Gene: CHST5 (carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5)
Homo sapiens
Symbol:
CHST5
Name:
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
Description:
The protein encoded by this gene belongs to the Gal/GalNAc/GlcNAc 6-O-sulfotransferase (GST) family, members of which catalyze the transfer of sulfate to position 6 of galactose (Gal), N-acetylgalactosamine (GalNAc), or N-acetylglucosamine (GlcNAc) residues within proteoglycans, and sulfation of O-linked sugars of mucin-type acceptors. Carbohydrate sulfation plays a critical role in many biologic processes. This gene is predominantly expressed in colon and small intestine. [provided by RefSeq, Aug 2011]
Type:
protein-coding
RefSeq Status:
REVIEWED
Also known as:
carbohydrate sulfotransferase 5; FLJ22167; galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-alpha; glcNAc6ST-3; glcNAc6ST-3; gn6st-3; gn6st-3; GST4-alpha; hIGn6ST; hIGn6ST; I-GlcNAc-6-ST; I-GlcNAc6ST; I-GlcNAc6ST; intestinal GlcNAc-6-sulfotransferase; intestinal N-acetylglucosamine-6-O-sulfotransferase; MGC74625; N-acetylglucosamine 6-O-sulfotransferase 3; OTTHUMP00000174950
Orthologs:
Mus musculus : Chst5
(carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5)
MGI
Chst5
(carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5)
Latest Assembly:
Human Genome Assembly GRCh37
Position:
Map Chr Position Strand Source Human Alternate Assembly CHM1_1 16 76,574,811 - 76,581,451 - NCBI Human Genome Assembly HuRef 16 61,316,100 - 61,322,740 - NCBI Human Genome Assembly GRCh37 16 75,562,428 - 75,569,068 - NCBI Human Celera Assembly 16 59,856,732 - 59,863,372 - NCBI Human Genome Assembly Build 36 16 74,119,929 - 74,126,569 - NCBI Human Cytogenetic Map 16 q22.3 NCBI
Model
Gene Ontology Annotations
1298488 RA26_H Rheumatoid arthritis QTL 26 (human) .0316 Joint/bone inflammation rheumatoid arthritis 16 71735131 86513319 Human 1358850 MULTSCL10_H Multiple sclerosis susceptibility QTL 10 (human) Multiple sclerosis susceptibility 16 66124225 90185220 Human 1578609 SCL125_H Serum cholesterol level QTL 125 (human) 1.5 Lipid level triglyceride 16 6043155 86386413 Human 1559231 SCL79_H Serum cholesterol level QTL 79 (human) 2.62 Lipid level triglyceride 16 66359506 90185220 Human 1581527 BP70_H Blood pressure QTL 70 (human) 2.2 .001 Blood pressure pulse pressure 16 58735205 84735205 Human 2289240 BW147_H Body weight QTL 147 (human) 2.54 .0003 Body weight BMI 16 53670735 86516334 Human 2289204 BW362_H Body weight QTL 362 (human) .0221 Body fat amount percent fat 16 63683467 89683467 Human 1643062 BW162_H Body weight QTL 162 (human) .0207 Body fat amount percent body fat 16 73386335 90185220 Human 1643055 BW115_H Body Weight QTL 115 (human) 2.59 .00028 Body weight 16 58735205 84735205 Human 2289460 BW216_H Body weight QTL 216 (human) 1.57 Body weight BMI 16 50598916 76598916 Human 2289478 SLEP18_H Serum leptin level QTL 18 (human) 2.98 Hormone level leptin 16 50598916 76598916 Human 2299957 PRSTS332_H Prostate tumor susceptibility QTL 332 (human) 1.07 .0132 Prostate tumor susceptibility 16 71735131 79124295 Human 2293479 PRSTS287_H Prostate tumor susceptibility QTL 287 (human) Prostate tumor susceptibility 16 66045003 90185220 Human 2292949 PRSTS151_H Prostate tumor susceptibility QTL 151 (human) 5.13 .000055 Prostate tumor susceptibility 16 50598916 76598916 Human 2301150 PRSTS400_H Prostate tumor susceptibility QTL 400 (human) 1.59 Prostate tumor susceptibility 16 66124225 90185220 Human 2302770 MAMTS23_H Mammary tumor susceptibility QTL 23 (human) .012 Mammary tumor susceptibility 16 69911496 90185220 Human 2302737 MAMTS24_H Mammary tumor susceptibility QTL 24 (human) .049 Mammary tumor susceptibility 17 69911496 90185220 Human 2315801 GLUCO173_H Glucose level QTL 173 (human) 1.48 .0045 Glucose level 16 73516239 90185220 Human
Gene Ontology Annotations
