Gene: CKLF (chemokine-like factor)  Homo sapiens

Symbol: CKLF
Name: chemokine-like factor
Description: The product of this gene is a cytokine. Cytokines are small proteins that have an essential role in the immune and inflammatory responses. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. The protein encoded by this gene is a potent chemoattractant for neutrophils, monocytes and lymphocytes. It also can stimulate the proliferation of skeletal muscle cells. This protein may play important roles in inflammation and in the regeneration of skeletal muscle. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CMTM1 (CKLF-like MARVEL transmembrane domain containing 1).[provided by RefSeq, Feb 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C32; chemokine-like factor; chemokine-like factor 1; chemokine-like factor 2; chemokine-like factor 3; chemokine-like factor 4; CKLF1; CKLF2; CKLF3; CKLF4; HSPC224; OTTHUMP00000174791; OTTHUMP00000174792; OTTHUMP00000174793; OTTHUMP00000174794; OTTHUMP00000235182; OTTHUMP00000235183; transmembrane proteolipid; UCK-1
Orthologs: Mus musculus : Cklf (chemokine-like factor)  MGI
Rattus norvegicus : Cklf (chemokine-like factor)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_11667,592,225 - 67,605,948+NCBI
Human Genome Assembly HuRef1652,462,390 - 52,476,113+NCBI
Human Genome Assembly GRCh371666,586,466 - 66,600,190+NCBI
Human Genome Assembly Build 361665,143,967 - 65,157,655+NCBI
Human Cytogenetic Map16q21 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on CKLF
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1606001
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2013-03-06
Status: ACTIVE