Mir107 (microRNA 107) - Rat Genome Database

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Gene: Mir107 (microRNA 107) Mus musculus
Analyze
Symbol: Mir107
Name: microRNA 107
RGD ID: 1608225
MGI Page MGI
Description: Acts upstream of or within several processes, including cellular response to lipopolysaccharide; miRNA-mediated post-transcriptional gene silencing; and sensory perception of sound. Is expressed in several structures, including branchial arch; central nervous system; embryo mesenchyme; inner ear; and limb bud. Orthologous to human MIR107 (microRNA 107).
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: mir-107; Mirn; Mirn107; mmu-mir-1; mmu-mir-107
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391934,798,087 - 34,798,173 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1934,798,087 - 34,798,173 (-)EnsemblGRCm39 Ensembl
GRCm381934,820,687 - 34,820,773 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1934,820,687 - 34,820,773 (-)EnsemblGRCm38mm10GRCm38
MGSCv371934,895,177 - 34,895,263 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1935,597,534 - 35,597,620 (-)NCBICelera
Cytogenetic Map19C1NCBI
cM Map1929.79NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Depleted tumor suppressor miR-107 in plasma relates to tumor progression and is a novel therapeutic target in pancreatic cancer. Imamura T, etal., Sci Rep. 2017 Jul 18;7(1):5708. doi: 10.1038/s41598-017-06137-8.
2. MicroRNA-107 contributes to post-stroke angiogenesis by targeting Dicer-1. Li Y, etal., Sci Rep. 2015 Aug 21;5:13316. doi: 10.1038/srep13316.
3. Murine hepatic miRNAs expression and regulation of gene expression in diet-induced obese mice. Park JH, etal., Mol Cells. 2011 Jan;31(1):33-8. doi: 10.1007/s10059-011-0009-7. Epub 2010 Nov 25.
4. LncRNA H19 serves as a ceRNA and participates in non-small cell lung cancer development by regulating microRNA-107. Qian B, etal., Eur Rev Med Pharmacol Sci. 2018 Sep;22(18):5946-5953. doi: 10.26355/eurrev_201809_15925.
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Hepatitis C virus-induced changes in microRNA 107 (miRNA-107) and miRNA-449a modulate CCL2 by targeting the interleukin-6 receptor complex in hepatitis. Sarma NJ, etal., J Virol. 2014 Apr;88(7):3733-43. doi: 10.1128/JVI.03060-13. Epub 2014 Jan 15.
7. Biomarkers Associated With Response to Regorafenib in Patients With Hepatocellular Carcinoma. Teufel M, etal., Gastroenterology. 2019 May;156(6):1731-1741. doi: 10.1053/j.gastro.2019.01.261. Epub 2019 Feb 6.
8. MiR-107 suppresses proliferation of hepatoma cells through targeting HMGA2 mRNA 3'UTR. Wang Y, etal., Biochem Biophys Res Commun. 2016 Nov 18;480(3):455-460. doi: 10.1016/j.bbrc.2016.10.070. Epub 2016 Oct 20.
9. miR-107 promotes hepatocellular carcinoma cell proliferation by targeting Axin2. Zhang JJ, etal., Int J Clin Exp Pathol. 2015 May 1;8(5):5168-74. eCollection 2015.
10. Serum microRNA panel for early diagnosis of the onset of hepatocellular carcinoma. Zhang Y, etal., Medicine (Baltimore). 2017 Jan;96(2):e5642. doi: 10.1097/MD.0000000000005642.
Additional References at PubMed
PMID:11914277   PMID:15634332   PMID:16381832   PMID:16766679   PMID:17369397   PMID:17604727   PMID:17671812   PMID:18452032   PMID:18723672   PMID:18762567   PMID:19559694   PMID:20215419  
PMID:20413612   PMID:20489155   PMID:20548288   PMID:20558326   PMID:20603000   PMID:20668074   PMID:20729113   PMID:21037258   PMID:21179570   PMID:21267068   PMID:21415270   PMID:21628465  
PMID:21654750   PMID:21822254   PMID:21841313   PMID:23074224   PMID:23646144   PMID:23940725   PMID:24205035   PMID:24269082   PMID:24293139   PMID:25639731   PMID:26499439   PMID:29286086  
PMID:30311908   PMID:30543171   PMID:30548623   PMID:31852624   PMID:32048816   PMID:33216617   PMID:33529466   PMID:38305705  


