Gene: Eif2ak2 (eukaryotic translation initiation factor 2-alpha kinase 2)  Mus musculus
Symbol: Eif2ak2
Name: eukaryotic translation initiation factor 2-alpha kinase 2
Description: ENCODES a protein that exhibits double-stranded RNA binding; protein kinase activity; INVOLVED IN endoplasmic reticulum unfolded protein response; protein autophosphorylation; protein phosphorylation; PARTICIPATES IN ceramide signaling pathway; platelet-derived growth factor signaling pathway; Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH abnormal cell physiology; decreased erythroid progenitor cell number; decreased sensitivity to induced cell death; ASSOCIATED WITH Amyotrophic Lateral Sclerosis (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH (+)-pilocarpine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310047A08Rik; 4732414G15Rik; AI467567; AI747578; dsRNA-activated kinase; eIF-2 alpha; eIF-2A protein kinase 2; eukaryotic translation initiation factor 2 alpha kinase 2; IFN- type I-induced and dsRNA-activated kinase; IFN-induced and double-stranded RNA-activated kinase; interferon-induced, double-stranded RNA-activated protein kinase; interferon-inducible RNA-dependent protein kinase; OTTMUSP00000051089; P1/eIF-2A protein kinase; p68 kinase; Pkr; Prkr; protein kinase RNA-activated; protein kinase, interferon inducible double stranded RNA dependent; protein kinase, interferon-inducible double stranded RNA dependent; serine/threonine-protein kinase TIK; T-cell viral integration site; Tik; tyrosine-protein kinase EIF2AK2
Orthologs: Homo sapiens : EIF2AK2 (eukaryotic translation initiation factor 2-alpha kinase 2)  HGNC
Rattus norvegicus : Eif2ak2 (eukaryotic translation initiation factor 2-alpha kinase 2)
Latest Assembly: Mouse Genome Assembly Build 37
Position:
MapChrPositionStrandSource
Mouse Genome Assembly GRCm381778,852,550 - 78,882,572-NCBI
Mouse cM Map1749.56 NCBI
Mouse Celera Assembly1783,169,187 - 83,200,883-NCBI
Mouse Genome Assembly Build 371779,251,890 - 79,281,912-NCBI
Mouse Genome Assembly Build 36.11779,251,904 - 79,281,912-NCBI
Mouse Cytogenetic Map17 E2 NCBI
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RGD Object Information
RGD ID: 1616839
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2013-04-09
Status: ACTIVE



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