CCR10 (chemokine (C-C motif) receptor 10)

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Keyword

Gene: CCR10 (chemokine (C-C motif) receptor 10) Homo sapiens

Symbol:

CCR10

Name:

chemokine (C-C motif) receptor 10

Description:

Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008]

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

C-C chemokine receptor type 10; C-C CKR-10; CC chemokine receptor 10; CC-CKR-10; CCR-10; G protein-coupled receptor 2; G-protein coupled receptor 2; GPR2; OTTHUMP00000163143

Orthologs:

Mus musculus : Ccr10 (chemokine (C-C motif) receptor 10) MGI
Rattus norvegicus : Ccr10 (chemokine (C-C motif) receptor 10)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	17	41,620,768 - 41,623,193	-	NCBI
Human Genome Assembly HuRef	17	36,596,485 - 36,598,910	-	NCBI
Human Genome Assembly GRCh37	17	40,831,420 - 40,833,845	-	NCBI
Human Genome Assembly Build 36	17	38,084,946 - 38,087,371	-	NCBI
Human Cytogenetic Map	17	q21.1-q21.3		NCBI