Pebp4 (phosphatidylethanolamine binding protein 4) - Rat Genome Database

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Gene: Pebp4 (phosphatidylethanolamine binding protein 4) Mus musculus
Analyze
Symbol: Pebp4
Name: phosphatidylethanolamine binding protein 4
RGD ID: 1618304
MGI Page MGI
Description: Predicted to be located in extracellular region. Is expressed in bone and rib. Orthologous to human PEBP4 (phosphatidylethanolamine binding protein 4).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1700051A02Rik; 1700081D17Rik; AI429082; PEBP-4; phosphatidylethanolamine-binding protein 4
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391470,077,856 - 70,297,367 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1470,077,869 - 70,297,367 (+)EnsemblGRCm39 Ensembl
GRCm381469,840,407 - 70,059,918 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1469,840,420 - 70,059,918 (+)EnsemblGRCm38mm10GRCm38
MGSCv371470,240,227 - 70,459,693 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361468,575,487 - 68,794,959 (+)NCBIMGSCv36mm8
Celera1467,378,541 - 67,600,399 (+)NCBICelera
Cytogenetic Map14D2NCBI
cM Map1436.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:17143548   PMID:18799693   PMID:21267068  
PMID:21873635   PMID:27033522   PMID:35874667   PMID:36120358   PMID:38472560  


Genomics

Comparative Map Data
Pebp4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391470,077,856 - 70,297,367 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1470,077,869 - 70,297,367 (+)EnsemblGRCm39 Ensembl
GRCm381469,840,407 - 70,059,918 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1469,840,420 - 70,059,918 (+)EnsemblGRCm38mm10GRCm38
MGSCv371470,240,227 - 70,459,693 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361468,575,487 - 68,794,959 (+)NCBIMGSCv36mm8
Celera1467,378,541 - 67,600,399 (+)NCBICelera
Cytogenetic Map14D2NCBI
cM Map1436.1NCBI
PEBP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38822,713,251 - 22,941,077 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl822,713,251 - 23,000,000 (-)EnsemblGRCh38hg38GRCh38
GRCh37822,570,764 - 22,798,590 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36822,626,710 - 22,841,366 (-)NCBINCBI36Build 36hg18NCBI36
Celera821,533,122 - 21,747,804 (-)NCBICelera
Cytogenetic Map8p21.3NCBI
HuRef821,113,907 - 21,329,903 (-)NCBIHuRef
CHM1_1822,773,101 - 22,987,671 (-)NCBICHM1_1
T2T-CHM13v2.0822,987,819 - 23,216,048 (-)NCBIT2T-CHM13v2.0
Pebp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81551,328,127 - 51,543,920 (+)NCBIGRCr8
mRatBN7.21544,920,946 - 45,134,188 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1544,921,886 - 45,134,191 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01551,644,948 - 51,740,626 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.01551,528,587 - 51,615,204 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1551,528,514 - 51,740,281 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01555,252,902 - 55,466,149 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41550,225,405 - 50,460,627 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1544,602,584 - 44,814,601 (+)NCBICelera
Cytogenetic Map15p11NCBI
Pebp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540346,125,150 - 46,333,200 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540346,126,263 - 46,317,830 (-)NCBIChiLan1.0ChiLan1.0
PEBP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2741,218,356 - 41,505,203 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1816,945,744 - 17,232,411 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0821,963,297 - 22,250,024 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1818,902,616 - 19,117,229 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl818,902,734 - 19,117,025 (-)Ensemblpanpan1.1panPan2
PEBP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12534,329,160 - 34,574,086 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2534,317,421 - 34,574,066 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2534,917,144 - 35,164,286 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02534,536,708 - 34,784,007 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2534,535,120 - 34,784,085 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12534,483,438 - 34,730,274 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02534,337,758 - 34,584,606 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02534,492,754 - 34,740,068 (+)NCBIUU_Cfam_GSD_1.0
Pebp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494311,922,656 - 12,137,275 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365556,433,237 - 6,620,072 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365556,433,243 - 6,648,014 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PEBP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl146,966,862 - 7,173,347 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1146,966,861 - 7,173,255 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2147,446,928 - 7,543,617 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.2147,691,260 - 7,698,221 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PEBP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1820,792,718 - 21,066,746 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl820,792,707 - 21,004,134 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605221,223,048 - 21,434,545 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pebp4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475818,203,239 - 18,394,891 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pebp4
5262 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:70
Count of miRNA genes:67
Interacting mature miRNAs:69
Transcripts:ENSMUST00000022678
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420887473121269804Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142106245071885801Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143032195787937436Mouse
10043887Cia50_mcollagen induced arthritis QTL 50 (mouse)Not determined143743018571430320Mouse
4142419Tgq26_mtriglyceride QTL 26 (mouse)Not determined4033731974337319Mouse
1301777Bglq15_mbody growth late QTL 15 (mouse)Not determined144296241676962593Mouse
1301424Skull21_mskull morphology 21 (mouse)Not determined144296241676962593Mouse
1300805Mors3_mmodifier of obesity related sterility 3 (mouse)Not determined144303727077037418Mouse
1301091Bbaa21_mB.burgdorferi-associated arthritis 21 (mouse)Not determined144306584777066045Mouse
4141400Nilac8_mnicotine induced locomotor activity 8 (mouse)Not determined144306584777066045Mouse
1300605El5_mepilepsy 5 (mouse)Not determined144945542583455556Mouse
4142364Pbwg18_mpostnatal body weight growth 18 (mouse)Not determined145228198486282125Mouse
1301489Lbm10_mlean body mass 10 (mouse)Not determined145376129687761529Mouse
12880432Fgf23lq3_mFGF23 serum level QTL 3 (mouse)145393744087937440Mouse
10043889Cia52_mcollagen induced arthritis QTL 52 (mouse)Not determined145608238190082509Mouse
1301562Hwq1_mheart weight quantitative locus 1 (mouse)Not determined145654674590546941Mouse
1357565wrmod1_mwobbler modifier 1 (mouse)Not determined1458179640101859473Mouse
11039527Ccc2_mcolitis susceptibility in the Collaborative Cross 2 (mouse)145991861294138217Mouse
1300666Fembm2_mfemoral bone morphometry 2 (mouse)Not determined146239746096397680Mouse
14747006Mancz12_mmandible centroid size 12 (mouse)1470071977104071977Mouse

