NKX2-6 (NK2 homeobox 6) - Rat Genome Database

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Keyword

Gene: NKX2-6 (NK2 homeobox 6) Homo sapiens

Symbol:

NKX2-6

Name:

NK2 homeobox 6

Description:

This gene encodes a homeobox-containing protein that belongs to the NK-2 homeobox family. This protein is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman', which has been shown to be essential for development of the heart-like dorsal vessel. In conjunction with related gene, NKX2-5, this gene may play a role in both pharyngeal and cardiac embryonic development. Mutations in this gene are associated with persistent truncus arteriosus.[provided by RefSeq, Aug 2011]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

CSX2; homeobox protein NK-2 homolog F; homeobox protein NK2 homolog F; homeobox protein Nkx-2.6; homeobox protein NKX2.6; NK2 transcription factor related, locus 6; NKX2F; NKX4-2; OTTHUMP00000225197; tinman paralog

Orthologs:

Mus musculus : Nkx2-6 (NK2 transcription factor related, locus 6 (Drosophila)) MGI
Rattus norvegicus : Nkx2-6 (NK2 homeobox 6)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	8	23,814,215 - 23,818,362	-	NCBI
Human Genome Assembly HuRef	8	22,105,267 - 22,109,415	-	NCBI
Human Genome Assembly GRCh37	8	23,559,964 - 23,564,111	-	NCBI
Human Celera Assembly	8	22,523,400 - 22,527,359	-	NCBI
Human Genome Assembly Build 36	8	23,615,909 - 23,621,070	-	NCBI
Human Cytogenetic Map	8	p21.2		NCBI