Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1H-imidazole | decreases activity | EXP | | 6480464 | imidazole results in decreased activity of SDR16C5 protein | CTD | PMID:18926804 | 2-hydroxypropanoic acid | decreases expression | EXP | | 6480464 | Lactic Acid results in decreased expression of SDR16C5 mRNA | CTD | PMID:30851411 | 2-palmitoylglycerol | increases expression | EXP | | 6480464 | 2-palmitoylglycerol results in increased expression of SDR16C5 mRNA | CTD | PMID:37199045 | 4,4'-sulfonyldiphenol | affects methylation | ISO | Sdr16c5 (Mus musculus) | 6480464 | bisphenol S affects the methylation of SDR16C5 gene | CTD | PMID:31683443 | 4-nonylphenol | multiple interactions | EXP | | 6480464 | [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of SDR16C5 mRNA | CTD | PMID:23626723 | 4-tert-Octylphenol | multiple interactions | EXP | | 6480464 | [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of SDR16C5 mRNA | CTD | PMID:23626723 | aflatoxin B1 | affects expression | EXP | | 6480464 | Aflatoxin B1 affects the expression of SDR16C5 protein | CTD | PMID:20106945 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of SDR16C5 mRNA | CTD | PMID:22100608 | all-trans-retinal | increases reduction | EXP | | 6480464 | SDR16C5 protein results in increased reduction of Retinaldehyde | CTD | PMID:18926804 | all-trans-retinal | increases chemical synthesis | EXP | | 6480464 | SDR16C5 protein results in increased chemical synthesis of Retinaldehyde | CTD | PMID:27793605 | all-trans-retinoic acid | multiple interactions | EXP | | 6480464 | [ALDH1A1 protein co-treated with SDR16C5 protein] results in increased chemical synthesis of Tretinoin | CTD | PMID:27793605 | all-trans-retinoic acid | decreases expression | EXP | | 6480464 | Tretinoin results in decreased expression of SDR16C5 mRNA | CTD | PMID:27793605 | all-trans-retinol | increases oxidation | EXP | | 6480464 | SDR16C5 protein results in increased oxidation of Vitamin A | CTD | PMID:18926804 | all-trans-retinol | increases metabolic processing | EXP | | 6480464 | SDR16C5 protein results in increased metabolism of Vitamin A | CTD | PMID:27793605 | arsane | multiple interactions | EXP | | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of SDR16C5 mRNA | CTD | PMID:32525701 | arsenic atom | multiple interactions | EXP | | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of SDR16C5 mRNA | CTD | PMID:32525701 | arsenite(3-) | multiple interactions | EXP | | 6480464 | [sodium arsenite results in increased abundance of arsenite] which results in decreased expression of SDR16C5 mRNA | CTD | PMID:32076005 | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzo(a)pyrene affects the methylation of SDR16C5 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of SDR16C5 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | decreases methylation | EXP | | 6480464 | Benzo(a)pyrene results in decreased methylation of SDR16C5 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzo(a)pyrene results in increased methylation of SDR16C5 3' UTR | CTD | PMID:27901495 | beta-damascenone | increases expression | ISO | Sdr16c5 (Mus musculus) | 6480464 | beta-damascenone results in increased expression of SDR16C5 mRNA | CTD | PMID:22982537 | bisphenol A | decreases expression | ISO | Sdr16c5 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of SDR16C5 mRNA | CTD | PMID:25181051 | cadmium dichloride | increases methylation | ISO | Sdr16c5 (Rattus norvegicus) | 6480464 | Cadmium Chloride results in increased methylation of SDR16C5 promoter | CTD | PMID:22457795 | calcitriol | increases expression | EXP | | 6480464 | Calcitriol results in increased expression of SDR16C5 mRNA | CTD | PMID:16002434 | copper(II) sulfate | decreases expression | EXP | | 6480464 | Copper Sulfate results in decreased expression of SDR16C5 mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of SDR16C5 mRNA | CTD | PMID:20106945 | dichloroacetic acid | decreases expression | ISO | Sdr16c5 (Mus musculus) | 6480464 | Dichloroacetic Acid results in decreased expression of SDR16C5 mRNA | CTD | PMID:28962523 | endosulfan | decreases expression | ISO | Sdr16c5 (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of SDR16C5 mRNA | CTD | PMID:29391264 | fonofos | increases methylation | EXP | | 6480464 | Fonofos results in increased methylation of SDR16C5 promoter | CTD | PMID:22847954 | lead diacetate | decreases expression | ISO | Sdr16c5 (Mus musculus) | 6480464 | lead acetate results in decreased expression of SDR16C5 mRNA | CTD | PMID:21829687 | N,N-diethyl-m-toluamide | multiple interactions | ISO | Sdr16c5 (Rattus norvegicus) | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of SDR16C5 gene | CTD | PMID:33148267 | N-Nitrosopyrrolidine | increases expression | EXP | | 6480464 | N-Nitrosopyrrolidine results in increased expression of SDR16C5 mRNA | CTD | PMID:32234424 | NAD zwitterion | affects activity | EXP | | 6480464 | NAD affects the activity of SDR16C5 protein | CTD | PMID:18926804 | NAD zwitterion | multiple interactions | EXP | | 6480464 | NAD binds to and results in increased activity of SDR16C5 protein | CTD | PMID:25526675 | NAD(+) | affects activity | EXP | | 6480464 | NAD affects the activity of SDR16C5 protein | CTD | PMID:18926804 | NAD(+) | multiple interactions | EXP | | 6480464 | NAD binds to and results in increased activity of SDR16C5 protein | CTD | PMID:25526675 | O-methyleugenol | increases expression | EXP | | 6480464 | methyleugenol results in increased expression of SDR16C5 mRNA | CTD | PMID:32234424 | p-tert-Amylphenol | multiple interactions | EXP | | 6480464 | [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of SDR16C5 mRNA | CTD | PMID:23626723 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of SDR16C5 mRNA | CTD | PMID:26690555 | parathion | increases methylation | EXP | | 6480464 | Parathion results in increased methylation of SDR16C5 promoter | CTD | PMID:22847954 | permethrin | multiple interactions | ISO | Sdr16c5 (Rattus norvegicus) | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of SDR16C5 gene | CTD | PMID:33148267 | rac-lactic acid | decreases expression | EXP | | 6480464 | Lactic Acid results in decreased expression of SDR16C5 mRNA | CTD | PMID:30851411 | silicon dioxide | increases expression | EXP | | 6480464 | Silicon Dioxide analog results in increased expression of SDR16C5 mRNA | CTD | PMID:25895662 | sodium arsenate | multiple interactions | EXP | | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of SDR16C5 mRNA | CTD | PMID:32525701 | sodium arsenite | multiple interactions | EXP | | 6480464 | [sodium arsenite results in increased abundance of arsenite] which results in decreased expression of SDR16C5 mRNA | CTD | PMID:32076005 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of SDR16C5 mRNA | CTD | PMID:34032870 | sulforaphane | decreases expression | EXP | | 6480464 | sulforaphane results in decreased expression of SDR16C5 mRNA | CTD | PMID:31838189 | terbufos | increases methylation | EXP | | 6480464 | terbufos results in increased methylation of SDR16C5 promoter | CTD | PMID:22847954 | trichloroethene | increases methylation | ISO | Sdr16c5 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased methylation of SDR16C5 gene | CTD | PMID:27618143 | trichostatin A | increases expression | EXP | | 6480464 | trichostatin A results in increased expression of SDR16C5 mRNA | CTD | PMID:24935251 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of SDR16C5 mRNA | CTD | PMID:24935251 | |