Markers in Region
28.MMHAP16FRB10.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381469,979,740 - 69,979,908UniSTSGRCm38
MGSCv371470,379,547 - 70,379,715UniSTSGRCm37
Celera1467,520,020 - 67,520,188UniSTS
Cytogenetic Map14D2UniSTS
Whitehead_YAC14 UniSTS
D14Mit237  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381469,946,226 - 69,946,346UniSTSGRCm38
MGSCv371470,346,033 - 70,346,153UniSTSGRCm37
Celera1467,486,532 - 67,486,652UniSTS
Cytogenetic Map14D2UniSTS
cM Map1432.5UniSTS
Whitehead Genetic1440.4UniSTS
Whitehead_YAC14 UniSTS
D14Mit236  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381470,026,770 - 70,026,886UniSTSGRCm38
MGSCv371470,426,577 - 70,426,693UniSTSGRCm37
Celera1467,567,360 - 67,567,476UniSTS
Cytogenetic Map14D2UniSTS
cM Map1432.5UniSTS
Whitehead Genetic1440.4UniSTS
Whitehead/MRC_RH14793.84UniSTS
Whitehead_YAC14 UniSTS
AI429082  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381470,059,754 - 70,059,845UniSTSGRCm38
MGSCv371470,459,561 - 70,459,652UniSTSGRCm37
Celera1467,600,267 - 67,600,358UniSTS
Cytogenetic Map14D2UniSTS
Whitehead/MRC_RH14791.6UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000022678   ⟹   ENSMUSP00000022678
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1470,077,869 - 70,297,367 (+)Ensembl
GRCm38.p6 Ensembl1469,840,420 - 70,059,918 (+)Ensembl
RefSeq Acc Id: NM_028526   ⟹   NP_082802
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391470,077,856 - 70,089,409 (+)NCBI
GRCm381469,840,407 - 69,851,960 (+)NCBI
MGSCv371470,240,227 - 70,459,693 (+)RGD
Celera1467,378,528 - 67,600,431 (+)NCBI
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_028560   ⟹   NP_082836
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391470,077,856 - 70,297,367 (+)NCBI
GRCm381469,840,407 - 70,059,918 (+)NCBI
MGSCv371470,240,227 - 70,459,693 (+)RGD
Celera1467,378,528 - 67,600,431 (+)NCBI
cM Map14 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_082802   ⟸   NM_028526
- Peptide Label: isoform b precursor
- UniProtKB: Q9D9L9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_082836   ⟸   NM_028560
- Peptide Label: isoform a precursor
- UniProtKB: Q9D9G2 (UniProtKB/Swiss-Prot),   G3X8V3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000022678   ⟸   ENSMUST00000022678

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9D9G2-F1-model_v2 AlphaFold Q9D9G2 1-242 view protein structure

Promoters
RGD ID:8682874
Promoter ID:EPDNEW_M19468
Type:initiation region
Name:Pebp4_1
Description:Mus musculus phosphatidylethanolamine binding protein 4 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19469  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381469,840,436 - 69,840,496EPDNEW
RGD ID:8682876
Promoter ID:EPDNEW_M19469
Type:single initiation site
Name:Pebp4_2
Description:Mus musculus phosphatidylethanolamine binding protein 4 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19468  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381469,847,378 - 69,847,438EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1920773 AgrOrtholog
Ensembl Genes ENSMUSG00000022085 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000022678 ENTREZGENE
  ENSMUST00000022678.5 UniProtKB/Swiss-Prot
Gene3D-CATH 3.90.280.10 UniProtKB/Swiss-Prot
InterPro PEBP UniProtKB/Swiss-Prot
  PEBP-like_sf UniProtKB/Swiss-Prot
  PEBP_euk UniProtKB/Swiss-Prot
  Phosphatidylethanolamine-bd_CS UniProtKB/Swiss-Prot
KEGG Report mmu:73523 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1920773 ENTREZGENE
NCBI Gene 73523 ENTREZGENE
PANTHER PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4 UniProtKB/Swiss-Prot
  PTHR11362 UniProtKB/Swiss-Prot
Pfam PBP UniProtKB/Swiss-Prot
PhenoGen Pebp4 PhenoGen
PROSITE PBP UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49777 UniProtKB/Swiss-Prot
UniProt G3X8V3 ENTREZGENE
  PEBP4_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q9D9L9 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary G3X8V3 UniProtKB/Swiss-Prot