Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | Ppfia2 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of PPFIA2 mRNA] | CTD | PMID:31150632 | aflatoxin B1 | decreases methylation | ISO | PPFIA2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of PPFIA2 gene | CTD | PMID:27153756 | benzo[a]pyrene | increases expression | ISO | PPFIA2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of PPFIA2 mRNA | CTD | PMID:22316170 | benzo[a]pyrene | decreases expression | ISO | PPFIA2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of PPFIA2 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | decreases methylation | ISO | PPFIA2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of PPFIA2 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | PPFIA2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of PPFIA2 exon | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | PPFIA2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of PPFIA2 5' UTR and Benzo(a)pyrene affects the methylation of PPFIA2 promoter | CTD | PMID:27901495 | bisphenol A | multiple interactions | ISO | Ppfia2 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Testosterone] results in increased expression of PPFIA2 mRNA | CTD | PMID:26496021 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PPFIA2 mRNA | CTD | PMID:32156529 | bisphenol A | decreases expression | ISO | Ppfia2 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of PPFIA2 mRNA | CTD | PMID:25181051 and PMID:30816183 | C60 fullerene | decreases expression | ISO | Ppfia2 (Rattus norvegicus) | 6480464 | fullerene C60 results in decreased expression of PPFIA2 mRNA | CTD | PMID:19167457 | cannabidiol | increases expression | ISO | PPFIA2 (Homo sapiens) | 6480464 | Cannabidiol results in increased expression of PPFIA2 mRNA | CTD | PMID:30879928 | endosulfan | decreases expression | ISO | Ppfia2 (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of PPFIA2 mRNA | CTD | PMID:29391264 | entinostat | decreases expression | ISO | PPFIA2 (Homo sapiens) | 6480464 | entinostat results in decreased expression of PPFIA2 mRNA | CTD | PMID:27188386 | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of PPFIA2 mRNA | CTD | PMID:30319688 | fenvalerate | increases expression | ISO | Ppfia2 (Rattus norvegicus) | 6480464 | fenvalerate results in increased expression of PPFIA2 mRNA | CTD | PMID:30307764 | furan | increases expression | ISO | Ppfia2 (Rattus norvegicus) | 6480464 | furan results in increased expression of PPFIA2 mRNA | CTD | PMID:25539665 | genistein | decreases expression | EXP | | 6480464 | Genistein results in decreased expression of PPFIA2 mRNA | CTD | PMID:32186404 | lead(0) | affects expression | ISO | PPFIA2 (Homo sapiens) | 6480464 | Lead affects the expression of PPFIA2 mRNA | CTD | PMID:28903495 | lipopolysaccharide | multiple interactions | ISO | PPFIA2 (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | methoxychlor | affects methylation | ISO | Ppfia2 (Rattus norvegicus) | 6480464 | Methoxychlor affects the methylation of PPFIA2 gene | CTD | PMID:35440735 | N-Nitrosopyrrolidine | decreases expression | ISO | PPFIA2 (Homo sapiens) | 6480464 | N-Nitrosopyrrolidine results in decreased expression of PPFIA2 mRNA | CTD | PMID:32234424 | O-methyleugenol | decreases expression | ISO | PPFIA2 (Homo sapiens) | 6480464 | methyleugenol results in decreased expression of PPFIA2 mRNA | CTD | PMID:32234424 | paracetamol | increases expression | ISO | PPFIA2 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of PPFIA2 mRNA | CTD | PMID:26690555 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of PPFIA2 mRNA | CTD | PMID:20813756 | S-(1,2-dichlorovinyl)-L-cysteine | decreases expression | ISO | PPFIA2 (Homo sapiens) | 6480464 | S-(1 and 2-dichlorovinyl)cysteine results in decreased expression of PPFIA2 mRNA | CTD | PMID:35811015 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | PPFIA2 (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | sodium arsenite | affects methylation | ISO | PPFIA2 (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of PPFIA2 gene | CTD | PMID:28589171 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of PPFIA2 mRNA | CTD | PMID:36209798 and PMID:37682722 | testosterone | multiple interactions | ISO | Ppfia2 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Testosterone] results in increased expression of PPFIA2 mRNA | CTD | PMID:26496021 | tetrachloromethane | decreases expression | ISO | Ppfia2 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of PPFIA2 mRNA | CTD | PMID:31150632 | tetrachloromethane | multiple interactions | ISO | Ppfia2 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of PPFIA2 mRNA] | CTD | PMID:31150632 | urethane | decreases expression | ISO | PPFIA2 (Homo sapiens) | 6480464 | Urethane results in decreased expression of PPFIA2 mRNA | CTD | PMID:28818685 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
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Phenotype Annotations Click to see Annotation Detail View
Mammalian Phenotype
Gene-Chemical Interaction Annotations
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Biological Process
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Phenotype Annotations
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Mammalian Phenotype
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 2. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:8889548 | PMID:10349636 | PMID:11042159 | PMID:11076861 | PMID:11217851 | PMID:12466851 | PMID:12477932 | PMID:15489334 | PMID:16141072 | PMID:16141073 | PMID:16186258 | PMID:16452087 |
| PMID:16959763 | PMID:17114649 | PMID:18054859 | PMID:19013515 | PMID:21267068 | PMID:21618221 | PMID:21873635 | PMID:23791195 | PMID:24194600 | PMID:25838543 | PMID:25921334 | PMID:27889896 |
| PMID:27984743 | PMID:28706196 | PMID:29439199 | PMID:30713523 | PMID:33378226 | PMID:33601422 | PMID:34031393 | PMID:34321999 | PMID:34767769 | PMID:36417873 |
Genomics
Comparative Map Data
| Ppfia2 (Mus musculus - house mouse) |
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| PPFIA2 (Homo sapiens - human) |
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| Ppfia2 (Rattus norvegicus - Norway rat) |
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| Ppfia2 (Chinchilla lanigera - long-tailed chinchilla) |
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| PPFIA2 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| PPFIA2 (Canis lupus familiaris - dog) |
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| Ppfia2 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| PPFIA2 (Sus scrofa - pig) |
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| PPFIA2 (Chlorocebus sabaeus - green monkey) |
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| Ppfia2 (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in Ppfia2
18456 total Variants 
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