CEP170 (centrosomal protein 170kDa)

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Keyword

Gene: CEP170 (centrosomal protein 170kDa) Homo sapiens

Symbol:

CEP170

Name:

centrosomal protein 170kDa

Description:

The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

centrosomal protein of 170 kDa; FAM68A; KAB; KARP 1 binding protein; KARP-1-binding protein; KARP1-binding protein; KIAA0470; OTTHUMP00000037806; OTTHUMP00000037807; OTTHUMP00000037808; OTTHUMP00000037809; XRCC5 binding protein

Orthologs:

Mus musculus : Cep170 (centrosomal protein 170) MGI
Rattus norvegicus : Cep170 (centrosomal protein 170)

Related Pseudogenes:

CEP170P1

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	1	250,086,625 - 250,217,713	-	NCBI
Human Genome Assembly HuRef	1	213,646,948 - 213,649,260	-	NCBI
Human Genome Assembly HuRef	1	213,733,812 - 213,798,610	-	NCBI
Human Genome Assembly GRCh37	1	243,287,730 - 243,418,708	-	NCBI
Human Celera Assembly	1	216,649,094 - 216,705,506	-	NCBI
Human Genome Assembly Build 36	1	241,354,353 - 241,485,331	-	NCBI
Human Cytogenetic Map	1	q44		NCBI