Genomics

Comparative Map Data
Mir107
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391934,798,087 - 34,798,173 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1934,798,087 - 34,798,173 (-)EnsemblGRCm39 Ensembl
GRCm381934,820,687 - 34,820,773 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1934,820,687 - 34,820,773 (-)EnsemblGRCm38mm10GRCm38
MGSCv371934,895,177 - 34,895,263 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1935,597,534 - 35,597,620 (-)NCBICelera
Cytogenetic Map19C1NCBI
cM Map1929.79NCBI
MIR107
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381089,592,747 - 89,592,827 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1089,592,747 - 89,592,827 (-)EnsemblGRCh38hg38GRCh38
GRCh371091,352,504 - 91,352,584 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361091,342,483 - 91,342,563 (-)NCBINCBI36Build 36hg18NCBI36
Celera1085,099,321 - 85,099,401 (-)NCBICelera
Cytogenetic Map10q23.31NCBI
HuRef1084,986,456 - 84,986,536 (-)NCBIHuRef
CHM1_11091,634,601 - 91,634,681 (-)NCBICHM1_1
T2T-CHM13v2.01090,476,644 - 90,476,724 (-)NCBIT2T-CHM13v2.0
Mir107
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81241,750,418 - 241,750,504 (-)NCBIGRCr8
mRatBN7.21232,337,767 - 232,337,853 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1232,337,767 - 232,337,853 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1240,733,793 - 240,733,879 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01247,646,828 - 247,646,914 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01240,485,014 - 240,485,100 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01253,128,250 - 253,128,336 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1253,128,250 - 253,128,336 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01260,347,511 - 260,347,597 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1229,451,547 - 229,451,633 (-)NCBICelera
Cytogenetic Map1q53NCBI
MIR107
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1284,484,653 - 4,484,710 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl284,484,646 - 4,484,718 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha284,719,130 - 4,719,187 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0284,706,547 - 4,706,604 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1284,456,978 - 4,457,035 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0284,499,421 - 4,499,478 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0284,635,242 - 4,635,299 (-)NCBIUU_Cfam_GSD_1.0
MIR107
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14101,420,743 - 101,420,829 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114101,420,743 - 101,420,829 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214110,407,095 - 110,407,181 (-)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Mir107
2 total Variants
miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:32301
Count of gene targets:11709
Count of transcripts:20547
Interacting mature miRNAs:mmu-miR-107-3p, mmu-miR-107-5p
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300904Chab5_mcholesterol absorption 5 (mouse)Not determined19165376435653927Mouse
26884385Skwq14_mskull length QTL 14, 16 week (mouse)19325000035877400Mouse
1301800Faq10_mfluctuating asymmetry QTL 10 (mouse)Not determined19332321637323348Mouse
1300923Bits4_mbitterness sensitivity 4 (mouse)Not determined19332321637323348Mouse
1302126Skull26_mskull morphology 26 (mouse)Not determined19332321637323348Mouse
1300591Pas3_mpulmonary adenoma susceptibility 3 (mouse)Not determined19332321637323348Mouse
11039522Tbbr4_mTrypanosoma brucei brucei response 4 (mouse)19531332639313470Mouse
1301228Iba4_minduction of brown adipocytes 4 (mouse)Not determined19930571543305821Mouse
1302019Pgia23_mproteoglycan induced arthritis 23 (mouse)Not determined19978745343787602Mouse
14928311Manh85_mmandible shape 85 (mouse)191191478945914789Mouse
10413881Moe2_mmodifier of epilepsy 2 (mouse)191492301648923138Mouse
1301336Alcp23_malcohol preference locus 23 (mouse)Not determined191591260749912719Mouse
1301633Alcp24_malcohol preference locus 24 (mouse)Not determined191591260749912719Mouse
1302063Eae19_mexperimental allergic encephalomyelitis 19 (mouse)Not determined191829516252295381Mouse
1302004Lfp2_mlong free running period 2 (mouse)Not determined191829516252295381Mouse
4142343Moen2_mmodifier of engrailed QTL 2 (mouse)Not determined192023431454234461Mouse
10412251Mnp_mmodifier of Niemann Pick type C1 (mouse)Not determined192023431454234461Mouse
4141659Pbwg20_mpostnatal body weight growth 20 (mouse)Not determined192137870555378928Mouse
1558876W3q14_mweight 3 weeks QTL 14 (mouse)Not determined192231332653911504Mouse
12790634Ebm1_mEpidermolysis Bullosa modifier 1 (mouse)192498843958988439Mouse
1302123Tlsr8_mthymic lymphoma suppressor region 8 (mouse)Not determined192513600242388916Mouse
1301451Ath16_matherosclerosis 16 (mouse)Not determined192542691759427005Mouse
13506250Renmq1_mrenal mercury accumulation QTL 1 (mouse)192738559461385705Mouse
1357568Tgct4_mtesticular germ cell tumor 4 (mouse)Not determined192777198535295381Mouse
4141138Femwf11_mfemur work to failure 11 (mouse)Not determined2814034861420004Mouse
1300683Fembm7_mfemoral bone morphometry 7 (mouse)Not determined193014122461420004Mouse
1301942Pas13_mpulmonary adenoma susceptibility 13 (mouse)Not determined193014123161420004Mouse
1301410Cd8mts6_mCD8 memory T cell subset 6 (mouse)Not determined193014123161420004Mouse
1300856Nobq2_mNew Zealand obese QTL 2 (mouse)Not determined193089788061420004Mouse
1301741Lith2_mlithogenic gene 2 (mouse)Not determined193299215861420004Mouse
1301639Stnn_mstriatal neuron number (mouse)Not determined193395195261420004Mouse
4141019Tgq29_mtriglyceride QTL 29 (mouse)Not determined3459678661420004Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000083660
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1934,798,087 - 34,798,173 (-)Ensembl
GRCm38.p6 Ensembl1934,820,687 - 34,820,773 (-)Ensembl
RefSeq Acc Id: NR_029783
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391934,798,087 - 34,798,173 (-)NCBI
GRCm381934,820,687 - 34,820,773 (-)ENTREZGENE
MGSCv371934,895,177 - 34,895,263 (-)RGD
Celera1935,597,534 - 35,597,620 (-)RGD
cM Map19 ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3619063 AgrOrtholog
Ensembl Genes ENSMUSG00000065594 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000083660 ENTREZGENE
MGD MGI:3619063 ENTREZGENE
miRBase MI0000684 ENTREZGENE
NCBI Gene 723826 ENTREZGENE
PhenoGen Mir107 PhenoGen
RNAcentral URS0000035FEE RNACentral
  URS00005743AE RNACentral
  URS000075DC2E RNACentral