055011061 UniProtKB/Swiss-Prot
  ENSRNOG00060013879 UniProtKB/Swiss-Prot
  ENSRNOG00065004156 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000007341 ENTREZGENE
  ENSRNOT00000007341.4 UniProtKB/Swiss-Prot
  ENSRNOT00000097977.1 UniProtKB/Swiss-Prot
  ENSRNOT00000108080.1 UniProtKB/Swiss-Prot
  ENSRNOT00055018736 UniProtKB/Swiss-Prot
  ENSRNOT00055018741 UniProtKB/Swiss-Prot
  ENSRNOT00055018743 UniProtKB/Swiss-Prot
  ENSRNOT00060023716 UniProtKB/Swiss-Prot
  ENSRNOT00060023720 UniProtKB/Swiss-Prot
  ENSRNOT00060023727 UniProtKB/Swiss-Prot
  ENSRNOT00065006050 UniProtKB/Swiss-Prot
  ENSRNOT00065006054 UniProtKB/Swiss-Prot
  ENSRNOT00065006063 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7193261 IMAGE-MGC_LOAD
InterPro DUF4504 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:100125367 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:94716 IMAGE-MGC_LOAD
NCBI Gene 100125367 ENTREZGENE
PANTHER PTHR31366 UniProtKB/Swiss-Prot
  UPF0739 PROTEIN C1ORF74 UniProtKB/Swiss-Prot
  UPF0739 PROTEIN C1ORF74 UniProtKB/TrEMBL
  UPF0739 PROTEIN C1ORF74 UniProtKB/TrEMBL
Pfam DUF4504 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen C13h1orf74 PhenoGen
RatGTEx ENSRNOG00000005558 RatGTEx
  ENSRNOG00055011061 RatGTEx
  ENSRNOG00060013879 RatGTEx
  ENSRNOG00065004156 RatGTEx
UniProt A6JH22 ENTREZGENE, UniProtKB/TrEMBL
  CA074_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 C13h1orf74  similar to human chromosome 1 open reading frame 74  LOC100125367  hypothetical protein LOC100125367  Symbol and Name Changed 1299863 APPROVED
2007-09-15 LOC100125367  hypothetical protein LOC100125367      Symbol and Name status set to provisional 70820 PROVISIONAL