Gene: H2-Aa (histocompatibility 2, class II antigen A, alpha)  Mus musculus

Symbol: H2-Aa
Name: histocompatibility 2, class II antigen A, alpha
Description: ENCODES a protein that exhibits peptide antigen binding; protein heterodimerization activity (ortholog); INVOLVED IN antigen processing and presentation; antigen processing and presentation of exogenous peptide antigen via MHC class II; antigen processing and presentation of peptide antigen; PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; asthma disease pathway; ASSOCIATED WITH Amyopathic dermatomyositis (ortholog); Antiphospholipid Syndrome (ortholog); Aortic Aneurysm, Abdominal (ortholog); FOUND IN external side of plasma membrane; lysosome; MHC class II protein complex; INTERACTS WITH menadione; quercetin; 2,2',4,4',5,5'-hexachlorobiphenyl (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: A alpha; Aalpha; H-2 class II histocompatibility antigen, A-B alpha chain; H-2 class II histocompatibility antigen, A-D alpha chain; H-2 class II histocompatibility antigen, A-F alpha chain; H-2 class II histocompatibility antigen, A-K alpha chain; H-2 class II histocompatibility antigen, A-Q alpha chain; H-2 class II histocompatibility antigen, A-R alpha chain; H-2 class II histocompatibility antigen, A-S alpha chain; H-2 class II histocompatibility antigen, A-U alpha chain; H-2 class II histocompatibility antigen, I-E alpha chain; H-2Aa; H2Aa; histocompatibility 2, class II antigen A, alpha; HLA class II histocompatibility antigen, DQ alpha 1 chain; I-Aalpha; Ia-1; Ia1; IAalpha; major histocompatibility protein class II alpha chain; MHC class II antigen; MHC-II I-A(d) alpha; OTTMUSP00000053329; OTTMUSP00000053330
Orthologs: Homo sapiens : HLA-DQA1 (major histocompatibility complex, class II, DQ alpha 1)  HGNC
Rattus norvegicus : RT1-Ba (RT1 class II, locus Ba)
Latest Assembly: Mouse Genome Assembly Build 37
Position:
MapChrPositionStrandSource
Mouse Genome Assembly GRCm381734,282,751 - 34,287,771-NCBI
Mouse cM Map1717.98 NCBI
Mouse Celera Assembly1737,044,263 - 37,049,282-NCBI
Mouse Genome Assembly Build 371734,419,696 - 34,424,716-NCBI
Mouse Genome Assembly Build 36.11734,419,696 - 34,424,716-NCBI
Mouse Cytogenetic Map17 B1 NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on H2-Aa
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RGD Object Information
RGD ID: 1619269
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2013-02-27
Status: ACTIVE