Trim24 (tripartite motif-containing 24)

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Keyword

Gene: Trim24 (tripartite motif-containing 24) Mus musculus

Symbol:

Trim24

Name:

tripartite motif-containing 24

Description:

The protein encoded by this gene is part of the tripartite-motif containing family (TRIM), which are typified by the RING, B-box type 1, B-box type 2, and coiled-coil region domains. This protein, which also contains a PHD/TTC finger and bromodomain important for regulating nuclear receptors and binding chromatin, has important roles in differentiation, development, and tissue homeostasis. This protein has been reported to regulate the activity of the tumor suppressor p53 and of the retinoic acid receptor. A translocation event between this gene and Braf transforming gene, which results in the fusion protein T18, has been reported in hepatocellular carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jan 2013]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

A130082H20Rik; AI447469; D430004I05Rik; E3 ubiquitin-protein ligase Trim24; OTTMUSP00000039294; OTTMUSP00000039295; OTTMUSP00000039296; TIF1; TIF1-alpha; TIF1-alpha; Tif1a; TIF1alpha; transcription intermediary factor 1-alpha; transcriptional intermediary factor 1, alpha; tripartite motif protein 24; tripartite motif-containing protein 24

Orthologs:

Homo sapiens : TRIM24 (tripartite motif containing 24) HGNC
Rattus norvegicus : Trim24 (tripartite motif-containing 24)

Latest Assembly:

Mouse Genome Assembly Build 37

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly GRCm38	6	37,870,811 - 37,966,292	+	NCBI
Mouse cM Map	6		+	NCBI
Mouse Celera Assembly	6	37,857,341 - 37,952,713	+	NCBI
Mouse Genome Assembly Build 37	6	37,820,811 - 37,916,292	+	NCBI
Mouse Genome Assembly Build 36.1	6	37,820,811 - 37,916,292	+	NCBI
Mouse Cytogenetic Map	6	B1		NCBI