Gene: OS9 (osteosarcoma amplified 9, endoplasmic reticulum lectin)  Homo sapiens

Symbol: OS9
Name: osteosarcoma amplified 9, endoplasmic reticulum lectin
Description: This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: amplified in osteosarcoma 9; endoplasmic reticulum lectin 2; ERLEC2; erlectin 2; OS-9; osteosarcoma amplified 9, endoplasmic reticulum associated protein; OTTHUMP00000243422; OTTHUMP00000243423; OTTHUMP00000243428; OTTHUMP00000243429; OTTHUMP00000243431; OTTHUMP00000243432; OTTHUMP00000243433; OTTHUMP00000243435; protein OS-9
Orthologs: Mus musculus : Os9 (amplified in osteosarcoma)  MGI
Rattus norvegicus : Os9 (osteosarcoma amplified 9)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_11257,922,172 - 57,949,773+NCBI
Human Genome Assembly HuRef1255,124,606 - 55,152,176+NCBI
Human Genome Assembly GRCh371258,087,738 - 58,115,340+NCBI
Human Genome Assembly Build 361256,374,153 - 56,401,607+NCBI
Human Cytogenetic Map12q13 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on OS9
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1605693
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2013-03-06
Status: ACTIVE